Loperamid misbrugt for at opnå euforiserende effekt hos en ung kvinde

Signe Fiil, Terese Matthesen Kamronn, Tonny Studsgaard Petersen, Signe Livbjerg

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

Loperamide is an over-the-counter anti-diarrhoeal agent. In supratherapeutic doses, loperamide penetrates the blood-brain barrier, exceeds the efflux capacity of P-glycoprotein and binds to central opioid receptors. We report a case of a 33-year-old woman with a history of opioid abuse, who had a long-term excessive daily intake of loperamide in order to achieve a euphoric effect. Cardiac arrhythmias, respiratory depression and death have been reported in relation to excessive loperamide use.

Bidragets oversatte titelA young woman's loperamide abuse for the achievement of euphoric effect
OriginalsprogDansk
ArtikelnummerV11190650
TidsskriftUgeskrift for Laeger
Vol/bind182
Udgave nummer21
Sider (fra-til)2052-2053
ISSN0041-5782
StatusUdgivet - 16 mar. 2020

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