Abstract
This article presents longitudinal 1H-MR Spectroscopy (1H-MRS) data from ventral hippocampus and in vivo diffusion MRI (dMRI) data of the brain from control and anhedonic rats. The1H-MRS and dMRI data were acquired using a 9.4 T preclinical imaging system. Before MRI experiments, animals were exposed to unpredictable chronic mild stress exposure for eight weeks and on the basis of a sucrose consumption test were identified as anhedonic and resilient. An age-matched group of animals, unexposed to the unpredictable chronic mild stress paradigm was considered as control. Data was acquired at the age of 18, 20 and 25 weeks in the anhedonic group and at the age of 18 and 22 weeks in the control group. This multimodal MRI data provides metabolic information of ventral hippocampus and dMRI based microstructural parameters of the brain.
| Originalsprog | Engelsk |
|---|---|
| Artikelnummer | 29 |
| Tidsskrift | Data |
| Vol/bind | 3 |
| Udgave nummer | 3 |
| ISSN | 2306-5729 |
| DOI | |
| Status | Udgivet - sep. 2018 |
| Udgivet eksternt | Ja |
Bibliografisk note
Funding Information:Lundbeck Foundation R83-A7548 and R253-2017-215. Danish Ministry of Science, Technology and Innovation’s University Investment Grant (MIND Lab, Grant no. 0601-01354B), and NIH 1R01EB012874-01. Danish Research Council’s Infrastructure program, the Velux Foundations, and the Department of Clinical Medicine, AU.
Funding Information:
Acknowledgments: Lundbeck Foundation R83-A7548 and R253-2017-215.Danish Ministry of Science, Technology and Innovation’s University Investment Grant (MIND Lab, Grant no. 0601-01354B), and NIH 1R01EB012874-01. Danish Research Council’s Infrastructure program, the Velux Foundations, and the Department of Clinical Medicine, AU.
Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.