In vivo charge injection limits increased after 'unsafe' stimulation

Suzan Meijs; Søren Sørensen; Kristian Rechendorff; Nico Rijkhoff

doi:10.5220/0005606301010105

In vivo charge injection limits increased after 'unsafe' stimulation

Suzan Meijs, Søren Sørensen, Kristian Rechendorff, Nico Rijkhoff

Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceartikel i proceeding › Forskning › peer review

Abstract

The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the ‘safe potential window’ may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.

Originalsprog	Engelsk
Titel	Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal
Forlag	SCITEPRESS Digital Library
Publikationsdato	2015
Sider	101-105
ISBN (Trykt)	978-989-758-161-8
DOI	https://doi.org/10.5220/0005606301010105
Status	Udgivet - 2015
Begivenhed	International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX - Lisbon, Portugal Varighed: 16 nov. 2015 → 17 nov. 2015 Konferencens nummer: 3

Konference

Konference	International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX
Nummer	3
Land/Område	Portugal
By	Lisbon
Periode	16/11/2015 → 17/11/2015

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10.5220/0005606301010105

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Citationsformater

Meijs, S., Sørensen, S., Rechendorff, K., & Rijkhoff, N. (2015). In vivo charge injection limits increased after 'unsafe' stimulation. I Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal (s. 101-105). SCITEPRESS Digital Library. https://doi.org/10.5220/0005606301010105

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title = "In vivo charge injection limits increased after 'unsafe' stimulation",

abstract = "The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the {\textquoteleft}safe potential window{\textquoteright} may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.",

author = "Suzan Meijs and S{\o}ren S{\o}rensen and Kristian Rechendorff and Nico Rijkhoff",

year = "2015",

doi = "10.5220/0005606301010105",

language = "English",

isbn = "978-989-758-161-8",

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booktitle = "Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal",

publisher = "SCITEPRESS Digital Library",

note = "International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX ; Conference date: 16-11-2015 Through 17-11-2015",

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Meijs, S, Sørensen, S, Rechendorff, K & Rijkhoff, N 2015, In vivo charge injection limits increased after 'unsafe' stimulation. i Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal. SCITEPRESS Digital Library, s. 101-105, International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX, Lisbon, Portugal, 16/11/2015. https://doi.org/10.5220/0005606301010105

In vivo charge injection limits increased after 'unsafe' stimulation. / Meijs, Suzan; Sørensen, Søren; Rechendorff, Kristian et al.
Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal. SCITEPRESS Digital Library, 2015. s. 101-105.

Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceartikel i proceeding › Forskning › peer review

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T1 - In vivo charge injection limits increased after 'unsafe' stimulation

AU - Meijs, Suzan

AU - Sørensen, Søren

AU - Rechendorff, Kristian

AU - Rijkhoff, Nico

N1 - Conference code: 3

PY - 2015

Y1 - 2015

N2 - The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the ‘safe potential window’ may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.

AB - The effect of unsafe stimulation on charge injection limits (Qinj) and pulsing capacitance (Cpulse) was investigated. Four stimulation protocols were applied: 20 mA – 200 and 400 Hz, 50 mA – 200 and 400 Hz. Increasing Qinj and Cpulse were observed for all stimulation protocols. Corrosion was not observed with any of the stimulation protocols and no tissue damage was observed for the 20 mA – 200 Hz stimulation group. This indicates that the ‘safe potential window’ may not be applicable in vivo, as no damage was done stimulating with 20 mA at 200 Hz, while damage was done using the same current at 400 Hz.

U2 - 10.5220/0005606301010105

DO - 10.5220/0005606301010105

M3 - Article in proceeding

SN - 978-989-758-161-8

SP - 101

EP - 105

BT - Proceedings of the 3rd International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX 2015, 16-17 November 2015, Lisbon, Portugal

PB - SCITEPRESS Digital Library

T2 - International Congress on Neurotechnology, Electronics and Informatics, NEUROTECHNIX

Y2 - 16 November 2015 through 17 November 2015

ER -

In vivo charge injection limits increased after 'unsafe' stimulation

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