Abstract
The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.
| Originalsprog | Engelsk |
|---|---|
| IPC | C40B 40/ 02 A I |
| Patentnummer | US2009203542 |
| Land/Område | Danmark |
| Prioritetsdato | 07/10/2008 |
| Prioritetsnummer | US20080246741 |
| Status | Udgivet - 13 aug. 2009 |
| Udgivet eksternt | Ja |