Improved survival due to better renal outcomes in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) during the years 2000 to 2015 - a Danish nationwide study

Karl Emil Nelveg-Kristensen, Wladimir Szpirt, Nicholas Carlson, Jon Waast Gregersen, Elizabeth Krarup, Per Ivarsen, Christian Torp-Pedersen, Martin Egfjord

Publikation: Bidrag til tidsskriftKonferenceabstrakt i tidsskriftForskningpeer review

Abstrakt

INTRODUCTION: AAV (granulomatosis with polyangiitis and microscopic polyangiitis) carry significant risk of morbidity and mortality, notwithstanding adequate treatment. It has recently been suggested that incidence rates are increasing and risk of death declining, however, contemporary large-scale descriptive studies, with appropriate follow-up, have been challenged by the rare occurrence of these diseases. Accordingly, we examined these matters by use of Danish nationwide healthcare registries.METHODS: All patients with incident AAV, regardless of primary organ manifestation and severity were included by use of ICD10 diagnostic codes (positive predictive value of \gt; 90\ and grouped in five-year intervals (P1: 2000-2004, P2: 2005-2009, P3: 2010-1015). Absolute risk ratios (ARR) adjusted for age, sex and advanced disease severity (\gt;10 days of initial hospital stay), as well as cumulative incidences were assessed based on the Aalen-Johansen estimator in R version 3.5.0.
OriginalsprogEngelsk
ArtikelnummerFO057
TidsskriftNephrology, Dialysis, Transplantation
Vol/bind34
Udgave nummerSupplement_1
Antal sider1
ISSN0931-0509
DOI
StatusUdgivet - 1 jun. 2019
Begivenhed56th ERA-EDTA Congress - Budapest, Ungarn
Varighed: 13 jun. 201916 jun. 2019

Konference

Konference56th ERA-EDTA Congress
LandUngarn
ByBudapest
Periode13/06/201916/06/2019

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