Simulations of thermally driven phase change phenomena of nanofluids are still in their infancy. Locating the gas–liquid interface location as precisely as possible is one of the primary problems in simulating such flows. The VOF method is the most applied interface description method in commercial and open-source CFD software to simulate nanofluids’ thermal phase change. Using the VOF method directs to inaccurate curvature calculation, which drives artificial flows (numerical non-physical velocities), especially in the vicinity of the gas–liquid interface. To recover accuracy in simulation results by VOF, a solver coupling VOF with the level-set interface description method can be used, in which the VOF is employed to capture the interface since it is a mass conserving method and the level-set is employed to calculate the curvature and physical quantities near the interface. We implemented the aforementioned coupled level-set and VOF (CLSVOF) method within the open-source OpenFOAMⓇ framework and conducted a comparative analysis between CLSVOF and VOF (the default interface capturing method) to demonstrate the CLSVOF method’s advantages and disadvantages in various phase change scenarios. Using experimental mathematical correlations from the literature, we consider the effect of nanoparticles on the base fluid. Results shows that the new inferred technique provides more precise curvature calculation and greater agreement between simulated and analytical/benchmark solutions, but at the expense of processing time.