Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia

Study Protocol for a Randomized, Controlled and Blinded Study

Bidragets oversatte titel: Musikterapi til behandling af skizofreniaptienters negative symptomer. Forskningsprotokol for et randomiseret, kontrlleret og blindet studie.

Inge Nygaard Pedersen, Lars Ole Bonde, Niels Hannibal, Jimmi Nielsen, Jørgen Aagaard, Lars Rye Bertelsen, Silvia Beatriz Jensen, René Ernst Nielsen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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Resumé

Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.

OriginalsprogEngelsk
Artikelnummer46
TidsskriftMedicines
Vol/bind6
Udgave nummer2
Antal sider15
DOI
StatusUdgivet - 1 apr. 2019

Emneord

  • schizofreni; negative symptomer; isolation; musikterapi behandling

Citer dette

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title = "Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia: Study Protocol for a Randomized, Controlled and Blinded Study",
abstract = "Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.",
keywords = "schizofreni; negative symptomer; isolation; musikterapi behandling",
author = "Pedersen, {Inge Nygaard} and Bonde, {Lars Ole} and Niels Hannibal and Jimmi Nielsen and J{\o}rgen Aagaard and Bertelsen, {Lars Rye} and Jensen, {Silvia Beatriz} and Nielsen, {Ren{\'e} Ernst}",
year = "2019",
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Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia : Study Protocol for a Randomized, Controlled and Blinded Study. / Pedersen, Inge Nygaard; Bonde, Lars Ole; Hannibal, Niels; Nielsen, Jimmi; Aagaard, Jørgen; Bertelsen, Lars Rye; Jensen, Silvia Beatriz; Nielsen, René Ernst.

I: Medicines, Bind 6, Nr. 2, 46, 01.04.2019.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

TY - JOUR

T1 - Music Therapy as Treatment of Negative Symptoms for Adult Patients Diagnosed with Schizophrenia

T2 - Study Protocol for a Randomized, Controlled and Blinded Study

AU - Pedersen, Inge Nygaard

AU - Bonde, Lars Ole

AU - Hannibal, Niels

AU - Nielsen, Jimmi

AU - Aagaard, Jørgen

AU - Bertelsen, Lars Rye

AU - Jensen, Silvia Beatriz

AU - Nielsen, René Ernst

PY - 2019/4/1

Y1 - 2019/4/1

N2 - Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.

AB - Abstract:Background: Three Cochrane Reviews show that music therapy has a positive effect on schizophrenia concerning general functioning and positive/negative symptoms. This study aims at replicating these results in the Danish health system, a requirement for recommendation in guidelines from the Danish National Board of Health. Methods/Design: The study is a randomized, controlled study with a blinded design aiming at including 90 participants, 18 – 65 years diagnosed according to ICD-10 with a schizophrenia diagnosis. Participants are randomized to one of two different music therapy activities for 25 weekly sessions. The study interventions are added to standard care. Outcome measures are rated at baseline, after 15 sessions and post therapy. A qualitative interview is performed at one month follow up at end of study. The primary outcome is a reduction in negative symptoms. The secondary outcome is progression in quality of life, alliance and psychosocial functioning. Results: As this study is still running the results are not yet available. Conclusion: The study will investigate the direct effects of music therapy on negative symptoms as part of schizophrenia in a blinded, randomized trial. If proven effective, music therapy can be added to the small treatment armamentarium of effective therapies for negative symptoms.

KW - schizofreni; negative symptomer; isolation; musikterapi behandling

U2 - 10.3390/medicines6020046

DO - 10.3390/medicines6020046

M3 - Journal article

VL - 6

JO - Medicines

JF - Medicines

SN - 2305-6320

IS - 2

M1 - 46

ER -