TY - JOUR
T1 - Renal Disease and Atrial Fibrillation
AU - Stefil, Maria
AU - Nabrdalik, Katarzyna
AU - Lip, Gregory Y.H.
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Incidence and prevalence of atrial fibrillation (AF) and chronic kidney disease are increasing, and the two conditions commonly coexist. Renal impairment further increases the risk of ischemic stroke and systemic thromboembolism in patients with AF but also paradoxically predisposes to bleeding. Renal function should be monitored closely in patients with AF requiring oral anticoagulation therapy, particularly those receiving direct oral anticoagulants. Vitamin K antagonists can be used as part of a dose-adjusted anticoagulation regimen in patients with mild to moderate renal dysfunction. Dialysis-dependent patients taking vitamin K antagonists are at increased risk of sustaining major hemorrhage.
AB - Incidence and prevalence of atrial fibrillation (AF) and chronic kidney disease are increasing, and the two conditions commonly coexist. Renal impairment further increases the risk of ischemic stroke and systemic thromboembolism in patients with AF but also paradoxically predisposes to bleeding. Renal function should be monitored closely in patients with AF requiring oral anticoagulation therapy, particularly those receiving direct oral anticoagulants. Vitamin K antagonists can be used as part of a dose-adjusted anticoagulation regimen in patients with mild to moderate renal dysfunction. Dialysis-dependent patients taking vitamin K antagonists are at increased risk of sustaining major hemorrhage.
KW - Atrial fibrillation
KW - Chronic kidney disease
KW - Management
KW - Risk stratification
UR - http://www.scopus.com/inward/record.url?scp=85099166184&partnerID=8YFLogxK
U2 - 10.1016/j.ccep.2020.11.001
DO - 10.1016/j.ccep.2020.11.001
M3 - Review article
AN - SCOPUS:85099166184
SN - 1877-9182
VL - 13
SP - 95
EP - 112
JO - Cardiac Electrophysiology Clinics
JF - Cardiac Electrophysiology Clinics
IS - 1
ER -