TY - JOUR
T1 - Testing HER2 in Breast Cancer: A Comparative Study on BRISH, FISH, and IHC
AU - Brügmann, Anja
AU - Lelkaitis, Giedrius
AU - Nielsen, Søren
AU - Jensen, Kirsten Gadgaard
AU - Jensen, Vibeke Eleonora Dagmar
PY - 2011/5/1
Y1 - 2011/5/1
N2 - : New brightfield in-situ hybridization (BRISH) methods based on the cohybridization of probes to the HER2 gene and chromosome 17 centromere have been developed and provide a promising alternative to fluorescence in-situ hybridization (FISH). The aim of this correlation study was to test HER2 status in primary breast carcinomas with 2 BRISH methods, FISH, and 2 immunohistochemical assays using tissue microarray technology.
AB - : New brightfield in-situ hybridization (BRISH) methods based on the cohybridization of probes to the HER2 gene and chromosome 17 centromere have been developed and provide a promising alternative to fluorescence in-situ hybridization (FISH). The aim of this correlation study was to test HER2 status in primary breast carcinomas with 2 BRISH methods, FISH, and 2 immunohistochemical assays using tissue microarray technology.
U2 - 10.1097/PAI.0b013e3181f7118e
DO - 10.1097/PAI.0b013e3181f7118e
M3 - Journal article
SN - 1541-2016
VL - 19
SP - 203
EP - 211
JO - Applied Immunohistochemistry & Molecular Morphology
JF - Applied Immunohistochemistry & Molecular Morphology
ER -