Gait alteration strategies for knee osteoarthritis: A comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques

Christine Mary Dzialo, Marco Mannisi, Kimmo Halonen, Mark de Zee, Jim Woodburn, Michael Skipper Andersen

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Resumé

Gait modifications and laterally wedged insoles are non-invasive approaches used to treat medial compartment knee osteoarthritis. However, the outcome of these alterations is still a controversial topic. This study investigates how gait alteration techniques may have a unique effect on individual patients; and furthermore, the way we scale our musculoskeletal models to estimate the medial joint contact force may influence knee loading conditions. Five patients with clinical evidence of medial knee osteoarthritis were asked to walk at a normal walking speed over force plates and simultaneously 3D motion was captured during seven conditions (0°-, 5°-, 10°-insoles, shod, toe-in, toe-out, and wide stance). We developed patient-specific musculoskeletal models, using segmentations from magnetic resonance imaging to morph a generic model to patient-specific bone geometries and applied this morphing to estimate muscle insertion sites. Additionally, models were created of these patients using a simple linear scaling method. When examining the patients’ medial compartment contact force (peak and impulse) during stance phase, a ‘one-size-fits-all’ gait alteration aimed to reduce medial knee loading did not exist. Moreover, the different scaling methods lead to differences in medial contact forces; highlighting the importance of further investigation of musculoskeletal modeling methods prior to use in the clinical setting.

OriginalsprogEngelsk
Publikationsdato2019
StatusUdgivet - 2019
BegivenhedInternational Society of Biomechanics - Calgary, Canada
Varighed: 31 jul. 20194 aug. 2019
Konferencens nummer: 27
https://isb2019.com/en/

Konference

KonferenceInternational Society of Biomechanics
Nummer27
LandCanada
ByCalgary
Periode31/07/201904/08/2019
Internetadresse

Fingerprint

Knee Osteoarthritis
Gait
Joints
Toes
Knee
Magnetic Resonance Imaging
Bone and Bones
Muscles

Citer dette

Dzialo, C. M., Mannisi, M., Halonen, K., de Zee, M., Woodburn, J., & Andersen, M. S. (2019). Gait alteration strategies for knee osteoarthritis: A comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques. Abstract fra International Society of Biomechanics, Calgary, Canada.
Dzialo, Christine Mary ; Mannisi, Marco ; Halonen, Kimmo ; de Zee, Mark ; Woodburn, Jim ; Andersen, Michael Skipper. / Gait alteration strategies for knee osteoarthritis : A comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques. Abstract fra International Society of Biomechanics, Calgary, Canada.
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abstract = "Gait modifications and laterally wedged insoles are non-invasive approaches used to treat medial compartment knee osteoarthritis. However, the outcome of these alterations is still a controversial topic. This study investigates how gait alteration techniques may have a unique effect on individual patients; and furthermore, the way we scale our musculoskeletal models to estimate the medial joint contact force may influence knee loading conditions. Five patients with clinical evidence of medial knee osteoarthritis were asked to walk at a normal walking speed over force plates and simultaneously 3D motion was captured during seven conditions (0°-, 5°-, 10°-insoles, shod, toe-in, toe-out, and wide stance). We developed patient-specific musculoskeletal models, using segmentations from magnetic resonance imaging to morph a generic model to patient-specific bone geometries and applied this morphing to estimate muscle insertion sites. Additionally, models were created of these patients using a simple linear scaling method. When examining the patients’ medial compartment contact force (peak and impulse) during stance phase, a ‘one-size-fits-all’ gait alteration aimed to reduce medial knee loading did not exist. Moreover, the different scaling methods lead to differences in medial contact forces; highlighting the importance of further investigation of musculoskeletal modeling methods prior to use in the clinical setting.",
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Dzialo, CM, Mannisi, M, Halonen, K, de Zee, M, Woodburn, J & Andersen, MS 2019, 'Gait alteration strategies for knee osteoarthritis: A comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques', International Society of Biomechanics, Calgary, Canada, 31/07/2019 - 04/08/2019.

Gait alteration strategies for knee osteoarthritis : A comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques. / Dzialo, Christine Mary; Mannisi, Marco; Halonen, Kimmo; de Zee, Mark; Woodburn, Jim; Andersen, Michael Skipper.

2019. Abstract fra International Society of Biomechanics, Calgary, Canada.

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

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AU - Halonen, Kimmo

AU - de Zee, Mark

AU - Woodburn, Jim

AU - Andersen, Michael Skipper

PY - 2019

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N2 - Gait modifications and laterally wedged insoles are non-invasive approaches used to treat medial compartment knee osteoarthritis. However, the outcome of these alterations is still a controversial topic. This study investigates how gait alteration techniques may have a unique effect on individual patients; and furthermore, the way we scale our musculoskeletal models to estimate the medial joint contact force may influence knee loading conditions. Five patients with clinical evidence of medial knee osteoarthritis were asked to walk at a normal walking speed over force plates and simultaneously 3D motion was captured during seven conditions (0°-, 5°-, 10°-insoles, shod, toe-in, toe-out, and wide stance). We developed patient-specific musculoskeletal models, using segmentations from magnetic resonance imaging to morph a generic model to patient-specific bone geometries and applied this morphing to estimate muscle insertion sites. Additionally, models were created of these patients using a simple linear scaling method. When examining the patients’ medial compartment contact force (peak and impulse) during stance phase, a ‘one-size-fits-all’ gait alteration aimed to reduce medial knee loading did not exist. Moreover, the different scaling methods lead to differences in medial contact forces; highlighting the importance of further investigation of musculoskeletal modeling methods prior to use in the clinical setting.

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Dzialo CM, Mannisi M, Halonen K, de Zee M, Woodburn J, Andersen MS. Gait alteration strategies for knee osteoarthritis: A comparison of joint loading via generic and patient-specific musculoskeletal model scaling techniques. 2019. Abstract fra International Society of Biomechanics, Calgary, Canada.