Safety of Intravenous and Inhalation Anesthetics

Luiz Fernando Ferrari; Lars Arendt-Nielsen

doi:10.1007/978-3-030-73317-9_68-1

Safety of Intravenous and Inhalation Anesthetics

Luiz Fernando Ferrari, Lars Arendt-Nielsen

Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Bidrag til bog/antologi › Forskning › peer review

Abstract

Here is presented, in chronological order, the studies that established the standards and determined the parameters currently considered for the safe use of anesthetic agents administered by intravenous or inhalation routes. The methods used in the experimental settings, as well as the modifications in the protocols to adapt to different clinical conditions, are described and discussed; The pharmacological criteria and the impact of these anesthetics on the cardiovascular and pulmonary systems are highlighted. However, additional information regarding the mechanisms of action of such agents is still needed, which would improve their use in terms of safety and efficacy.

Originalsprog	Engelsk
Titel	Drug Discovery and Evaluation : Safety and Pharmacokinetic Assays
Redaktører	Franz J. Hock, Michael R. Gralinski, Michael K. Pugsley
Forlag	Springer
Publikationsdato	2 dec. 2022
Sider	1-9
ISBN (Trykt)	978-3-030-73317-9
ISBN (Elektronisk)	978-3-030-73317-9
DOI	https://doi.org/10.1007/978-3-030-73317-9_68-1
Status	Udgivet - 2 dec. 2022

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10.1007/978-3-030-73317-9_68-1

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abstract = "Here is presented, in chronological order, the studies that established the standards and determined the parameters currently considered for the safe use of anesthetic agents administered by intravenous or inhalation routes. The methods used in the experimental settings, as well as the modifications in the protocols to adapt to different clinical conditions, are described and discussed; The pharmacological criteria and the impact of these anesthetics on the cardiovascular and pulmonary systems are highlighted. However, additional information regarding the mechanisms of action of such agents is still needed, which would improve their use in terms of safety and efficacy.",

keywords = "Intravenous anesthetics, Inhalation anesthetics, Anesthetics safety, Anesthetic safety assessment, Anesthetic Potency, Minimum Alveolar Concentration",

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Safety of Intravenous and Inhalation Anesthetics. / Ferrari, Luiz Fernando; Arendt-Nielsen, Lars.
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays. red. / Franz J. Hock; Michael R. Gralinski; Michael K. Pugsley. Springer, 2022. s. 1-9.

Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Bidrag til bog/antologi › Forskning › peer review

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KW - Anesthetic safety assessment

KW - Anesthetic Potency

KW - Minimum Alveolar Concentration

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Safety of Intravenous and Inhalation Anesthetics

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