TY - JOUR
T1 - Predictors for splenectomy among patients with primary chronic immune thrombocytopenia: a population-based cohort study from Denmark
AU - Jensen, Annette Østergaard
AU - Nørgaard, Mette
AU - Engebjerg, Malene Cramer
AU - Farkas, Dora Körmendiné
AU - Fryzek, Jon P
AU - Zhao, Sean
AU - Sørensen, Henrik Toft
PY - 2011
Y1 - 2011
N2 - We conducted a nationwide cohort study of adult Danish patients with primary chronic immune thrombocytopenia (cITP) to examine selected patient and clinical characteristics as predictors for splenectomy. We analyzed data from the Danish National Patient Registry and patient medical records from 1996 to 2007. Using Cox regression analyses, we calculated incidence rate ratios (IRRs) and associated 95% confidence intervals (CI) for splenectomy. We included 371 adult cITP patients. Of these, 87 patients (23%) underwent a splenectomy during a median of 3.6 years of follow-up. The majority (84%) of cITP patients who underwent splenectomy had splenectomy within the first year after cITP diagnosis. Predictors for splenectomy included age
AB - We conducted a nationwide cohort study of adult Danish patients with primary chronic immune thrombocytopenia (cITP) to examine selected patient and clinical characteristics as predictors for splenectomy. We analyzed data from the Danish National Patient Registry and patient medical records from 1996 to 2007. Using Cox regression analyses, we calculated incidence rate ratios (IRRs) and associated 95% confidence intervals (CI) for splenectomy. We included 371 adult cITP patients. Of these, 87 patients (23%) underwent a splenectomy during a median of 3.6 years of follow-up. The majority (84%) of cITP patients who underwent splenectomy had splenectomy within the first year after cITP diagnosis. Predictors for splenectomy included age
U2 - 10.1007/s00277-010-1047-5
DO - 10.1007/s00277-010-1047-5
M3 - Journal article
SN - 0939-5555
VL - 90
SP - 207
EP - 212
JO - Annals of Hematology
JF - Annals of Hematology
ER -