Organisation profile

Head of research group:

Mette Nyegaard

Who we are?

Members of the group are genome researchers, computational and molecular biologists with expertise in human genetics and genomics, biobanking, genome-wide association studies, sequencing, transcriptomics, polygenic risk scores, risk prediction and biomarkers.

Our research – what we do?

Use genetics to systematically understand the biological basis of common complex diseases and identify biological subtypes of disease. We have focus on women's reproductive health, in particular endometriosis, cardiometabolic diseases and brain disorders. We work in the interface between wet-lab and big data analysis. Our goal is to turn genetic findings into personalised medicine and benefits patients.

How does our research contribute to societal health challenges?

Despite a high prevalence and socio-economic burden, women’s reproductive disorders remain underfunded and consequently under-researched. Many disorders, such as endometriosis and repeated pregnancy loss affects women during the prime years of their lives, causing problems for the women and their families as well as loss of productivity for the society. By developing molecular predictors and decision support tools within women's health our research contributes to increased equity in health and society.

Who are our key collaborators?

National and International research institutions

• Aarhus University
• Aarhus University Hospital
• Copenhagen University
• Technical University of Denmark
• Hvidovre Hospital
• University of Southern Denmark
• University of San Francisco, Oxford Big Data Institute
• University of Calgary
• University College London
• Oxford University.

Consortia and cohorts

• Danish Blood Donor Genomic Consortium (co-PI)
• Copenhagen Hospital Biobank (CHB)
• UK Biobank
• Biobank Rare Variant Analysis (BRaVa) consortium (Danish co-PI)
• Nordic Consortium of Womens Reproductive Health (NCWRH) (co-chair)
• International Endometriosis Genome Consortium (IEGC) (Danish PI)
• The Dan-NICAD (Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease) group

Industry

• PrecisionLife
• deCODE genetics
• Novo Nordisk