Projects per year
Organisation profile
Organisation profile
Research centre name:
Centre for Neuroplasticity and Pain
Date of establishment and expected operational period of the centre:
2015-2025
Initials of research centre:
CNAP
Head of research centre:
Prof. Thomas Graven-Nielsen
Participants and partners?
CNAP consists of researchers from four different research groups at AAU:
- Neural Engineering and Neurophysiology
- Integrative Neuroscience
- Pain and Motor System Plasticity
- Translational Pain Biomarkers
Who are we?
Center for Neuroplasticity and Pain (CNAP) is a Center of Excellence at the Department of Health Science and Technology, funded by the Danish National Research Foundation in the period 2015-2025.
What are our fundamental goals/objectives?
The ambition of CNAP is to identify and modulate key features of human pain neuroplasticity. We keenly believe that this can be achieved through a systematic engineering approach, including provoking, probing and modulation of the dynamic neuroplastic properties of the pain system.
Our research – what we do?
CNAP applies a basic research approach where new advanced biomedical provocation and probing platforms are being discovered and applied to study novel aspects of the human pain neuroplasticity. When an injury results in acute pain, the nervous system undergoes an adaptive neuroplastic response resulting in an increase in sensitivity. After some time, the pain neuroplasticity is normalized as the injury heals. In some cases, such neuroplastic processes fail to normalize during convalescence, and acute pain develops into chronic pain with hypersensitivity. The continuing pain after injury resolution may be caused by maladaptive pain neuroplasticity. In contrast, advantageous neuroplasticity permits the nervous system to cope with challenges such as maladaptive pain neuroplasticity to help returning to a pain-free state.
Interdisciplinary, international cooperation, and research training combined with the capacity of leading researchers is the core research philosophy of CNAP. Thus, all our research groups are highly interdisciplinary and include experts within e.g. biomedical engineering, neuropsychology, pharmacology, biophysics, and medicine. To secure international excellence, CNAP strives for an equal distribution between genders and between national and international staff.
How does our research contribute to societal health challenges?
Chronic pain is a key societal challenge: it affects one out of five adults, and is generally poorly treated. Through the research we conduct at CNAP, we contribute to improving pain treatments.
How are we funded?
CNAP is funded by the Danish National Research Foundation (DNRF121) and by the European Union’s Horizon 2020 research and innovation programme (Marie Skłodowska-Curie grant agreement No 754465).
Who are our key collaborators?
CNAP cooperates with several renowned national and international researchers. In addition, a number of international collaborators are embedded within CNAP and participate actively in the centre’s activities.
Collaborations from the last five years
Profiles
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Giulia Erica Aliotta
- The Faculty of Medicine - Post.Doc.
- Department of Health Science and Technology - Post.Doc.
- Translational Biomarkers in Pain and Precision Medicine - Post.Doc.
- Center for Neuroplasticity and Pain
Person: VIP
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Trine Andresen
- The Faculty of Medicine - Post.Doc.
- Department of Health Science and Technology - Post.Doc.
- Integrative Neuroscience - Post.Doc.
- Pain and Motor System Plasticity - Post.Doc.
- Center for Neuroplasticity and Pain
Person: VIP
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C19 Symptom Mapping
Boudreau, S., Bøggild, H., Duroux, M. & Holden, S.
26/03/2020 → …
Project: Research
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Investigation of temporal and spatial integration of pain information in the nociceptive system
Rujoie, A.
01/11/2019 → …
Project: Research
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Effortless Listening using Brain Feedback
Østergaard, J., Andersen, O. K., Arguissain, F., Baboukani, P. S. & Mohammadi, Y.
01/09/2019 → …
Project: Research
Research output
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A biomarkers assessments 5 years after total knee replacement in osteoarthritis patients with and without chronic postoperative pain
Giordano, R., Capriotti, C., Gerra, M. C., Dallabona, C., Arendt-Nielsen, L. & Petersen, K. K-S., Sept 2023.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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ACE1 rs1799752 Polymorphism is not Associated with Long-COVID Symptomatology in Previously Hospitalized COVID-19 Survivors
Fernández-de-Las-Peñas, C., Arendt-Nielsen, L., Díaz-Gil, G., Gil-Crujera, A., Gómez-Sánchez, S. M., Ambite-Quesada, S., Palomar-Gallego, M. A., Pellicer-Valero, O. J. & Giordano, R., Mar 2023, In: Journal of Infection. 86, 3, p. e67-e69Research output: Contribution to journal › Letter › peer-review
Open Access2 Citations (Scopus) -
Acute pain drives different effects on local and global cortical excitability in motor and prefrontal areas: insights into interregional and interpersonal differences in pain processing
De Martino, E., Casali, A., Casarotto, S., Hassan, G., Rosanova, M., Graven-Nielsen, T. & Ciampi de Andrade, D., 15 Sept 2023, In: Cerebral Cortex. 33, 18, p. 9986-9996 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Datasets
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Diagnostic Accuracy of Perception Threshold Tracking in the Detection of Small Fiber Damage in Type 1 Diabetes
Røikjer, J. (Creator), Croosu , S. S. (Creator), Sejergaard, B. F. (Creator), Hansen, T. M. S. (Creator), Frøkjær, J. B. (Creator), Søndergaard, C. B. (Creator), Petropoulos, I. N. (Creator), Malik, R. A. (Creator), Nielsen, E. (Creator), Mørch, C. D. (Creator) & Ejskjær, N. (Creator), Sage Journals, 2023
DOI: 10.25384/sage.c.6445639, https://sage.figshare.com/collections/Diagnostic_Accuracy_of_Perception_Threshold_Tracking_in_the_Detection_of_Small_Fiber_Damage_in_Type_1_Diabetes/6445639
Dataset
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Diagnostic Accuracy of Perception Threshold Tracking in the Detection of Small Fiber Damage in Type 1 Diabetes
Røikjer, J. (Creator), Croosu , S. S. (Creator), Sejergaard, B. F. (Creator), Hansen, T. M. S. (Creator), Frøkjær, J. B. (Creator), Søndergaard, C. B. (Creator), Petropoulos, I. N. (Creator), Malik, R. A. (Creator), Nielsen, E. (Creator), Mørch, C. D. (Creator) & Ejskjær, N. (Creator), Sage Journals, 2023
DOI: 10.25384/sage.c.6445639.v1, https://sage.figshare.com/collections/Diagnostic_Accuracy_of_Perception_Threshold_Tracking_in_the_Detection_of_Small_Fiber_Damage_in_Type_1_Diabetes/6445639/1
Dataset
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Supplementary Material for: Serological Biomarkers at Hospital Admission Are Not Related to Long-Term Post-COVID Fatigue and Dyspnea in COVID-19 Survivors
Fernández-De-Las-Penãs, C. (Creator), Ryan-Murua, P. (Creator), Rodríguez-Jiménez, J. (Creator), Palacios-Cenã, M. (Creator), Arendt-Nielsen, L. (Creator) & Torres-Macho, J. (Creator), Karger Publishers, 5 Apr 2022
DOI: 10.6084/m9.figshare.19518862.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Serological_Biomarkers_at_Hospital_Admission_Are_Not_Related_to_Long-Term_Post-COVID_Fatigue_and_Dyspnea_in_COVID-19_Survivors/19518862/1
Dataset: Supplementary material
Prizes
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3rd Best Paper Award
Rettore Andreis, Felipe (Recipient), Jensen, Winnie (Recipient), Janjua, Taha (Recipient), Meijs, Suzan (Recipient) & Nielsen, Thomas Gomes Nørgaard dos Santos (Recipient), Oct 2023
Prize: Conference prizes
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The Svend Andersen Talent Prize 2022
Petersen, Kristian Kjær-Staal (Recipient), 2022
Prize: Honorary prizes and appointments
Activities
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PhD Defense Pernille Døssing Kwateng Diasso (Event)
Daniel Ciampi de Andrade (Member)
21 Apr 2023Activity: Memberships › Membership of review committee
File -
Neuroscience Academy Denmark (NAD) (External organisation)
Carsten Dahl Mørch (Member (Appointed by AAU))
2022 → …Activity: Memberships › Membership of committees, commissions, boards, councils, associations, organisations, or similar
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Girls' Day in Science AAU 2021
Rikke Hagensby Jensen (Organizer), Anna Lyhne Jensen (Organizer), Alisa Ananjeva (Participant), Ann-Louise Andersen (Participant), Maria Støttrup Schiønning Larsen (Participant), Anne Marie Svane (Participant), Amelia Reimer Borregaard (Participant), Katrine Vogt Møller (Participant), Kamilla Heimar Andersen (Participant), Ásgerdur Arna Pálsdóttir (Participant), Sara Nielsen (Participant), Aleksandra Kaszowska (Participant), Emilie Maria Nybo Arendttorp (Participant), Suzan Meijs (Participant), Shima Gholinezhadasnefestani (Participant), Leonora Charlotte Malabi Eberhardt (Participant), Turid Borgestrand Øien (Participant), Lene Tolstrup Sørensen (Participant), Charlotte Overgaard Wilhelmsen (Participant) & Samba Eveline Kabemba Kaniki (Participant)
6 Oct 2021Activity: Attending an event › Organisation or participation in workshops, courses, seminars, exhibitions or similar
Press/Media
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Kunstnerisk event i Vrå sætter fokus på smerter
08/11/2023
1 item of Media coverage
Press/Media: Press / Media
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Smerteselskab vælger første indikationer - jagter kapital
30/10/2023
2 items of Media coverage
Press/Media: Press / Media
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Hvad gør mest ondt: En fødsel eller et hårdt spark i skridtet?
05/10/2023
1 item of Media coverage
Press/Media: Press / Media