Evaluation of Rate of Muscular Force Development in Type 2 Diabetic Individuals with and without Diabetic Peripheral Neuropathy

M. A. Favretto, S. Cossul, F. R. Andreis, J. L. B. Marques

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1 Citationer (Scopus)

Abstrakt

Diabetic peripheral neuropathy (DPN) has been associated with motor dysfunctions, such as reduction in the maximum force of ankle dorsiflexion and muscle atrophy in the lower limbs. These changes contribute to functional limitations, such as changes in gait. The rate of muscular force development (RFD) is derived from the force-time curve obtained during a maximal voluntary isometric contraction (MVIC), performed in a short period of time. RFD seems to be better related to gait changes and neuromuscular dysfunctions than the MVIC. Therefore, the purpose of this study was to evaluate alterations in the RFD in type 2 diabetic individuals with and without DPN. Twenty-two adults participated in the study, divided in three groups: control (n = 8), diabetic without DPN (n = 8) and diabetic with DPN (n = 7). The participants performed three MVIC of the ankle dorsiflexion. To the analysis of the force-time curve, it was selected the highest of the three MVICs obtained. The force-time curve was normalized by the peak value of MVIC. RFD was derived as the slope of the force-time normalized curve over the 0–50% and 0–100% force ranges of the MVIC. The area and time to achieve this ranges were also calculated. The MVIC force was significantly lower (p < 0.05) for the group with DPN (187.78 ± 71.70 N) when compared to the control group (275.77 ± 88.13 N). The RFD(0–50%) was significantly lower (p < 0.05) for the group with DPN (115 ± 44% MVIC/s) in relation to the control group (233 ± 102% MVIC/s). The RFD(0–100%) was significantly lower (p < 0.05) for the groups without DPN (64 ± 22% MVIC/s) and with DPN (61 ± 24% MVIC/s) when compared to the control group (114 ± 45% MVIC/s). We conclude that these alterations may be related to muscle fiber atrophy, and loss of the motor unit caused by diabetes mellitus and DPN.
OriginalsprogEngelsk
TitelXXIV Brazilian Congress on Biomedical Engineering : CBEB 2018, Armação de Buzios, RJ, Brazil, 21-25 October 2018 (Vol. 1)
RedaktørerRodrigo Costa-Felix, André Victor Alvarenga, João Carlos Machado
Antal sider6
Vol/bind1
ForlagSpringer
Publikationsdato2019
Udgave1
Sider31-36
ISBN (Trykt)978-981-13-2118-4
ISBN (Elektronisk)978-981-13-2119-1
DOI
StatusUdgivet - 2019
Udgivet eksterntJa
Begivenhed26th Brazilian Congress on Biomedical Engineering - Armação de Buzios, Brasilien
Varighed: 21 okt. 201825 okt. 2018

Konference

Konference26th Brazilian Congress on Biomedical Engineering
Land/OmrådeBrasilien
ByArmação de Buzios
Periode21/10/201825/10/2018
NavnInternational Federation for Medical and Biological Engineering Proceedings
Vol/bind70
ISSN1680-0737

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