Statiner kan måske reducere risikoen for venøs tromboemboli

Anne Pernille Toft-Petersen, Reimar Wernich Thomsen, Erik Berg Schmidt, Torben Bjerregaard Larsen

Publikation: Bidrag til tidsskriftReview (oversigtsartikel)peer review

Abstract

Recent reports suggest beneficial effects of statin treatment on risk of venous thromboembolism (VTE). This review studies the existing literature on statins and VTE: one meta-analysis, one randomized controlled trial, four cohort studies and eight case-control studies. The hypothesis of a risk reducing effect of statins on recurrent VTE is supported, but the included studies are heterogeneous; and there is a risk of uncontrolled confounding. Randomized clinical trials aimed at clarifying whether statins can prevent recurrent VTE or not are warranted.
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind173
Udgave nummer22
Sider (fra-til)1558-1563
Antal sider6
ISSN0041-5782
StatusUdgivet - 30 maj 2011
Udgivet eksterntJa

Emneord

  • Anticholesteremic Agents
  • Evidence-Based Medicine
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Randomized Controlled Trials as Topic
  • Recurrence
  • Venous Thromboembolism

Citationsformater