TY - JOUR
T1 - Impaired postural control in diabetes – a predictor of falls?
AU - Rasmussen, Nicklas Højgaard-Hessellund
AU - Dal, Jakob
AU - Jensen, Morten Hasselstrøm
AU - Kvist, Annika Vestergaard
AU - van den Bergh, Joop
AU - Hirata, Rogerio Pessoto
AU - Vestergaard, Peter
N1 - © 2022. International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.
PY - 2022/12/9
Y1 - 2022/12/9
N2 - Summary: New evidence points toward that impaired postural control judged by center of pressure measures during quiet stance is a predictor of falls in people with type 1 and type 2 diabetes—even in occurrence of well-known risk factors for falls. Introduction/aim: People with type 1 diabetes (T1D) and type 2 diabetes (T2D) are at risk of falling, but the association with impaired postural control is unclear. Therefore, the aim was to investigate postural control by measuring the center of pressure (CoP) during quiet standing and to estimate the prevalence ratio (PR) of falls and the fear of falling among people with diabetes compared to controls. Methods: In a cross-sectional study, participants with T1D (n = 111) and T2D (n = 106) and controls without diabetes (n = 328) were included. Study procedures consisted of handgrip strength (HGS), vibration perception threshold (VPT), orthostatism, visual acuity, and postural control during quiet stance measured by CoP
Area (degree of body sway) and CoP
Velocity (speed of the body sway) with “eyes open,” “eyes closed” in combination with executive function tasks. A history of previous falls and fear of falling was collected by a questionnaire. CoP
Area and CoP
Velocity measurements were analyzed by using a multiple linear regression model. The PR of falls and the fear of falling were estimated by a Poisson regression model. Age, sex, BMI, previous falls, alcohol use, drug, HGS, VPT, orthostatism, episodes of hypoglycemia, and visual acuity were covariates in multiple adjusted analyses. Results: Significantly larger mean CoP
Area measures were observed for participants with T1D (p = 0.022) and T2D (0.002), whereas mean CoP
Velocity measures were only increased in participants with T2D (p = 0.027) vs. controls. Additionally, T1D and T2D participants had higher PRs for falls (p = 0.044, p = 0.014) and fear of falling (p = 0.006, p < 0.001) in the crude analyses, but the PRs reduced significantly when adjusted for mean CoP
Area and mean CoP
Velocity, respectively. Furthermore, multiple adjusted PRs were significantly higher than crude the analyses. Conclusion: Impaired postural control during quiet stance was seen in T1D and T2D compared with controls even in the occurrence of well-known risk factors. and correlated well with a higher prevalence of falls.
AB - Summary: New evidence points toward that impaired postural control judged by center of pressure measures during quiet stance is a predictor of falls in people with type 1 and type 2 diabetes—even in occurrence of well-known risk factors for falls. Introduction/aim: People with type 1 diabetes (T1D) and type 2 diabetes (T2D) are at risk of falling, but the association with impaired postural control is unclear. Therefore, the aim was to investigate postural control by measuring the center of pressure (CoP) during quiet standing and to estimate the prevalence ratio (PR) of falls and the fear of falling among people with diabetes compared to controls. Methods: In a cross-sectional study, participants with T1D (n = 111) and T2D (n = 106) and controls without diabetes (n = 328) were included. Study procedures consisted of handgrip strength (HGS), vibration perception threshold (VPT), orthostatism, visual acuity, and postural control during quiet stance measured by CoP
Area (degree of body sway) and CoP
Velocity (speed of the body sway) with “eyes open,” “eyes closed” in combination with executive function tasks. A history of previous falls and fear of falling was collected by a questionnaire. CoP
Area and CoP
Velocity measurements were analyzed by using a multiple linear regression model. The PR of falls and the fear of falling were estimated by a Poisson regression model. Age, sex, BMI, previous falls, alcohol use, drug, HGS, VPT, orthostatism, episodes of hypoglycemia, and visual acuity were covariates in multiple adjusted analyses. Results: Significantly larger mean CoP
Area measures were observed for participants with T1D (p = 0.022) and T2D (0.002), whereas mean CoP
Velocity measures were only increased in participants with T2D (p = 0.027) vs. controls. Additionally, T1D and T2D participants had higher PRs for falls (p = 0.044, p = 0.014) and fear of falling (p = 0.006, p < 0.001) in the crude analyses, but the PRs reduced significantly when adjusted for mean CoP
Area and mean CoP
Velocity, respectively. Furthermore, multiple adjusted PRs were significantly higher than crude the analyses. Conclusion: Impaired postural control during quiet stance was seen in T1D and T2D compared with controls even in the occurrence of well-known risk factors. and correlated well with a higher prevalence of falls.
KW - Center of pressure
KW - Falls
KW - Postural control
KW - Type 1 diabetes
KW - Type 2 diabetes
UR - http://www.scopus.com/inward/record.url?scp=85143571258&partnerID=8YFLogxK
U2 - 10.1007/s11657-022-01188-5
DO - 10.1007/s11657-022-01188-5
M3 - Journal article
C2 - 36482222
SN - 1862-3522
VL - 18
JO - Archives of Osteoporosis
JF - Archives of Osteoporosis
IS - 1
M1 - 6
ER -