Abstract
Recent reports suggest beneficial effects of statin treatment on risk of venous thromboembolism (VTE). This review studies the existing literature on statins and VTE: one meta-analysis, one randomized controlled trial, four cohort studies and eight case-control studies. The hypothesis of a risk reducing effect of statins on recurrent VTE is supported, but the included studies are heterogeneous; and there is a risk of uncontrolled confounding. Randomized clinical trials aimed at clarifying whether statins can prevent recurrent VTE or not are warranted.
Originalsprog | Dansk |
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Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 173 |
Udgave nummer | 22 |
Sider (fra-til) | 1558-1563 |
Antal sider | 6 |
ISSN | 0041-5782 |
Status | Udgivet - 30 maj 2011 |
Udgivet eksternt | Ja |
Emneord
- Anticholesteremic Agents
- Evidence-Based Medicine
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Randomized Controlled Trials as Topic
- Recurrence
- Venous Thromboembolism