Self-management of oral anticoagulant therapy in two centers: 11.000 patient-years of follow-up

Hanna Nilsson, E Grove, Torben Bjerregaard Larsen, M Maegaard, TD Christensen

Publikation: Konferencebidrag uden forlag/tidsskriftKonferenceabstrakt til konferenceForskningpeer review

Abstrakt

Self-management of oral anticoagulant therapy in two centers:
11.000 patient-years of follow-up
H Nilsson1,2,3, EL Grove2, TB Larsen3, M Maegaard1, TD Christensen1
1Department of Cardiothoracic and Vascular Surgery & Institute of Clinical Medicine,
Aarhus University Hospital, Aarhus; 2Department of Cardiology, Aarhus University
Hospital, Aarhus; 3Department of Cardiology, Aalborg Hospital & Department of Health
Science and Technology, Aalborg University, Aalborg, Denmark
haana_86@hotmail.com
Objectives: Patient-self-management (PSM) of oral anticoagulant therapy with
vitamin K antagonists have demonstrated efficacy in randomized clinical trials.
An important question remains about its clinical effectiveness. We hypothesized
that implementation of PSM in everyday clinical practice could improve the
quality of treatment. The aim of this study was to evaluate the effectiveness of
PSM in everyday clinical practice.
Materials and methods: A case-series study including all patients who had
passed an exam in PSM in the period 1995-2012 at Aarhus University Hospital or
Aalborg University Hospital, including 2200 patients and 11000 patient-years in
total. The effectiveness was measured using the endpoints: all-cause mortality,
major thromboembolism and bleeding events, percentage of time within
therapeutic International Normalized Ratio (INR) target range (TTR) and variance
of the INR value. Patient data was obtained from two databases in the two
centers, where all data had been prospectively registered.
Results: Results are pending but baseline characteristics (age, gender, indication
for anticoagulant therapy) and data on all-cause mortality, major
thromboembolism and bleeding events, TTR, INR-variance will be presented at
the meeting.
Conclusions: We hope to find a good quality of treatment. Further analysis will
be commenced by applying a control group and using data from national
databases.
OriginalsprogEngelsk
Publikationsdato2013
StatusUdgivet - 2013
BegivenhedThe Scandinavian Society for Research in Cardiothoracic Surgery - Geilo, Norge
Varighed: 7 feb. 20137 feb. 2013

Konference

KonferenceThe Scandinavian Society for Research in Cardiothoracic Surgery
LandNorge
ByGeilo
Periode07/02/201307/02/2013

Citationsformater

Nilsson, H., Grove, E., Larsen, T. B., Maegaard, M., & Christensen, TD. (2013). Self-management of oral anticoagulant therapy in two centers: 11.000 patient-years of follow-up. Abstract fra The Scandinavian Society for Research in Cardiothoracic Surgery, Geilo, Norge.