Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking

Andrew James Thomas Stevenson; Svend Sparre Geertsen; Jens Bo Nielsen; Natalie Mrachacz-Kersting

doi:10.1007/978-3-319-46669-9_167

Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking

Andrew James Thomas Stevenson, Svend Sparre Geertsen, Jens Bo Nielsen, Natalie Mrachacz-Kersting

Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceartikel i proceeding › Forskning › peer review

Abstrakt

In humans, short-latency crossed spinal inhibitory reflexes are elicited in the contralateral soleus (cSOL) muscle following stimulation of the ipsilateral posterior tibial nerve (iPTN). To date, the spinal interneurons mediating the cSOL inhibition are unknown. This study investigated whether the Ia inhibitory interneurons in the disynaptic reciprocal inhibition pathway mediate the short-latency cSOL inhibition. Following combined stimulation of the iPTN and the contralateral common peroneal nerve (cCPN), we quantified the spatial facilitation of the ongoing electromyography (EMG; Experiment 1) or the test H-reflex (Experiment 2) in the cSOL during walking. There was a significant increase in the cSOL inhibition when the two stimuli were elicited in combination compared to that expected from the algebraic sum of the two if elicited separately. It is therefore likely that the Ia inhibitory interneurons in the disynaptic reciprocal inhibitory pathway contribute to the short-latency cSOL inhibitory reflex.

Originalsprog	Engelsk
Titel	Converging Clinical and Engineering Research on Neurorehabilitation II : Proceedings of the 3rd International Conference on NeuroRehabilitation, ICNR2016, 18-21 October 2016, Segovia, Spain
Redaktører	Jaime Ibáñez, José González-Vargas, José María Azorín, Metin Akay, José Luis Pons
Forlag	Springer
Publikationsdato	2017
Sider	1031-1036
ISBN (Trykt)	978-3-319-46668-2
ISBN (Elektronisk)	978-3-319-46669-9
DOI	https://doi.org/10.1007/978-3-319-46669-9_167
Status	Udgivet - 2017
Begivenhed	International Conference on NeuroRehabilitation, ICNR - Segovia, Spanien Varighed: 18 okt. 2016 → 21 okt. 2016 Konferencens nummer: 3

Konference

Konference	International Conference on NeuroRehabilitation, ICNR
Nummer	3
Land/Område	Spanien
By	Segovia
Periode	18/10/2016 → 21/10/2016

Navn	Biosystems and Biorobotics
Nummer	15
ISSN	2195-3562

Adgang til dokumentet

10.1007/978-3-319-46669-9_167

Citationsformater

Stevenson, A. J. T., Geertsen, S. S., Nielsen, J. B., & Mrachacz-Kersting, N. (2017). Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking. I J. Ibáñez, J. González-Vargas, J. M. Azorín, M. Akay, & J. L. Pons (red.), Converging Clinical and Engineering Research on Neurorehabilitation II: Proceedings of the 3rd International Conference on NeuroRehabilitation, ICNR2016, 18-21 October 2016, Segovia, Spain (s. 1031-1036). Springer. Biosystems and Biorobotics Nr. 15 https://doi.org/10.1007/978-3-319-46669-9_167

Stevenson, Andrew James Thomas ; Geertsen, Svend Sparre ; Nielsen, Jens Bo ; Mrachacz-Kersting, Natalie. / Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking. Converging Clinical and Engineering Research on Neurorehabilitation II: Proceedings of the 3rd International Conference on NeuroRehabilitation, ICNR2016, 18-21 October 2016, Segovia, Spain. red. / Jaime Ibáñez ; José González-Vargas ; José María Azorín ; Metin Akay ; José Luis Pons. Springer, 2017. s. 1031-1036 (Biosystems and Biorobotics; Nr. 15).

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title = "Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking",

abstract = "In humans, short-latency crossed spinal inhibitory reflexes are elicited in the contralateral soleus (cSOL) muscle following stimulation of the ipsilateral posterior tibial nerve (iPTN). To date, the spinal interneurons mediating the cSOL inhibition are unknown. This study investigated whether the Ia inhibitory interneurons in the disynaptic reciprocal inhibition pathway mediate the short-latency cSOL inhibition. Following combined stimulation of the iPTN and the contralateral common peroneal nerve (cCPN), we quantified the spatial facilitation of the ongoing electromyography (EMG; Experiment 1) or the test H-reflex (Experiment 2) in the cSOL during walking. There was a significant increase in the cSOL inhibition when the two stimuli were elicited in combination compared to that expected from the algebraic sum of the two if elicited separately. It is therefore likely that the Ia inhibitory interneurons in the disynaptic reciprocal inhibitory pathway contribute to the short-latency cSOL inhibitory reflex.",

author = "Stevenson, {Andrew James Thomas} and Geertsen, {Svend Sparre} and Nielsen, {Jens Bo} and Natalie Mrachacz-Kersting",

year = "2017",

doi = "10.1007/978-3-319-46669-9_167",

language = "English",

isbn = "978-3-319-46668-2",

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editor = "Jaime Ib{\'a}{\~n}ez and Jos{\'e} Gonz{\'a}lez-Vargas and Azor{\'i}n, {Jos{\'e} Mar{\'i}a} and Metin Akay and Pons, {Jos{\'e} Luis}",

booktitle = "Converging Clinical and Engineering Research on Neurorehabilitation II",

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Stevenson, AJT, Geertsen, SS, Nielsen, JB & Mrachacz-Kersting, N 2017, Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking. i J Ibáñez, J González-Vargas, JM Azorín, M Akay & JL Pons (red), Converging Clinical and Engineering Research on Neurorehabilitation II: Proceedings of the 3rd International Conference on NeuroRehabilitation, ICNR2016, 18-21 October 2016, Segovia, Spain. Springer, Biosystems and Biorobotics, nr. 15, s. 1031-1036, International Conference on NeuroRehabilitation, ICNR, Segovia, Spanien, 18/10/2016. https://doi.org/10.1007/978-3-319-46669-9_167

Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking. / Stevenson, Andrew James Thomas; Geertsen, Svend Sparre; Nielsen, Jens Bo; Mrachacz-Kersting, Natalie.

Converging Clinical and Engineering Research on Neurorehabilitation II: Proceedings of the 3rd International Conference on NeuroRehabilitation, ICNR2016, 18-21 October 2016, Segovia, Spain. red. / Jaime Ibáñez; José González-Vargas; José María Azorín; Metin Akay; José Luis Pons. Springer, 2017. s. 1031-1036 (Biosystems and Biorobotics; Nr. 15).

Publikation: Bidrag til bog/antologi/rapport/konference proceeding › Konferenceartikel i proceeding › Forskning › peer review

TY - GEN

T1 - Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking

AU - Stevenson, Andrew James Thomas

AU - Geertsen, Svend Sparre

AU - Nielsen, Jens Bo

AU - Mrachacz-Kersting, Natalie

N1 - Conference code: 3

PY - 2017

Y1 - 2017

N2 - In humans, short-latency crossed spinal inhibitory reflexes are elicited in the contralateral soleus (cSOL) muscle following stimulation of the ipsilateral posterior tibial nerve (iPTN). To date, the spinal interneurons mediating the cSOL inhibition are unknown. This study investigated whether the Ia inhibitory interneurons in the disynaptic reciprocal inhibition pathway mediate the short-latency cSOL inhibition. Following combined stimulation of the iPTN and the contralateral common peroneal nerve (cCPN), we quantified the spatial facilitation of the ongoing electromyography (EMG; Experiment 1) or the test H-reflex (Experiment 2) in the cSOL during walking. There was a significant increase in the cSOL inhibition when the two stimuli were elicited in combination compared to that expected from the algebraic sum of the two if elicited separately. It is therefore likely that the Ia inhibitory interneurons in the disynaptic reciprocal inhibitory pathway contribute to the short-latency cSOL inhibitory reflex.

AB - In humans, short-latency crossed spinal inhibitory reflexes are elicited in the contralateral soleus (cSOL) muscle following stimulation of the ipsilateral posterior tibial nerve (iPTN). To date, the spinal interneurons mediating the cSOL inhibition are unknown. This study investigated whether the Ia inhibitory interneurons in the disynaptic reciprocal inhibition pathway mediate the short-latency cSOL inhibition. Following combined stimulation of the iPTN and the contralateral common peroneal nerve (cCPN), we quantified the spatial facilitation of the ongoing electromyography (EMG; Experiment 1) or the test H-reflex (Experiment 2) in the cSOL during walking. There was a significant increase in the cSOL inhibition when the two stimuli were elicited in combination compared to that expected from the algebraic sum of the two if elicited separately. It is therefore likely that the Ia inhibitory interneurons in the disynaptic reciprocal inhibitory pathway contribute to the short-latency cSOL inhibitory reflex.

U2 - 10.1007/978-3-319-46669-9_167

DO - 10.1007/978-3-319-46669-9_167

M3 - Article in proceeding

SN - 978-3-319-46668-2

T3 - Biosystems and Biorobotics

SP - 1031

EP - 1036

BT - Converging Clinical and Engineering Research on Neurorehabilitation II

A2 - Ibáñez, Jaime

A2 - González-Vargas, José

A2 - Azorín, José María

A2 - Akay, Metin

A2 - Pons, José Luis

PB - Springer

Y2 - 18 October 2016 through 21 October 2016

ER -

Stevenson AJT, Geertsen SS, Nielsen JB, Mrachacz-Kersting N. Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking. I Ibáñez J, González-Vargas J, Azorín JM, Akay M, Pons JL, red., Converging Clinical and Engineering Research on Neurorehabilitation II: Proceedings of the 3rd International Conference on NeuroRehabilitation, ICNR2016, 18-21 October 2016, Segovia, Spain. Springer. 2017. s. 1031-1036. (Biosystems and Biorobotics; Nr. 15). https://doi.org/10.1007/978-3-319-46669-9_167

Spatial facilitation of reciprocal inhibition and crossed inhibitory responses to soleus motoneurons during walking

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