TY - JOUR
T1 - Identification of Triclosan-O-Sulfate and other transformation products of Triclosan formed by activated sludge
AU - Chen, Xijuan
AU - Casas, Mònica Escolà
AU - Nielsen, Jeppe Lund
AU - Wimmer, Reinhard
AU - Bester, Kai
N1 - Copyright © 2014 Elsevier B.V. All rights reserved.
PY - 2015/2/1
Y1 - 2015/2/1
N2 - Aerobic degradation experiments of Triclosan were performed in activated sludge to identify possible transformation products for this compound. During 7days, the formation of biotransformation products such as 2,4-Dichlorophenol, 4-Chlorocatechol, 5-Hydroxy-Triclosan and other Monohydroxy-Triclosan derivatives as well as Dihydroxy-Triclosan-derivatives were observed. The structure of 5-Hydroxy-Triclosan was elucidated by NMR data for the first time in sludge degradation experiments. Additionally the production of a hitherto unknown transformation product in sludge, i.e., Triclosan-O-Sulfate was detected. During the incubations, the concentrations of this transformation product changed from zero to 330μgL(-1). Based on the analysis of the biodegradation products, three types of reactions were identified: 1) chemical scission of ether bond to form phenols and catechols, 2) addition of OH moieties to the aromatic ring, and 3) adding of methyl or sulfate groups to the original hydroxyl group.
AB - Aerobic degradation experiments of Triclosan were performed in activated sludge to identify possible transformation products for this compound. During 7days, the formation of biotransformation products such as 2,4-Dichlorophenol, 4-Chlorocatechol, 5-Hydroxy-Triclosan and other Monohydroxy-Triclosan derivatives as well as Dihydroxy-Triclosan-derivatives were observed. The structure of 5-Hydroxy-Triclosan was elucidated by NMR data for the first time in sludge degradation experiments. Additionally the production of a hitherto unknown transformation product in sludge, i.e., Triclosan-O-Sulfate was detected. During the incubations, the concentrations of this transformation product changed from zero to 330μgL(-1). Based on the analysis of the biodegradation products, three types of reactions were identified: 1) chemical scission of ether bond to form phenols and catechols, 2) addition of OH moieties to the aromatic ring, and 3) adding of methyl or sulfate groups to the original hydroxyl group.
U2 - 10.1016/j.scitotenv.2014.09.077
DO - 10.1016/j.scitotenv.2014.09.077
M3 - Journal article
C2 - 25306094
SN - 0048-9697
VL - 505C
SP - 39
EP - 46
JO - Science of the Total Environment
JF - Science of the Total Environment
ER -