HLA-DRB1*01:03 and Severe Ulcerative Colitis

Marie Vibeke Vestergaard; Anne Krogh Nøhr; Kristine Allin; Henrik Bygum Krarup; Lone Larsen; Aleksejs Sazonovs; Tine Jess

doi:10.1001/jama.2024.20429

HLA-DRB1*01:03 and Severe Ulcerative Colitis

Marie Vibeke Vestergaard^*, Anne Krogh Nøhr, Kristine Allin, Henrik Bygum Krarup, Lone Larsen, Aleksejs Sazonovs, Tine Jess

^*Kontaktforfatter

Publikation: Bidrag til tidsskrift › Letter › peer review

3 Citationer (Scopus)

Abstract

Ulcerative colitis is a chronic, immune-mediated disease with increasing incidence.1 There is a clinical need to identify biomarkers of severe disease to capture subgroups requiring intensified monitoring and treatment to avoid repeat hospitalizations and surgical procedures.2 This study aimed to identify biomarkers by conducting a Danish nationwide genome-wide association study (GWAS) on severe vs less severe ulcerative colitis.

Originalsprog	Engelsk
Tidsskrift	JAMA
Vol/bind	332
Udgave nummer	22
Sider (fra-til)	1941-1943
Antal sider	3
ISSN	0098-7484
DOI	https://doi.org/10.1001/jama.2024.20429
Status	Udgivet - 10 dec. 2024

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10.1001/jama.2024.20429

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2 Konferenceoplæg

Poster presentation
Vestergaard, M. V. (Foredragsholder)
22 aug. 2025
Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg
Population-wide study identifies HLA-DRB1*01:03 as a strong risk factor for severe ulcerative colitis disease course
Vestergaard, M. V. (Foredragsholder)
15 okt. 2024
Aktivitet: Foredrag og mundtlige bidrag › Konferenceoplæg

Nordjysk forskning: Kan hjælpe udbredt sygdom globalt
Vestergaard, M. V.
17/10/2024 → 20/10/2024
8 elementer af Mediedækning
Presse/medie
Researchers identify gene linked to severe ulcerative colitis
Vestergaard, M. V., Sazonovs, A. & Allin, K.
15/10/2024 → 20/10/2024
19 elementer af Mediedækning
Presse/medie

3 Citationer
1 Ph.d.-afhandling

Enhancing biological insight of inflammatory bowel disease using longitudinal data
Vestergaard, M. V., 2025, Aalborg University Open Publishing.
Publikation: Ph.d.-afhandling

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Citationsformater

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title = "HLA-DRB1*01:03 and Severe Ulcerative Colitis",

abstract = "Ulcerative colitis is a chronic, immune-mediated disease with increasing incidence.1 There is a clinical need to identify biomarkers of severe disease to capture subgroups requiring intensified monitoring and treatment to avoid repeat hospitalizations and surgical procedures.2 This study aimed to identify biomarkers by conducting a Danish nationwide genome-wide association study (GWAS) on severe vs less severe ulcerative colitis.",

author = "Vestergaard, \{Marie Vibeke\} and N{\o}hr, \{Anne Krogh\} and Kristine Allin and Krarup, \{Henrik Bygum\} and Lone Larsen and Aleksejs Sazonovs and Tine Jess",

year = "2024",

month = dec,

day = "10",

doi = "10.1001/jama.2024.20429",

language = "English",

volume = "332",

pages = "1941--1943",

journal = "JAMA",

issn = "0098-7484",

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TY - JOUR

T1 - HLA-DRB1*01:03 and Severe Ulcerative Colitis

AU - Vestergaard, Marie Vibeke

AU - Nøhr, Anne Krogh

AU - Allin, Kristine

AU - Krarup, Henrik Bygum

AU - Larsen, Lone

AU - Sazonovs, Aleksejs

AU - Jess, Tine

PY - 2024/12/10

Y1 - 2024/12/10

N2 - Ulcerative colitis is a chronic, immune-mediated disease with increasing incidence.1 There is a clinical need to identify biomarkers of severe disease to capture subgroups requiring intensified monitoring and treatment to avoid repeat hospitalizations and surgical procedures.2 This study aimed to identify biomarkers by conducting a Danish nationwide genome-wide association study (GWAS) on severe vs less severe ulcerative colitis.

AB - Ulcerative colitis is a chronic, immune-mediated disease with increasing incidence.1 There is a clinical need to identify biomarkers of severe disease to capture subgroups requiring intensified monitoring and treatment to avoid repeat hospitalizations and surgical procedures.2 This study aimed to identify biomarkers by conducting a Danish nationwide genome-wide association study (GWAS) on severe vs less severe ulcerative colitis.

UR - https://www.scopus.com/pages/publications/85209250051

U2 - 10.1001/jama.2024.20429

DO - 10.1001/jama.2024.20429

M3 - Letter

C2 - 39403737

SN - 0098-7484

VL - 332

SP - 1941

EP - 1943

JO - JAMA

JF - JAMA

IS - 22

ER -

HLA-DRB1*01:03 and Severe Ulcerative Colitis

Abstract

Adgang til dokumentet

AUB Link

Andre filer og links

Fingeraftryk

Aktiviteter

Poster presentation

Population-wide study identifies HLA-DRB1*01:03 as a strong risk factor for severe ulcerative colitis disease course

Presse/Medier

Nordjysk forskning: Kan hjælpe udbredt sygdom globalt

Researchers identify gene linked to severe ulcerative colitis

Publikation

Enhancing biological insight of inflammatory bowel disease using longitudinal data

Citationsformater