Psychometric Properties of the Knee Osteoarthritis Pain Index

Scott G Ravyts; Timothy R Fleagle; Elena Staguhn; Daniel Scharfstein; Rachel V Aaron; Steven Paul Cohen; Robert W Hurley; Srinivasa N Raja; Jennifer Haythornthwaite; Lauren Allen; Robert R Edwards; Lars Arendt-Nielsen; Claudia M Campbell; Renan Castillo

doi:10.1093/pm/pnaf067

Psychometric Properties of the Knee Osteoarthritis Pain Index

Scott G Ravyts^*, Timothy R Fleagle, Elena Staguhn, Daniel Scharfstein, Rachel V Aaron, Steven Paul Cohen, Robert W Hurley, Srinivasa N Raja, Jennifer Haythornthwaite, Lauren Allen, Robert R Edwards, Lars Arendt-Nielsen, Claudia M Campbell, Renan Castillo

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Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Abstract

OBJECTIVES: The current study sought to evaluate the psychometric properties of a newly developed Knee OsteoArthritis Pain Index (KOAPI), derived from the Brief Pain Inventory (BPI), among individuals with knee osteoarthritis (KOA).

METHODS: This study consisted of secondary data analysis of two clinical trials. In study 1, 241 individuals with KOA were evaluated before total knee arthroplasty and six months post-surgery. In study 2, 37 individuals with KOA participated in a randomized, double-blind, placebo controlled, two-way crossover study in which they received either a COX-2 inhibitor followed by a placebo or a placebo followed by a COX-2 inhibitor. The KOAPI was derived from the BPI and included three BPI pain severity items (worst, average, current) and the BPI pain interference item related to pain when walking.

RESULTS: The KOAPI showed excellent model fit (CFI = 0.99; TFI: 0.98-0.99; RMSEA: 0.08-0.001), good reliability (Cronbach's alpha: 0.84-0.87) and high convergent validity with the Western Ontario and McMaster Universities Osteoarthritis Index (r = 0.66; 95% CI: 0.44, 0.81) and the Pain Catastrophizing Scale (r = 0.50; 95% CI: 0.39, 0.60).

CONCLUSIONS: Overall, the psychometric properties of the KOAPI were comparable or better than those produced by the original BPI pain severity subscale. The KOAPI may be a helpful screening and outcome measure for individuals with KOA that more closely captures symptoms which drive patients to seek clinical care.

Originalsprog	Engelsk
Tidsskrift	Pain Medicine
ISSN	1526-2375
DOI	https://doi.org/10.1093/pm/pnaf067
Status	E-pub ahead of print - 26 maj 2025

Bibliografisk note

© The Author(s) 2025. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected].

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10.1093/pm/pnaf067

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abstract = "OBJECTIVES: The current study sought to evaluate the psychometric properties of a newly developed Knee OsteoArthritis Pain Index (KOAPI), derived from the Brief Pain Inventory (BPI), among individuals with knee osteoarthritis (KOA).METHODS: This study consisted of secondary data analysis of two clinical trials. In study 1, 241 individuals with KOA were evaluated before total knee arthroplasty and six months post-surgery. In study 2, 37 individuals with KOA participated in a randomized, double-blind, placebo controlled, two-way crossover study in which they received either a COX-2 inhibitor followed by a placebo or a placebo followed by a COX-2 inhibitor. The KOAPI was derived from the BPI and included three BPI pain severity items (worst, average, current) and the BPI pain interference item related to pain when walking.RESULTS: The KOAPI showed excellent model fit (CFI = 0.99; TFI: 0.98-0.99; RMSEA: 0.08-0.001), good reliability (Cronbach's alpha: 0.84-0.87) and high convergent validity with the Western Ontario and McMaster Universities Osteoarthritis Index (r = 0.66; 95% CI: 0.44, 0.81) and the Pain Catastrophizing Scale (r = 0.50; 95% CI: 0.39, 0.60).CONCLUSIONS: Overall, the psychometric properties of the KOAPI were comparable or better than those produced by the original BPI pain severity subscale. The KOAPI may be a helpful screening and outcome measure for individuals with KOA that more closely captures symptoms which drive patients to seek clinical care.",

author = "Ravyts, {Scott G} and Fleagle, {Timothy R} and Elena Staguhn and Daniel Scharfstein and Aaron, {Rachel V} and Cohen, {Steven Paul} and Hurley, {Robert W} and Raja, {Srinivasa N} and Jennifer Haythornthwaite and Lauren Allen and Edwards, {Robert R} and Lars Arendt-Nielsen and Campbell, {Claudia M} and Renan Castillo",

note = "{\textcopyright} The Author(s) 2025. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected].",

year = "2025",

month = may,

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doi = "10.1093/pm/pnaf067",

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journal = "Pain Medicine",

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T1 - Psychometric Properties of the Knee Osteoarthritis Pain Index

AU - Ravyts, Scott G

AU - Fleagle, Timothy R

AU - Staguhn, Elena

AU - Scharfstein, Daniel

AU - Aaron, Rachel V

AU - Cohen, Steven Paul

AU - Hurley, Robert W

AU - Raja, Srinivasa N

AU - Haythornthwaite, Jennifer

AU - Allen, Lauren

AU - Edwards, Robert R

AU - Arendt-Nielsen, Lars

AU - Campbell, Claudia M

AU - Castillo, Renan

N1 - © The Author(s) 2025. Published by Oxford University Press on behalf of the American Academy of Pain Medicine. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected].

PY - 2025/5/26

Y1 - 2025/5/26

N2 - OBJECTIVES: The current study sought to evaluate the psychometric properties of a newly developed Knee OsteoArthritis Pain Index (KOAPI), derived from the Brief Pain Inventory (BPI), among individuals with knee osteoarthritis (KOA).METHODS: This study consisted of secondary data analysis of two clinical trials. In study 1, 241 individuals with KOA were evaluated before total knee arthroplasty and six months post-surgery. In study 2, 37 individuals with KOA participated in a randomized, double-blind, placebo controlled, two-way crossover study in which they received either a COX-2 inhibitor followed by a placebo or a placebo followed by a COX-2 inhibitor. The KOAPI was derived from the BPI and included three BPI pain severity items (worst, average, current) and the BPI pain interference item related to pain when walking.RESULTS: The KOAPI showed excellent model fit (CFI = 0.99; TFI: 0.98-0.99; RMSEA: 0.08-0.001), good reliability (Cronbach's alpha: 0.84-0.87) and high convergent validity with the Western Ontario and McMaster Universities Osteoarthritis Index (r = 0.66; 95% CI: 0.44, 0.81) and the Pain Catastrophizing Scale (r = 0.50; 95% CI: 0.39, 0.60).CONCLUSIONS: Overall, the psychometric properties of the KOAPI were comparable or better than those produced by the original BPI pain severity subscale. The KOAPI may be a helpful screening and outcome measure for individuals with KOA that more closely captures symptoms which drive patients to seek clinical care.

AB - OBJECTIVES: The current study sought to evaluate the psychometric properties of a newly developed Knee OsteoArthritis Pain Index (KOAPI), derived from the Brief Pain Inventory (BPI), among individuals with knee osteoarthritis (KOA).METHODS: This study consisted of secondary data analysis of two clinical trials. In study 1, 241 individuals with KOA were evaluated before total knee arthroplasty and six months post-surgery. In study 2, 37 individuals with KOA participated in a randomized, double-blind, placebo controlled, two-way crossover study in which they received either a COX-2 inhibitor followed by a placebo or a placebo followed by a COX-2 inhibitor. The KOAPI was derived from the BPI and included three BPI pain severity items (worst, average, current) and the BPI pain interference item related to pain when walking.RESULTS: The KOAPI showed excellent model fit (CFI = 0.99; TFI: 0.98-0.99; RMSEA: 0.08-0.001), good reliability (Cronbach's alpha: 0.84-0.87) and high convergent validity with the Western Ontario and McMaster Universities Osteoarthritis Index (r = 0.66; 95% CI: 0.44, 0.81) and the Pain Catastrophizing Scale (r = 0.50; 95% CI: 0.39, 0.60).CONCLUSIONS: Overall, the psychometric properties of the KOAPI were comparable or better than those produced by the original BPI pain severity subscale. The KOAPI may be a helpful screening and outcome measure for individuals with KOA that more closely captures symptoms which drive patients to seek clinical care.

U2 - 10.1093/pm/pnaf067

DO - 10.1093/pm/pnaf067

M3 - Journal article

C2 - 40418215

SN - 1526-2375

JO - Pain Medicine

JF - Pain Medicine

ER -

Psychometric Properties of the Knee Osteoarthritis Pain Index

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