TY - JOUR
T1 - Egg consumption, cardiovascular diseases and type 2 diabetes
AU - Geiker, N R W
AU - Larsen, M Lytken
AU - Dyerberg, J
AU - Stender, S
AU - Astrup, A
PY - 2018
Y1 - 2018
N2 - Eggs are rich in nutrients and a source of essential fatty-and amino acids, and the food item with highest cholesterol content. Since the 1970s dietary recommendations have advised limiting egg intake to 2-4 a week for the healthy population, and in those diagnosed with cardiovascular disease (CVD) and type 2 diabetes (T2D) an even more restricted consumption. The aim of the present paper was to assess the recommendation to lower the dietary intake of cholesterol and especially the intake of egg to reduce the risk of CVD and T2D. We performed three web-based literature searches on human studies (observational and interventional) published within the past 10 years during spring 2015. High-quality intervention studies have found nonsignificant effects of increasing the consumption of eggs on risk markers for CVD and T2D in healthy subjects and subjects with T2D. The risk associations found in the observational studies are more likely to be attributed to a dietary pattern often accompanying high egg intake and/or the cluster of other risk factors in people with high egg consumption. Dietary patterns, physical activity and genetics affect the predisposition of CVD and T2D more than a single food item as eggs. In conclusion, up to seven eggs per week can safely be consumed, but in patients with established CVD or T2D only with special emphasis on a healthy lifestyle.
AB - Eggs are rich in nutrients and a source of essential fatty-and amino acids, and the food item with highest cholesterol content. Since the 1970s dietary recommendations have advised limiting egg intake to 2-4 a week for the healthy population, and in those diagnosed with cardiovascular disease (CVD) and type 2 diabetes (T2D) an even more restricted consumption. The aim of the present paper was to assess the recommendation to lower the dietary intake of cholesterol and especially the intake of egg to reduce the risk of CVD and T2D. We performed three web-based literature searches on human studies (observational and interventional) published within the past 10 years during spring 2015. High-quality intervention studies have found nonsignificant effects of increasing the consumption of eggs on risk markers for CVD and T2D in healthy subjects and subjects with T2D. The risk associations found in the observational studies are more likely to be attributed to a dietary pattern often accompanying high egg intake and/or the cluster of other risk factors in people with high egg consumption. Dietary patterns, physical activity and genetics affect the predisposition of CVD and T2D more than a single food item as eggs. In conclusion, up to seven eggs per week can safely be consumed, but in patients with established CVD or T2D only with special emphasis on a healthy lifestyle.
KW - Cardiovascular Diseases/epidemiology
KW - Cholesterol, Dietary/adverse effects
KW - Diabetes Mellitus, Type 2/epidemiology
KW - Diet/adverse effects
KW - Eggs/adverse effects
KW - Evidence-Based Medicine
KW - Healthy Diet
KW - Healthy Lifestyle
KW - Humans
KW - Meta-Analysis as Topic
KW - Risk Factors
KW - Systematic Reviews as Topic
UR - http://www.scopus.com/inward/record.url?scp=85035148799&partnerID=8YFLogxK
U2 - 10.1038/ejcn.2017.153
DO - 10.1038/ejcn.2017.153
M3 - Review article
C2 - 28952608
SN - 0954-3007
VL - 72
SP - 44
EP - 56
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
IS - 1
ER -