ECG-Based Measurements of Drug-induced Repolarization Changes

Tanveer Ahmed Bhuiyan

doi:10.5278/vbn.phd.med.00002

ECG-Based Measurements of Drug-induced Repolarization Changes

Tanveer Ahmed Bhuiyan

Publikation: Ph.d.-afhandling

171 Downloads (Pure)

Abstract

The purpose of this thesis is to investigate the abnormal repolarization both in the cellular and the surface ECG along with their relationship. It has been identified that the certain morphological changes of the monophasic action potential are predictor of TdP arrhythmia. Therefore the proportional changes of the surface ECG which corresponds to the arrhythmia-triggering MAP morphology is warranted to increase the confidence of determining cardiotoxicity of drugs.

Originalsprog	Engelsk
Udgiver	Aalborg Universitetsforlag
ISBN'er, elektronisk	978-87-7112-358-6
DOI	https://doi.org/10.5278/vbn.phd.med.00002
Status	Udgivet - 2015

Bibliografisk note

Johannes Struijk, Hovedvejleder
Claus Graff, Bivejleder

Adgang til dokumentet

10.5278/vbn.phd.med.00002

Tanveer_Ahmed_Bhuiyan_E-pdfForlagets udgivne version, 726 KB

AUB Link

Søg efter materialet i Aalborg Universitetsbiblioteks søgemaskine

Citationsformater

@misc{2385590b64934a4089676ac3820288ed,

title = "ECG-Based Measurements of Drug-induced Repolarization Changes",

abstract = "The purpose of this thesis is to investigate the abnormal repolarization both in the cellular and the surface ECG along with their relationship. It has been identified that the certain morphological changes of the monophasic action potential are predictor of TdP arrhythmia. Therefore the proportional changes of the surface ECG which corresponds to the arrhythmia-triggering MAP morphology is warranted to increase the confidence of determining cardiotoxicity of drugs. ",

author = "Bhuiyan, {Tanveer Ahmed}",

note = "Johannes Struijk, Hovedvejleder Claus Graff, Bivejleder ",

year = "2015",

doi = "10.5278/vbn.phd.med.00002",

language = "English",

series = "Ph.d.-serien for Det Sundhedsvidenskabelige Fakultet, Aalborg Universitet",

publisher = "Aalborg Universitetsforlag",

}

TY - GEN

T1 - ECG-Based Measurements of Drug-induced Repolarization Changes

AU - Bhuiyan, Tanveer Ahmed

N1 - Johannes Struijk, Hovedvejleder Claus Graff, Bivejleder

PY - 2015

Y1 - 2015

N2 - The purpose of this thesis is to investigate the abnormal repolarization both in the cellular and the surface ECG along with their relationship. It has been identified that the certain morphological changes of the monophasic action potential are predictor of TdP arrhythmia. Therefore the proportional changes of the surface ECG which corresponds to the arrhythmia-triggering MAP morphology is warranted to increase the confidence of determining cardiotoxicity of drugs.

AB - The purpose of this thesis is to investigate the abnormal repolarization both in the cellular and the surface ECG along with their relationship. It has been identified that the certain morphological changes of the monophasic action potential are predictor of TdP arrhythmia. Therefore the proportional changes of the surface ECG which corresponds to the arrhythmia-triggering MAP morphology is warranted to increase the confidence of determining cardiotoxicity of drugs.

U2 - 10.5278/vbn.phd.med.00002

DO - 10.5278/vbn.phd.med.00002

M3 - PhD thesis

T3 - Ph.d.-serien for Det Sundhedsvidenskabelige Fakultet, Aalborg Universitet

PB - Aalborg Universitetsforlag

ER -

ECG-Based Measurements of Drug-induced Repolarization Changes

Abstract

Bibliografisk note

Adgang til dokumentet

AUB Link

Fingeraftryk

Citationsformater