Abstract
The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.
| Originalsprog | Engelsk |
|---|---|
| IPC | C40B 40/ 02 A I |
| Patentnummer | GB2361237 |
| Land/Område | Danmark |
| Prioritetsdato | 13/05/1999 |
| Prioritetsnummer | WO1999GB01526 |
| Status | Udgivet - 17 okt. 2001 |