Abstract
In 11 pigs a standardized proximal ureteric obstruction was applied. The effect of the obstruction was examined three weeks later. In both the normal and the obstructed systems the pressure-volume relationship was exponential. Mean pelvic capacity increased from 6.5 ml. to 44.1 ml. (p <0.002). Mean intrapelvic baseline pressure increased from 10.0 to 16.8 cm. HO (p <0.02), and this parameter correlated positively to volume (r(s) = 0.79 -p <0.05). There was a slight decrease in the relative function of the obstructed kidney on renography (from 49% to 39% of the total renal function), but this was not significant. The decrease in function was correlated to the increase in capacity (r(s) = -0.69 -p <0.05). In this series renal deterioration occurred in the hydronephrotic kidneys, and at least in this model of acute ureteral obstruction there was no support for the theory that hydronephrotic transformation is a compensatory mechanism which protects the kidney when the upper urinary tract is obstructed.
Originalsprog | Engelsk |
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Tidsskrift | The Journal of Urology |
Vol/bind | 140 |
Sider (fra-til) | 848-852 |
Antal sider | 5 |
ISSN | 0022-5347 |
Status | Udgivet - 1 jan. 1988 |
Udgivet eksternt | Ja |