Modelling the dependence structure of Y-STR haplotypes using graphical models

Mikkel Meyer Andersen, James Curran, Jacob de Zoete, Duncan Taylor, John Buckleton

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

5 Citationer (Scopus)

Abstrakt

Many methods have been suggested for evaluating the evidential value of a matching Y-chromosomal DNA
profile obtained from a biological stain associated with a crime scene and the Y-chromosomal DNA profile of a
suspect. Most of these methods are based on estimating the population frequency of the Y-profile. The common
independence assumption between loci for autosomal DNA profiles cannot be used for Y-chromosomal DNA
profiles. In this paper we reconsider the problem of population frequency estimation by application of Bayesian networks and the Chow-Liu algorithm to model dependencies between loci. We found that the method based on the Chow-Liu algorithm performs almost as well as the discrete Laplace method. We have also made comparisons to the independence model and we have demonstrated once again that the independence method foY-profiles cannot be supported.
OriginalsprogEngelsk
TidsskriftForensic Science International: Genetics
Vol/bind37
Sider (fra-til)29-36
Antal sider8
ISSN1872-4973
DOI
StatusUdgivet - 2018

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