Morphology and morphometry of the ulnar nerve in the forelimb of pigs

Felipe Rettore Andreis*, Benjamin Metcalfe, Taha Al Muhammadee Janjua, Valéria Paula Sassoli Fazan, Winnie Jensen, Suzan Meijs, Thomas Gomes Nørgaard Dos Santos Nielsen

*Kontaktforfatter

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

1 Citationer (Scopus)
4 Downloads (Pure)

Abstract

The knowledge of the morphology and morphometry of peripheral nerves is essential for developing neural interfaces and understanding nerve regeneration in basic and applied research. Currently, the most adopted animal model is the rat, even though recent studies have suggested that the neuroanatomy of large animal models is more comparable to humans. The present knowledge of the morphological structure of large animal models is limited; therefore, the present study aims to describe the morphological characteristics of the Ulnar Nerve (UN) in pigs. UN cross-sections were taken from seven Danish landrace pigs at three distinct locations: distal UN, proximal UN and at the dorsal cutaneous branch of the UN (DCBUN). The nerve diameter, fascicle diameter and number, number of fibres and fibre size were quantified. The UN diameter was larger in the proximal section compared to the distal segment and the DCBUN. The proximal branch also had a more significant number of fascicles (median: 15) than the distal (median: 10) and the DCBUN (median: 11) segments. Additionally, the mean fascicle diameter was smaller at the DCBUN (mean: 165 μm) than at the distal (mean: 197 μm) and proximal (mean: 199 μm) segments of the UN. Detailed knowledge of the microscopical structure of the UN in pigs is critical for further studies investigating neural interface designs and computational models of the peripheral nervous system.

OriginalsprogEngelsk
Artikelnummere12972
TidsskriftAnatomia, histologia, embryologia
Vol/bind53
Udgave nummer1
ISSN0340-2096
DOI
StatusUdgivet - jan. 2024

Bibliografisk note

© 2023 The Authors. Anatomia, Histologia, Embryologia published by Wiley-VCH GmbH.

Fingeraftryk

Dyk ned i forskningsemnerne om 'Morphology and morphometry of the ulnar nerve in the forelimb of pigs'. Sammen danner de et unikt fingeraftryk.

Citationsformater