Making sense of phantom limb pain

Hunter R Schone*, Chris I Baker, Joel Katz, Lone Nikolajsen, Katleho Limakatso, Herta Flor, Tamar R Makin

*Kontaktforfatter

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)peer review

16 Citationer (Scopus)
46 Downloads (Pure)

Abstract

Phantom limb pain (PLP) impacts the majority of individuals who undergo limb amputation. The PLP experience is highly heterogenous in its quality, intensity, frequency and severity. This heterogeneity, combined with the low prevalence of amputation in the general population, has made it difficult to accumulate reliable data on PLP. Consequently, we lack consensus on PLP mechanisms, as well as effective treatment options. However, the wealth of new PLP research, over the past decade, provides a unique opportunity to re-evaluate some of the core assumptions underlying what we know about PLP and the rationale behind PLP treatments. The goal of this review is to help generate consensus in the field on how best to research PLP, from phenomenology to treatment. We highlight conceptual and methodological challenges in studying PLP, which have hindered progress on the topic and spawned disagreement in the field, and offer potential solutions to overcome these challenges. Our hope is that a constructive evaluation of the foundational knowledge underlying PLP research practices will enable more informed decisions when testing the efficacy of existing interventions and will guide the development of the next generation of PLP treatments.

OriginalsprogEngelsk
Artikelnummer328428
TidsskriftJournal of Neurology, Neurosurgery and Psychiatry
Vol/bind93
Udgave nummer8
Sider (fra-til)833-843
Antal sider11
ISSN0022-3050
DOI
StatusUdgivet - 1 aug. 2022

Bibliografisk note

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

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