TY - JOUR
T1 - Temporal changes in survival among adult patients with acute myeloid leukaemia in the period 2000-2016
T2 - a Danish population-based study
AU - Jakobsen, Lasse Hjort
AU - Roug, Anne Stidsholt
AU - Øvlisen, Andreas Kiesbye
AU - Marcher, Claus Werenberg
AU - Ommen, Hans Beier
AU - Theilgaard-Mönch, Kim
AU - Møller, Peter
AU - Schöllkopf, Claudia
AU - Kristensen, Daniel
AU - Naur, Therese Maria Henriette
AU - Bøgsted, Martin
AU - El-Galaly, Tarec Christoffer
AU - Severinsen, Marianne Tang
N1 - © 2020 British Society for Haematology and John Wiley & Sons Ltd.
PY - 2021/5
Y1 - 2021/5
N2 - In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50-75 years and a small absolute increase in those aged >75 years.
AB - In the present study, we quantify the progress in overall survival (OS) during the period 2000-2016 among Danish patients with acute myeloid leukaemia (AML). This population-based study, including 3820 adult patients with AML, demonstrates a significantly improved OS over time with the 2-year age-standardised OS increasing from 22% in 2002 to 31% in 2016. The improvement in OS was exclusively seen in patients with AML aged ≥50 years, with absolute improvements in 2-year OS from 2002 to 2016 of ≥10% among patients aged 50-75 years and a small absolute increase in those aged >75 years.
KW - acute myeloid leukaemia
KW - real-world patients
KW - temporal survival
UR - http://www.scopus.com/inward/record.url?scp=85096676350&partnerID=8YFLogxK
U2 - 10.1111/bjh.17213
DO - 10.1111/bjh.17213
M3 - Journal article
C2 - 33222154
SN - 0007-1048
VL - 193
SP - 482
EP - 487
JO - British Journal of Haematology
JF - British Journal of Haematology
IS - 3
ER -