Iodine deficiency influences thyroid autoimmunity in old age - A comparative population-based study

Stig Andersen; Finn Iversen; Steen Terpling; Klaus M Pedersen; Peter Gustenhoff; Peter Laurberg

doi:10.1016/j.maturitas.2011.10.001

Iodine deficiency influences thyroid autoimmunity in old age - A comparative population-based study

Stig Andersen, Finn Iversen, Steen Terpling, Klaus M Pedersen, Peter Gustenhoff, Peter Laurberg

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

25 Citationer (Scopus)

Abstract

OBJECTIVE: To assess thyroid autoimmunity among elderly people living in an area with low iodine intake compared to the sustained recommended iodine intake from a natural source, and to estimate the importance of migration. DESIGN AND SETTING: Iodine content of drinking water is highly different in the Danish towns Randers and Skagen. We collected blood and spot urine samples from 430 long-term Randers and Skagen dwellers aged 75-80 years, who filled in a questionnaire. We measured thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) in serum and iodine and creatinine in urine. RESULTS: Participation rate was 47% (n=212 (men/women 82/130) in Randers; 218 (84/134) in Skagen). Iodine deficiency prevailed in Randers while Skagen dwellers were iodine replete (median urinary iodine 74μg/24h vs. 184μg/24h, p

Originalsprog	Engelsk
Tidsskrift	Maturitas
Vol/bind	71
Udgave nummer	1
Sider (fra-til)	39-43
Antal sider	5
ISSN	0378-5122
DOI	https://doi.org/10.1016/j.maturitas.2011.10.001
Status	Udgivet - 2012
Udgivet eksternt	Ja

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10.1016/j.maturitas.2011.10.001

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Citationsformater

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abstract = "OBJECTIVE: To assess thyroid autoimmunity among elderly people living in an area with low iodine intake compared to the sustained recommended iodine intake from a natural source, and to estimate the importance of migration. DESIGN AND SETTING: Iodine content of drinking water is highly different in the Danish towns Randers and Skagen. We collected blood and spot urine samples from 430 long-term Randers and Skagen dwellers aged 75-80 years, who filled in a questionnaire. We measured thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) in serum and iodine and creatinine in urine. RESULTS: Participation rate was 47% (n=212 (men/women 82/130) in Randers; 218 (84/134) in Skagen). Iodine deficiency prevailed in Randers while Skagen dwellers were iodine replete (median urinary iodine 74μg/24h vs. 184μg/24h, p",

author = "Stig Andersen and Finn Iversen and Steen Terpling and Pedersen, {Klaus M} and Peter Gustenhoff and Peter Laurberg",

year = "2012",

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T1 - Iodine deficiency influences thyroid autoimmunity in old age - A comparative population-based study

AU - Andersen, Stig

AU - Iversen, Finn

AU - Terpling, Steen

AU - Pedersen, Klaus M

AU - Gustenhoff, Peter

AU - Laurberg, Peter

PY - 2012

Y1 - 2012

N2 - OBJECTIVE: To assess thyroid autoimmunity among elderly people living in an area with low iodine intake compared to the sustained recommended iodine intake from a natural source, and to estimate the importance of migration. DESIGN AND SETTING: Iodine content of drinking water is highly different in the Danish towns Randers and Skagen. We collected blood and spot urine samples from 430 long-term Randers and Skagen dwellers aged 75-80 years, who filled in a questionnaire. We measured thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) in serum and iodine and creatinine in urine. RESULTS: Participation rate was 47% (n=212 (men/women 82/130) in Randers; 218 (84/134) in Skagen). Iodine deficiency prevailed in Randers while Skagen dwellers were iodine replete (median urinary iodine 74μg/24h vs. 184μg/24h, p

AB - OBJECTIVE: To assess thyroid autoimmunity among elderly people living in an area with low iodine intake compared to the sustained recommended iodine intake from a natural source, and to estimate the importance of migration. DESIGN AND SETTING: Iodine content of drinking water is highly different in the Danish towns Randers and Skagen. We collected blood and spot urine samples from 430 long-term Randers and Skagen dwellers aged 75-80 years, who filled in a questionnaire. We measured thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TGAb) in serum and iodine and creatinine in urine. RESULTS: Participation rate was 47% (n=212 (men/women 82/130) in Randers; 218 (84/134) in Skagen). Iodine deficiency prevailed in Randers while Skagen dwellers were iodine replete (median urinary iodine 74μg/24h vs. 184μg/24h, p

U2 - 10.1016/j.maturitas.2011.10.001

DO - 10.1016/j.maturitas.2011.10.001

M3 - Journal article

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SP - 39

EP - 43

JO - Maturitas

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Iodine deficiency influences thyroid autoimmunity in old age - A comparative population-based study

Abstract

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