Projects per year
Organisation profile
Organisation profile
Head of research group: Vladimir Zachar
Who we are?
The main theme of our research is investigation of stem cells, replacement tissues, and probiotics in order to harness their regenerative potential and synergies with the ultimate goal of developing novel therapeutic approaches.
Our research – what we do?
Our research focuses on the development of innovative interdisciplinary approaches to control the fate of stem cells and devise original clinically applicable cell- and tissue-based products. Major efforts are currently directed towards these areas:
-
Use of adipose-derived stem cells in the treatment of chronic wounds, and bone and cartilage reconstruction
-
Cell-based treatment of limbal stem cell deficiency
-
Engineering of muscle tissue
-
Probiotic Research Initiative: Application of probiotics in disease management and tissue regeneration
How does our research contribute to societal health challenges?
The group is involved in the translational research into novel regenerative therapies based on the use of probiotics, stem cells, and tissue engineering.
Who are our key collaborators?
-
Prof. Hjortdal, Eye clinic, Aarhus University
-
Prof. Kastrup, The heart center, Copenhagen University
-
Prof. Ingersle v, Prof. Kesmodel, Fertility clinic and center for preimplantation diagnostic, Aalborg University Hospital
-
Prof. Starch-Jensen, Dpt. of maxillary surgery, Aalborg University Hospital
-
Assoc. Prof. Rasmussen, Dpt. of orthopedic surgery, Aalborg University Hospital
-
Ass. Prof. Dolatshahi-Pirouz, DTU, Copenhagen
-
Deerland Probiotics & Enzymes
-
Innosurge
Fingerprint
Collaborations from the last five years
Profiles
-
Sara Aghazadeh
- The Faculty of Medicine - PhD Student, Research assistant
- Department of Health Science and Technology - PhD Student, Research assistant
- Regenerative Medicine - Research assistant
Person: VIP, External
-
Hiva Alipour
- The Faculty of Medicine - Associate Professor
- Department of Health Science and Technology - Associate Professor
- Regenerative Medicine
- Probiotic Research Initiative™
Person: VIP
-
Fereshteh Dardmeh
- The Faculty of Medicine - Associate Professor
- Department of Health Science and Technology - Associate Professor
- Regenerative Medicine
- Probiotic Research Initiative™
Person: VIP
-
PROMEAT: A truly scalable next-generation cultured meat with bioprotectives and health benefits
Pennisi, P., Xuan, Z. & Zandi, N.
01/09/2021 → 29/02/2024
Project: Research
-
The Role of pigmentation and SERPINF1gene expression in Limbal Epithelial Stem cells’ self-renewal capability
Aghazadeh, S., Alipour, H. & Zachar, V.
01/06/2020 → 31/05/2024
Project: PhD Project
Research output
-
ChatGPT in medicine: A novel case of Dr Jekyll and Mr Hyde
Astorp, M. S., Emmersen, J. & Andersen, S., Aug 2023, In: Ethics, Medicine and Public Health. 29, 100923.Research output: Contribution to journal › Comment/debate › Research › peer-review
1 Citation (Scopus) -
Correction: Peng et al. Distinct Dominant Lineage from In Vitro Expanded Adipose-Derived Stem Cells (ASCs) Exhibits Enhanced Wound Healing Properties. Cells 2022, 11, 1236
Peng, Q., Ren, G., Xuan, Z., Duda, M., Pennisi, C. P., Porsborg, S. R., Fink, T. & Zachar, V., 6 Apr 2023, In: Cells. 12, 7, 1095.Research output: Contribution to journal › Comment/debate › Research › peer-review
Open Access -
Exploring the Potential of Ultrasound Therapy to Reduce Skin Scars: An In Vitro Study Using a Multi-Well Device Based on Printable Piezoelectric Transducers
Riis Porsborg, S., Krzyslak, H., Pierchala, M. K., Trolé, V., Astafiev, K., Lou-Moeller, R. & Pennisi, C. P., 9 May 2023, In: Bioengineering (Basel, Switzerland). 10, 5, 566.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Downloads (Pure)
Datasets
-
Data for research article titled: "Lactobacillus rhamnosus PB01 (DSM 14870) supplementation affects markers of sperm kinematic parameters in a diet-induced obesity mice model"
Dardmeh, F. (Creator), Alipour, H. (Contributor), Gazerani, P. (Creator), Van Der Horst, G. (Contributor), Brandsborg, E. (Creator) & Nielsen, H. I. (Creator), Figshare, 27 Sept 2017
DOI: 10.6084/m9.figshare.5446525.v1, https://figshare.com/articles/dataset/Data_for_research_article_titled_Lactobacillus_rhamnosus_PB01_DSM_14870_supplementation_affects_markers_of_sperm_kinematic_parameters_in_a_diet-induced_obesity_mice_model_/5446525/1
Dataset
-
Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Creator), Nielsen, F. M. (Creator), Porsborg, S. R. (Creator), Emmersen, J. (Creator), Fink, T. (Creator), Hjortdal, J. Ø. (Creator), Bath, C. (Creator) & Zachar, V. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822
Dataset
-
Maintaining RNA Integrity for Transcriptomic Profiling of Ex Vivo Cultured Limbal Epithelial Stem Cells after Fluorescence-Activated Cell Sorting (FACS)
Liu, L. (Creator), Nielsen, F. M. (Creator), Porsborg, S. R. (Creator), Emmersen, J. (Creator), Fink, T. (Creator), Hjortdal, J. Ø. (Creator), Bath, C. (Creator) & Zachar, V. (Creator), Figshare, 2017
DOI: 10.6084/m9.figshare.c.3952822.v1, https://figshare.com/collections/Maintaining_RNA_Integrity_for_Transcriptomic_Profiling_of_Ex_Vivo_Cultured_Limbal_Epithelial_Stem_Cells_after_Fluorescence-Activated_Cell_Sorting_FACS_/3952822/1
Dataset
Activities
-
BMC Biomedical Engineering (Journal)
Pablo Pennisi (Editor)
Jul 2023 → …Activity: Editorial work and peer review › Journal editor › Research
-
Tailoring mechanical signals to control muscle cell differentiation
Pablo Pennisi (Lecturer)
30 Jun 2023Activity: Talks and presentations › Conference presentations
-
CleanMeat - Future Sustainable Meat Protein
Pablo Pennisi (Opponent)
31 May 2023Activity: Examination › External examination
Press/Media
-
Debat: Kampen om lægestuderendes læring
Lars Stig Andersen, Jeppe Emmersen & Jette Kolding Kristensen
03/04/2023
1 Media contribution
Press/Media: Press / Media
-
Danske forskere vil 3D-printe kunstigt væv med levende celler
25/06/2022
1 item of Media coverage
Press/Media: Press / Media
-
Lactobio er på jagt efter naturens superbakterier
28/04/2022
2 items of Media coverage
Press/Media: Press / Media