Nanocrystalline diamond films for biomedical applications

Cristian Pablo Pennisi, Maria Alcaide

Publikation: Bidrag til bog/antologi/rapport/konference proceedingBidrag til bog/antologiForskningpeer review

Resumé

Nanocrystalline diamond films, which comprise the so called nanocrystalline diamond (NCD) and ultrananocrystalline diamond (UNCD), represent a class of biomaterials possessing outstanding mechanical, tribological, and electrical properties, which include high surface smoothness, high corrosion resistance, chemical inertness, superior electrochemical behavior, biocompatibility, and nontoxicity. These properties have positioned the nanocrystalline diamond films as an attractive class of materials for a range of therapeutic and diagnostic applications in the biomedical field. Consequently, the interaction of nanocrystalline diamond films with biomolecules and cells has been focus of intense research during the last years, with many studies focused in tailoring the properties of the films for the control of their biological performance. In this chapter, the current knowledge regarding the biological performance of nanocrystalline diamond films is reviewed from an application-specific perspective, covering topics such as enhancement of cellular adhesion, anti-fouling coatings, non-thrombogenic surfaces, micropatterning of cells and proteins, and immobilization of biomolecules for bioassays. In order to better understand the terminology used in the literature, which is related to the fabrication and surface functionalization of this class of materials, some of the most common approaches for synthesis and modification of CVD diamond films is introduced. Although many challenges still remain, it is envisioned that the application of this unique class of materials will significantly influence the next generation of biomedical devices.
OriginalsprogEngelsk
TitelThe Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application
RedaktørerShunsheng Cao, Huijun Zhu
ForlagBentham Science Publishers
Publikationsdato2014
Sider70-100
Kapitel3
ISBN (Trykt)978-1-60805-877-8
ISBN (Elektronisk)978-1-60805-876-1
DOI
StatusUdgivet - 2014
NavnFrontiers in Biomaterials
Vol/bind1
ISSN2352-3921

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Diamond films
Diamond
Biomolecules
Bioassay
Biocompatible Materials
Terminology
Fouling
Biocompatibility
Corrosion resistance
Chemical vapor deposition
Membrane Proteins
Electric properties
Adhesion
Fabrication
Coatings
Mechanical properties

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    Citer dette

    Pennisi, C. P., & Alcaide, M. (2014). Nanocrystalline diamond films for biomedical applications. I S. Cao, & H. Zhu (red.), The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application (s. 70-100). Bentham Science Publishers. Frontiers in Biomaterials, Bind. 1 https://doi.org/10.2174/9781608058761114010006
    Pennisi, Cristian Pablo ; Alcaide, Maria. / Nanocrystalline diamond films for biomedical applications. The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application. red. / Shunsheng Cao ; Huijun Zhu. Bentham Science Publishers, 2014. s. 70-100 (Frontiers in Biomaterials, Bind 1).
    @inbook{da9b5569375b4a07a93b2d668c0d3590,
    title = "Nanocrystalline diamond films for biomedical applications",
    abstract = "Nanocrystalline diamond films, which comprise the so called nanocrystalline diamond (NCD) and ultrananocrystalline diamond (UNCD), represent a class of biomaterials possessing outstanding mechanical, tribological, and electrical properties, which include high surface smoothness, high corrosion resistance, chemical inertness, superior electrochemical behavior, biocompatibility, and nontoxicity. These properties have positioned the nanocrystalline diamond films as an attractive class of materials for a range of therapeutic and diagnostic applications in the biomedical field. Consequently, the interaction of nanocrystalline diamond films with biomolecules and cells has been focus of intense research during the last years, with many studies focused in tailoring the properties of the films for the control of their biological performance. In this chapter, the current knowledge regarding the biological performance of nanocrystalline diamond films is reviewed from an application-specific perspective, covering topics such as enhancement of cellular adhesion, anti-fouling coatings, non-thrombogenic surfaces, micropatterning of cells and proteins, and immobilization of biomolecules for bioassays. In order to better understand the terminology used in the literature, which is related to the fabrication and surface functionalization of this class of materials, some of the most common approaches for synthesis and modification of CVD diamond films is introduced. Although many challenges still remain, it is envisioned that the application of this unique class of materials will significantly influence the next generation of biomedical devices.",
    keywords = "Antifouling surfaces, Biocompatibility, Bionanotechnology, Biosensors, Blood Compatibility, Cell Adhesion, Cell Growth, Cell-material interface, Chemical Vapor Deposition, Diamond films",
    author = "Pennisi, {Cristian Pablo} and Maria Alcaide",
    year = "2014",
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    language = "English",
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    Pennisi, CP & Alcaide, M 2014, Nanocrystalline diamond films for biomedical applications. i S Cao & H Zhu (red), The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application. Bentham Science Publishers, Frontiers in Biomaterials, bind 1, s. 70-100. https://doi.org/10.2174/9781608058761114010006

    Nanocrystalline diamond films for biomedical applications. / Pennisi, Cristian Pablo; Alcaide, Maria.

    The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application. red. / Shunsheng Cao; Huijun Zhu. Bentham Science Publishers, 2014. s. 70-100.

    Publikation: Bidrag til bog/antologi/rapport/konference proceedingBidrag til bog/antologiForskningpeer review

    TY - CHAP

    T1 - Nanocrystalline diamond films for biomedical applications

    AU - Pennisi, Cristian Pablo

    AU - Alcaide, Maria

    PY - 2014

    Y1 - 2014

    N2 - Nanocrystalline diamond films, which comprise the so called nanocrystalline diamond (NCD) and ultrananocrystalline diamond (UNCD), represent a class of biomaterials possessing outstanding mechanical, tribological, and electrical properties, which include high surface smoothness, high corrosion resistance, chemical inertness, superior electrochemical behavior, biocompatibility, and nontoxicity. These properties have positioned the nanocrystalline diamond films as an attractive class of materials for a range of therapeutic and diagnostic applications in the biomedical field. Consequently, the interaction of nanocrystalline diamond films with biomolecules and cells has been focus of intense research during the last years, with many studies focused in tailoring the properties of the films for the control of their biological performance. In this chapter, the current knowledge regarding the biological performance of nanocrystalline diamond films is reviewed from an application-specific perspective, covering topics such as enhancement of cellular adhesion, anti-fouling coatings, non-thrombogenic surfaces, micropatterning of cells and proteins, and immobilization of biomolecules for bioassays. In order to better understand the terminology used in the literature, which is related to the fabrication and surface functionalization of this class of materials, some of the most common approaches for synthesis and modification of CVD diamond films is introduced. Although many challenges still remain, it is envisioned that the application of this unique class of materials will significantly influence the next generation of biomedical devices.

    AB - Nanocrystalline diamond films, which comprise the so called nanocrystalline diamond (NCD) and ultrananocrystalline diamond (UNCD), represent a class of biomaterials possessing outstanding mechanical, tribological, and electrical properties, which include high surface smoothness, high corrosion resistance, chemical inertness, superior electrochemical behavior, biocompatibility, and nontoxicity. These properties have positioned the nanocrystalline diamond films as an attractive class of materials for a range of therapeutic and diagnostic applications in the biomedical field. Consequently, the interaction of nanocrystalline diamond films with biomolecules and cells has been focus of intense research during the last years, with many studies focused in tailoring the properties of the films for the control of their biological performance. In this chapter, the current knowledge regarding the biological performance of nanocrystalline diamond films is reviewed from an application-specific perspective, covering topics such as enhancement of cellular adhesion, anti-fouling coatings, non-thrombogenic surfaces, micropatterning of cells and proteins, and immobilization of biomolecules for bioassays. In order to better understand the terminology used in the literature, which is related to the fabrication and surface functionalization of this class of materials, some of the most common approaches for synthesis and modification of CVD diamond films is introduced. Although many challenges still remain, it is envisioned that the application of this unique class of materials will significantly influence the next generation of biomedical devices.

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    KW - Chemical Vapor Deposition

    KW - Diamond films

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    DO - 10.2174/9781608058761114010006

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    SN - 978-1-60805-877-8

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    EP - 100

    BT - The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application

    A2 - Cao, Shunsheng

    A2 - Zhu, Huijun

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    ER -

    Pennisi CP, Alcaide M. Nanocrystalline diamond films for biomedical applications. I Cao S, Zhu H, red., The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application. Bentham Science Publishers. 2014. s. 70-100. (Frontiers in Biomaterials, Bind 1). https://doi.org/10.2174/9781608058761114010006