Gender differences in asbestos exposure and disease location in 327 patients with mesothelioma

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Resumé

Introduction: The Region of North Denmark has a high incidence of malignant mesothelioma (MM) of 6.2/100.000 for men and 1/100.000 for women mainly due to large-scale use of chrysotile asbestos.Aims: The aim of the study is to investigate gender differences in asbestos exposure and disease location for MM.Methods: Histopathological samples of 236 men and 91 women with MM were retrieved from the Institute of Pathology, Aalborg University Hospital. Asbestos exposure information was harvested from medical records and Danish registries. Asbestos exposure type was categorized as primary, for asbestos workers; domestic, referring to patients living with an asbestos worker; environmental, defined as living or working within 10.000 meters from asbestos emitting location; unknown, where no source of asbestos exposure could be identified. MM location was classified as pleural (MPM) or peritoneal (MAM) disease. Paired T-tests were used to compare the groups (men versus women).Results: Primary asbestos exposure was observed in 88% of men and 9% of women. Significantly more women than men had secondary (domestic, environmental or both) asbestos exposure (P< 0.00001). MAM presented in 18% of the female and 4% of the male patients (P=0.0009) (Figure 1a&b).Conclusions: The main cause of MM in men seems to be primary, in women secondary asbestos exposure. MAM was significantly more frequent in women. Both findings need further study.
OriginalsprogEngelsk
ArtikelnummerPA4294
TidsskriftEuropean Respiratory Journal
Vol/bind50
Udgave nummersuppl 61
ISSN0903-1936
DOI
StatusUdgivet - 2017
BegivenhedERS International Congress 2017 - Milan, Italien
Varighed: 9 sep. 201713 sep. 2017
https://erscongress.org/home2017.html

Konference

KonferenceERS International Congress 2017
LandItalien
ByMilan
Periode09/09/201713/09/2017
Internetadresse

Citer dette

@article{8e16128c98cd4eafaf232a7f8ba5a983,
title = "Gender differences in asbestos exposure and disease location in 327 patients with mesothelioma",
abstract = "Introduction: The Region of North Denmark has a high incidence of malignant mesothelioma (MM) of 6.2/100.000 for men and 1/100.000 for women mainly due to large-scale use of chrysotile asbestos.Aims: The aim of the study is to investigate gender differences in asbestos exposure and disease location for MM.Methods: Histopathological samples of 236 men and 91 women with MM were retrieved from the Institute of Pathology, Aalborg University Hospital. Asbestos exposure information was harvested from medical records and Danish registries. Asbestos exposure type was categorized as primary, for asbestos workers; domestic, referring to patients living with an asbestos worker; environmental, defined as living or working within 10.000 meters from asbestos emitting location; unknown, where no source of asbestos exposure could be identified. MM location was classified as pleural (MPM) or peritoneal (MAM) disease. Paired T-tests were used to compare the groups (men versus women).Results: Primary asbestos exposure was observed in 88{\%} of men and 9{\%} of women. Significantly more women than men had secondary (domestic, environmental or both) asbestos exposure (P< 0.00001). MAM presented in 18{\%} of the female and 4{\%} of the male patients (P=0.0009) (Figure 1a&b).Conclusions: The main cause of MM in men seems to be primary, in women secondary asbestos exposure. MAM was significantly more frequent in women. Both findings need further study.",
author = "Vasiliki Panou and Weinreich, {Ulla Moller} and Jens Bak and Mogens Vyberg and Christos Meristoudis and Oyvind Omland and Roe, {Oluf Dimitri} and Johnni Hansen",
year = "2017",
doi = "10.1183/1393003.congress-2017.PA4294",
language = "English",
volume = "50",
journal = "European Respiratory Journal",
issn = "0903-1936",
publisher = "European Respiratory Society",
number = "suppl 61",

}

Gender differences in asbestos exposure and disease location in 327 patients with mesothelioma. / Panou, Vasiliki; Weinreich, Ulla Moller; Bak, Jens; Vyberg, Mogens; Meristoudis, Christos; Omland, Oyvind; Roe, Oluf Dimitri; Hansen, Johnni.

I: European Respiratory Journal, Bind 50, Nr. suppl 61, PA4294, 2017.

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

TY - ABST

T1 - Gender differences in asbestos exposure and disease location in 327 patients with mesothelioma

AU - Panou, Vasiliki

AU - Weinreich, Ulla Moller

AU - Bak, Jens

AU - Vyberg, Mogens

AU - Meristoudis, Christos

AU - Omland, Oyvind

AU - Roe, Oluf Dimitri

AU - Hansen, Johnni

PY - 2017

Y1 - 2017

N2 - Introduction: The Region of North Denmark has a high incidence of malignant mesothelioma (MM) of 6.2/100.000 for men and 1/100.000 for women mainly due to large-scale use of chrysotile asbestos.Aims: The aim of the study is to investigate gender differences in asbestos exposure and disease location for MM.Methods: Histopathological samples of 236 men and 91 women with MM were retrieved from the Institute of Pathology, Aalborg University Hospital. Asbestos exposure information was harvested from medical records and Danish registries. Asbestos exposure type was categorized as primary, for asbestos workers; domestic, referring to patients living with an asbestos worker; environmental, defined as living or working within 10.000 meters from asbestos emitting location; unknown, where no source of asbestos exposure could be identified. MM location was classified as pleural (MPM) or peritoneal (MAM) disease. Paired T-tests were used to compare the groups (men versus women).Results: Primary asbestos exposure was observed in 88% of men and 9% of women. Significantly more women than men had secondary (domestic, environmental or both) asbestos exposure (P< 0.00001). MAM presented in 18% of the female and 4% of the male patients (P=0.0009) (Figure 1a&b).Conclusions: The main cause of MM in men seems to be primary, in women secondary asbestos exposure. MAM was significantly more frequent in women. Both findings need further study.

AB - Introduction: The Region of North Denmark has a high incidence of malignant mesothelioma (MM) of 6.2/100.000 for men and 1/100.000 for women mainly due to large-scale use of chrysotile asbestos.Aims: The aim of the study is to investigate gender differences in asbestos exposure and disease location for MM.Methods: Histopathological samples of 236 men and 91 women with MM were retrieved from the Institute of Pathology, Aalborg University Hospital. Asbestos exposure information was harvested from medical records and Danish registries. Asbestos exposure type was categorized as primary, for asbestos workers; domestic, referring to patients living with an asbestos worker; environmental, defined as living or working within 10.000 meters from asbestos emitting location; unknown, where no source of asbestos exposure could be identified. MM location was classified as pleural (MPM) or peritoneal (MAM) disease. Paired T-tests were used to compare the groups (men versus women).Results: Primary asbestos exposure was observed in 88% of men and 9% of women. Significantly more women than men had secondary (domestic, environmental or both) asbestos exposure (P< 0.00001). MAM presented in 18% of the female and 4% of the male patients (P=0.0009) (Figure 1a&b).Conclusions: The main cause of MM in men seems to be primary, in women secondary asbestos exposure. MAM was significantly more frequent in women. Both findings need further study.

U2 - 10.1183/1393003.congress-2017.PA4294

DO - 10.1183/1393003.congress-2017.PA4294

M3 - Conference abstract in journal

VL - 50

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - suppl 61

M1 - PA4294

ER -