Projects per year
Organization profile
Research centre name:
Centre for Neuroplasticity and Pain
Date of establishment and expected operational period of the centre:
2015-2025
Initials of research centre:
CNAP
Head of research centre:
Prof. Thomas Graven-Nielsen
Participants and partners?
CNAP consists of researchers from four different research groups at AAU:
- Neural Engineering and Neurophysiology
- Integrative Neuroscience
- Pain and Motor System Plasticity
- Translational Pain Biomarkers
Who are we?
Center for Neuroplasticity and Pain (CNAP) is a Center of Excellence at the Department of Health Science and Technology, funded by the Danish National Research Foundation in the period 2015-2025.
What are our fundamental goals/objectives?
The ambition of CNAP is to identify and modulate key features of human pain neuroplasticity. We keenly believe that this can be achieved through a systematic engineering approach, including provoking, probing and modulation of the dynamic neuroplastic properties of the pain system.
Our research – what we do?
CNAP applies a basic research approach where new advanced biomedical provocation and probing platforms are being discovered and applied to study novel aspects of the human pain neuroplasticity. When an injury results in acute pain, the nervous system undergoes an adaptive neuroplastic response resulting in an increase in sensitivity. After some time, the pain neuroplasticity is normalized as the injury heals. In some cases, such neuroplastic processes fail to normalize during convalescence, and acute pain develops into chronic pain with hypersensitivity. The continuing pain after injury resolution may be caused by maladaptive pain neuroplasticity. In contrast, advantageous neuroplasticity permits the nervous system to cope with challenges such as maladaptive pain neuroplasticity to help returning to a pain-free state.
Interdisciplinary, international cooperation, and research training combined with the capacity of leading researchers is the core research philosophy of CNAP. Thus, all our research groups are highly interdisciplinary and include experts within e.g. biomedical engineering, neuropsychology, pharmacology, biophysics, and medicine. To secure international excellence, CNAP strives for an equal distribution between genders and between national and international staff.
How does our research contribute to societal health challenges?
Chronic pain is a key societal challenge: it affects one out of five adults, and is generally poorly treated. Through the research we conduct at CNAP, we contribute to improving pain treatments.
How are we funded?
CNAP is funded by the Danish National Research Foundation (DNRF121) and by the European Union’s Horizon 2020 research and innovation programme (Marie Skłodowska-Curie grant agreement No 754465).
Who are our key collaborators?
CNAP cooperates with several renowned national and international researchers. In addition, a number of international collaborators are embedded within CNAP and participate actively in the centre’s activities.
Network
Profiles
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Lars Arendt-Nielsen
- The Faculty of Medicine - Professor
- Department of Health Science and Technology - Professor
- Center for Sensory-Motor Interaction
- Translational Biomarkers in Pain and Precision Medicine
- Center for Neuroplasticity and Pain
- Aalborg University Hospital
- Klinik Medicin og Akut
- Department of Gastroenterology and Hepatology - Professor
Person: Associated to Aalborg UH, VIP
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Shellie Boudreau
- The Faculty of Medicine - Associate Professor
- Department of Health Science and Technology - Associate Professor
- Center for Sensory-Motor Interaction
- Pain and Motor System Plasticity
- Center for Neuroplasticity and Pain
Person: VIP
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C19 Symptom Mapping
Boudreau, S., Bøggild, H., Duroux, M. & Holden, S.
26/03/2020 → …
Project: Research
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Investigation of temporal and spatial integration of pain information in the nociceptive system
01/11/2019 → …
Project: Research
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Effortless Listening using Brain Feedback
Østergaard, J., Andersen, O. K., Arguissain, F., Baboukani, P. S. & Mohammadi, Y.
01/09/2019 → …
Project: Research
Research output
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Acute postoperative pain after orthognathic surgery can be predicted by the preoperative evaluation of conditioned pain modulation and pain catastrophizing
Takashima, K., Oono, Y., Takagi, S., Wang, K., Arendt-Nielsen, L. & Kohase, H., 5 Mar 2022, In: Pain Reports. 7, 2, p. E989 10 p., e989.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Downloads (Pure) -
Alterations of tibialis anterior muscle activation pattern in subjects with type 2 diabetes and diabetic peripheral neuropathy
Favretto, M. A., Cossul, S., Andreis, F. R., Nakamura, L. R., Ronsoni, M. F., Tesfaye, S., Selvarajah, D. & Marques, J. L. B., Mar 2022, In: Biomedical Physics & Engineering Express. 8, 2, 025001.Research output: Contribution to journal › Journal article › Research › peer-review
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Analgesic and antipruritic effect of salicornia extract-infused cream on healthy participants
Giordano, R., Aliotta, G. E., Lo Vecchio, S., Fredsgaard, M., Arendt-Nielsen, L., Thomsen, M. H. & Stensballe, A., 2022.Research output: Contribution to conference without publisher/journal › Poster › Research › peer-review
Datasets
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Accuracy of the Upper Limb Prediction Algorithm PREP2 Applied 2 Weeks Poststroke: A Prospective Longitudinal Study
Nielsen, J. F. (Creator), Arguissain, F. G. (Creator), Brunner, I. C. (Creator) & Lundquist, C. B. (Creator), Sage Journals, 1 Jan 2020
DOI: 10.25384/sage.c.5215078.v1, https://doi.org/10.25384%2Fsage.c.5215078.v1
Dataset
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Intensive, personalized multimodal rehabilitation in patients with primary or revision total knee arthroplasty: a retrospective cohort study
Larsen, J. B. (Creator), Madeleine, P. M. (Creator), Arendt-Nielsen, L. (Creator) & Mogensen, L. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.4813893.v1, https://doi.org/10.6084%2Fm9.figshare.c.4813893.v1
Dataset
Prizes
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Best Abstract Prize
Petersen, Kristian Kjær-Staal (Recipient) & Larsen, Dennis Boye (Recipient), 7 Sep 2019
Prize: Conference prizes
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Activities
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Girls' Day in Science AAU 2021
Rikke Hagensby Jensen (Organizer), Anna Lyhne Jensen (Organizer), Alisa Ananjeva (Participant), Ann-Louise Andersen (Participant), Maria Støttrup Schiønning Larsen (Participant), Anne Marie Svane (Participant), Amelia Reimer Borregaard (Participant), Katrine Vogt Møller (Participant), Kamilla Heimar Andersen (Participant), Ásgerdur Arna Pálsdóttir (Participant), Sara Nielsen (Participant), Aleksandra Kaszowska (Participant), Emilie Maria Nybo Arendttorp (Participant), Suzan Meijs (Participant), Shima Gholinezhadasnefestani (Participant), Leonora Charlotte Malabi Eberhardt (Participant), Turid Borgestrand Øien (Participant), Lene Tolstrup Sørensen (Participant), Charlotte Overgaard Wilhelmsen (Participant) & Samba Eveline Kabemba Kaniki (Participant)
6 Oct 2021Activity: Attending an event › Organisation or participation in workshops, courses, or seminars
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Science communications - the advantages and pitfalls of preprints
Kathrine Bjerg Bennike (Lecturer) & Anne Lyhne Høj (Lecturer)
23 Sep 2021Activity: Talks and presentations › Talks and presentations in private or public companies
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Scientific Reports (Journal)
Kristian Kjær Petersen (Peer reviewer)
2021 → …Activity: Editorial work and peer review › Peer review of manuscripts › Research
Press / Media
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Mere end en million lid er af kroniske smerter
18/06/2022
1 item of Media coverage
Press/Media: Press / Media
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Fra isfabrik til innovativ fiskefarm
Mette Hedegaard Thomsen, Charlotte Fonseca Holmene, Allan Stensballe, Marco Maschietti, Malthe Fredsgaard, Rocco Giordano, Tanmay Chaturvedi, Laura Sini Sofia Hulkko & Julaine Tania Enas
02/06/2022
2 items of Media coverage
Press/Media: Press / Media
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Hvorfor har hver femte stadig ondt efter at have fået en knæprotese?
17/05/2022
1 item of Media coverage
Press/Media: Press / Media