Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer

Sidse Bregendahl; Katrine Jøssing Emmertsen; Janne Fassov; Klaus Krogh; Jingbo Zhao; Hans Gregersen; Søren Laurberg

doi:10.1016/j.radonc.2013.07.004

Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer

Sidse Bregendahl, Katrine Jøssing Emmertsen, Janne Fassov, Klaus Krogh, Jingbo Zhao, Hans Gregersen, Søren Laurberg

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

44 Citationer (Scopus)

Abstract

Preoperative radiotherapy for rectal cancer has a detrimental effect on long-term anorectal function and quality of life, additional to that observed after rectal resection. The exact physiological mechanisms for the excess impairment remain unknown. We aimed to investigate neorectal and anal sphincter properties in patients treated with neoadjuvant therapy (NT) prior to total mesorectal excision (TME).

Originalsprog	Engelsk
Tidsskrift	Radiotherapy & Oncology
Vol/bind	108
Udgave nummer	2
Sider (fra-til)	331-336
Antal sider	6
ISSN	0167-8140
DOI	https://doi.org/10.1016/j.radonc.2013.07.004
Status	Udgivet - 7 aug. 2013

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10.1016/j.radonc.2013.07.004

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AU - Bregendahl, Sidse

AU - Emmertsen, Katrine Jøssing

AU - Fassov, Janne

AU - Krogh, Klaus

AU - Zhao, Jingbo

AU - Gregersen, Hans

AU - Laurberg, Søren

PY - 2013/8/7

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N2 - Preoperative radiotherapy for rectal cancer has a detrimental effect on long-term anorectal function and quality of life, additional to that observed after rectal resection. The exact physiological mechanisms for the excess impairment remain unknown. We aimed to investigate neorectal and anal sphincter properties in patients treated with neoadjuvant therapy (NT) prior to total mesorectal excision (TME).

AB - Preoperative radiotherapy for rectal cancer has a detrimental effect on long-term anorectal function and quality of life, additional to that observed after rectal resection. The exact physiological mechanisms for the excess impairment remain unknown. We aimed to investigate neorectal and anal sphincter properties in patients treated with neoadjuvant therapy (NT) prior to total mesorectal excision (TME).

U2 - 10.1016/j.radonc.2013.07.004

DO - 10.1016/j.radonc.2013.07.004

M3 - Journal article

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VL - 108

SP - 331

EP - 336

JO - Radiotherapy & Oncology

JF - Radiotherapy & Oncology

IS - 2

ER -

Neorectal hyposensitivity after neoadjuvant therapy for rectal cancer

Abstract

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