Neutrophil-lymphocyte-ratio distributions in a Danish population from general practice

Mikkel H Christiansen, Kristian Ø Barup, Mie H Samson

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Abstrakt

The neutrophil-lymphocyte ratio (NLR) is a novel biomarker, showing promising both diagnostic and prognostic capabilities. The aim of this study was to present NLR distributions in a Danish population from general practice (GP) and compare levels between patients from intensive care units (ICU) and GP. A register-based study was conducted using results from 31,966 blood samples from GP and ICU located in the admission area of Aarhus University Hospital, Denmark. Exclusion of samples with lymphocytes >40 × 10 9 /L, resulted in 28,582 samples from GP and 3,373 from ICU. Distributions for patients from GP with CRP <8 mg/L were age-dependent and were established for the following three age groups; 0–17 years [0.30:3.76], 18–75 years: [0.74:4.94], above 76 years: [0.89:8.80]. Patients from ICU had a significantly higher median NLR than patients from GP when stratified for CRP, [8.48 and 1.99 respectively]. This study describes for the first time the distributions of NLR in a large European population of GP patients.

OriginalsprogEngelsk
TidsskriftScandinavian Journal of Clinical & Laboratory Investigation
Vol/bind79
Udgave nummer1-2
Sider (fra-til)75–79
Antal sider5
ISSN0036-5513
DOI
StatusUdgivet - 15 jan. 2019

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