Head of research group: Torben Moos

Our research:

We focus on understanding the biology of the brain’s vasculature both in health and pathology. We also focus on the restraints of the brain’s vasculature for drug delivery. We develop strategies for the delivery of drugs to the brain using, e.g., gene therapy, therapeutic nanoparticles, and antibodies intended for the treatment of patients with brain diseases, such as Alzheimer’s disease or genetic diseases like Niemann-Pick disease. Our experimental models are primarily based on rodent in vivo models and in vitro primary cell culture models.

How our research contributes to societal health challenges:

We contribute with basic knowledge about the anatomy and physiology of the brain vasculature, which is helpful in increasing the knowledge about the development and progression of brain diseases like dementia, Alzheimer’s disease, and hemorrhage. We also contribute to optimizing existing treatment and developing new treatment strategies for multiple types of brain diseases.

Key collaborators:

We collaborate with leading scientists from the University of Copenhagen, Aarhus University, University of Southern Denmark, The Technical University of Denmark (DTU), Uppsala University, University of Hamburg, and other research groups at Aalborg University. Furthermore, we collaborate with leading national and international pharmaceutical companies.