Abstract
The risk of severe bleeding after liver biopsy is estimated to be 1:12,000 in patients with near normal coagulation (INR < 1,5 and platelet count > 60 billion /l). Beyond these limits, the risk is higher, but still uncertain. The Danish guidelines require INR > 1.5, platelet count < 40 billion /l and normal APTT. In some instances the risk of not knowing the histology is so high that a biopsy is considered even with a more disturbed coagulation. Vitamin K, freshly frozen plasma and recombinant activated factor VII may reduce the risk of bleeding in specific situations, but no firm recommendations can be given.
Udgivelsesdato: 2008-Nov-3
Udgivelsesdato: 2008-Nov-3
Originalsprog | Dansk |
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Vol/bind | 170 |
Sider (fra-til) | 3671-3 |
Antal sider | 2 |
ISSN | 0041-5782 |
Status | Udgivet - 2008 |
Udgivet eksternt | Ja |