• Phone2216 0497, +45 9940 9832, +45 9815 4008, 9940 9832, 9815 4008, +45 2216 0497
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  • Fredrik Bajers Vej 7, A2-219

    9220 Aalborg Ø

    Denmark

  • Fredrik Bajers Vej 7

    9220 Aalborg Ø

    Denmark

19942019
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Research Output 1994 2019

2019
Prospective Studies
Pain
Sports
Torque
Hip

Alterations in temporal summation of pain and conditioned pain modulation across an episode of experimental exercise-induced low back pain

McPhee, M. & Graven-Nielsen, T., Mar 2019, In : Journal of Pain. 20, 3, p. 264-276 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Low Back Pain
Pain
Pain Threshold
Pressure
Catastrophization
Healthy Volunteers
Pain
Pain Threshold
Leg
Conditioning (Psychology)

Correlations between the active straight leg raise, sleep and somatosensory sensitivity during pregnancy with post-partum lumbopelvic pain: an initial exploration

Beales, D. J., Gaynor, O., Harris, J., Fary, R., O'Sullivan, P. B., Slater, H., Graven-Nielsen, T. & Palsson, T. S., 1 Jan 2019, In : Scandinavian Journal of Pain. 19, 1, p. 53-60 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Leg
Sleep
Pain
Pregnancy
Quality of Life
18 Downloads (Pure)

Cortical Connectivity in Chronic Widespread Pain

Van Ettinger-Veenstra, H., Lundberg, P., Alföldi, P., Södermark, M., Graven-Nielsen, T., Sjörs, A., Engström, M. & Gerdle, B., 2019, (Accepted/In press) In : Journal of Pain Research.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
1 Downloads (Pure)

Do sensorimotor cortex activity, an individual's capacity for neuroplasticity, and psychological features during an episode of acute low back pain predict outcome at 6 months: a protocol for an Australian, multisite prospective, longitudinal cohort study

Jenkins, L. C., Chang, W-J., Buscemi, V., Liston, M., Toson, B., Nicholas, M., Graven-Nielsen, T., Ridding, M., Hodges, P. W., McAuley, J. H. & Schabrun, S. M., 22 May 2019, In : BMJ Open. 9, 5, 8 p., e029027.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neuronal Plasticity
Low Back Pain
Longitudinal Studies
Cohort Studies
Psychology
100 Downloads (Pure)

Effect of sustained experimental muscle pain on joint position sense

Summers, S. J., Schabrun, S. M., Hirata, R. P., Graven-Nielsen, T., Cavaleri, R. & Chipchase, L. S., Apr 2019, In : Pain Reports. 8 p., e737.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Enhanced pro-nociceptive mechanisms are present in recurrent low back pain patients, but only during a painful episode, in contrast to anti-nociceptive mechanisms

McPhee, M. E. & Graven-Nielsen, T., 2019, (Accepted/In press).

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Intramuscular Injections
Nerve Growth Factor
Hypersensitivity
Pressure
Pain
10 Downloads (Pure)

Exercise-induced hypoalgesia after isometric wall squat exercise: A test-retest reliabilty study

Vaegter, H. B., Lyng, K. D., Yttereng, F. W., Christensen, M. H., Sørensen, M. B. & Graven-Nielsen, T., 1 Jan 2019, In : Pain Medicine. 20, 1, p. 129-137 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Exercise Test
Exercise
Pain Threshold
Pressure
Reproducibility of Results

Exercise induced hypoalgesia in pain-free and chronic pain populations: State of the art and future directions

Rice, D., Nijs, J., Kosek, E., Wideman, T., Hasenbring, M. I., Koltyn, K., Graven-Nielsen, T. & Polli, A., 20 Mar 2019, In : Journal of Pain.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Pain
Pain
Population
Exercise
Direction compound

Experimental cervical interspinous ligament pain altered cervical joint motion during dynamic extension movement

Qu, N., Lindstrøm, R., Graven-Nielsen, T. & Hirata, R. P., 1 May 2019, In : Clinical Biomechanics. 65, p. 65-72 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Neck Pain
Ligaments
Joints
Zygapophyseal Joint
Pressure

High frequency repetitive transcranial magnetic stimulation to the left dorsolateral prefrontal cortex modulates sensorimotor cortex function in the transition to sustained muscle pain

De Martino, E., Seminowicz, D. A., Schabrun, S. M., Petrini, L. & Graven-Nielsen, T., 1 Feb 2019, In : NeuroImage. 186, p. 93-102 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Transcranial Magnetic Stimulation
Myalgia
Prefrontal Cortex
Pain Threshold
Somatosensory Evoked Potentials

Hypoalgesia after bicycling at lactate threshold is reliable between sessions

Vaegter, H. B., Bjerregaard, L. K., Redin, M-M., Rasmussen, S. H. & Graven-Nielsen, T., 30 Jan 2019, In : European Journal of Applied Physiology. 119, 1, p. 91-102 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Bicycling
Lactic Acid
Exercise
Pain Threshold
Superficial Back Muscles

Increased muscle pain evoked by ischemic contractions in a nerve growth factor (NGF)-sensitized muscle

Sørensen, L. B., Gazerani, P. & Graven-Nielsen, T., 2019, (Accepted/In press).

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Increased postural stiffness during challenging postural tasks in patients with knee osteoarthritis with high pain sensitization

Hirata, R. P., Skou, S. T., Simonsen, O., Rasmussen, S., Laursen, M. B. & Graven-Nielsen, T., 1 Jan 2019, In : Clinical Biomechanics. 61, p. 129-135 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Knee Osteoarthritis
Pressure
Pain
Pain Threshold
Knee Injuries

Local hypoalgesia to pressure and enhanced sequential conditioned pain modulation following fatiguing trunk extensor exercise

McPhee, M. E. & Graven-Nielsen, T., 2019.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Motor adaptation varies between individuals in the transition to sustained pain

Summers, S. J., Chipchase, L. S., Hirata, R., Graven-Nielsen, T., Cavaleri, R. & Schabrun, S. M., 8 May 2019, In : Pain.

Research output: Contribution to journalJournal articleResearchpeer-review

Myalgia
Pain
Biomechanical Phenomena
Musculoskeletal Pain
Pronation
2 Citations (Scopus)

Origin of neck pain and direction of movement influence dynamic cervical joint motion and pressure pain sensitivity

Qu, N., Lindstrøm, R., Hirata, R. P. & Graven-Nielsen, T., Jan 2019, In : Clinical Biomechanics. 61, p. 120-128 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Neck Pain
Joints
Pressure
Pain
Myalgia

Pain-Induced Reduction in Corticomotor Excitability is Counteracted by Combined Action-Observation and Motor Imagery

Larsen, D. B., Graven-Nielsen, T. & Boudreau, S., 2 May 2019, (Accepted/In press) In : Journal of Pain. 30 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Sessions of prolonged continuous theta burst stimulation or high-frequency 10 Hz stimulation to left dorsolateral prefrontal cortex for three days decreased pain sensitivity by modulation of the efficacy of conditioned pain modulation

De Martino, E., Fernandes, A. M., Galhardoni, R., De Oliveira Souza, C., Ciampi De Andrade, D. & Graven-Nielsen, T., 24 May 2019, In : Journal of Pain.

Research output: Contribution to journalJournal articleResearchpeer-review

Transcranial Magnetic Stimulation
Prefrontal Cortex
Pain
Pain Threshold
Hot Temperature

Smerter i bevægeapparatet 1: Muskelsmerte

Bliddal, H. & Graven-Nielsen, T., 2019, Smerter: Baggrund, Evidens og Behandling. U. Werner, M., Finnerup, N. B. & Arendt-Nielsen, L. (eds.). 4. ed. FADL's Forlag, p. 378-390

Research output: Contribution to book/anthology/report/conference proceedingBook chapterResearchpeer-review

Temporal summation of pain and pain catastrophizing is associated with self-reported pain after 12 weeks: A prospective cohort study of patients with low back pain in general practice

Petersen, K. K., Jensen, M. B., Graven-Nielsen, T., Hauerslev, L. V., Arendt-Nielsen, L. & Rathleff, M. S., 2019, (Accepted/In press).

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

The Effect of Stress on Repeated Painful Stimuli With And Without Painful Conditioning

Høgh, M. S., Nørgaard Poulsen, J., Petrini, L. & Graven-Nielsen, T., 2019, (Accepted/In press) In : Pain Medicine.

Research output: Contribution to journalJournal articleResearchpeer-review

The effects of use-dependent neuroplasticity and chronic pain on somatosensory peripheral and cortical excitability

Andreas, A. M. Z., Arguissain, F., Kleber, B., Vuust, P., Boudreau, S., Flor, H. & Graven-Nielsen, T., 2019, (Accepted/In press).

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

2018

Acid-induced experimental knee pain and hyperalgesia in healthy humans

Asaki, T., Wang, K., Luo, Y., Arendt-Nielsen, T., Graven-Nielsen, T. & Arendt-Nielsen, L., Feb 2018, In : Experimental Brain Research. 236, 2, p. 587-598 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Hyperalgesia
Knee
Pain
Acids
Adipose Tissue
2 Citations (Scopus)
11 Downloads (Pure)

Acute Procedural Pain in Children: Intervention with the Hospital Clown

Kristensen, H. N., Lundbye-Christensen, S., Haslund-Thomsen, H., Graven-Nielsen, T. & Elgaard Sørensen, E., Nov 2018, In : The Clinical Journal of Pain. 34, 11, p. 1032–1038 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Acute Pain
Pain
Phlebotomy
Age Groups
Control Groups
139 Downloads (Pure)
Open Access
File
Myalgia
Exercise
Leg
Pain Threshold
Arteries

Bradykinin-2 receptor antagonist, HOE 140, prevents the development of delayed onset muscle soreness in female and male rats

Poulsen, J. N., Graven-Nielsen, T. & Gazerani, P., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access
5 Citations (Scopus)
96 Downloads (Pure)

Cervical flexion and extension includes anti-directional cervical joint motion in healthy adults

Wang, X., Lindstroem, R., Plocharski, M., Østergaard, L. R. & Graven-Nielsen, T., 2018, In : Spine Journal. 18, 1, p. 147-154

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Joints
Articular Range of Motion
Healthy Volunteers
Fluoroscopy
Observational Studies

Chronic postoperative pain after total knee arthroplasty is associated with a functional MRI signature of facilitated temporal summation of pain

Kurien, T., Iwabuchi, S., Petersen, K. K., Reckziegel, D., Cottam, W., Kerslake, R., Edwards, K., Graven-Nielsen, T. & Arendt-Nielsen, L., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access

Conditioning pain modulation reduces the initial part of temporal pain summation in healthy males

Holden, S., Petersen, K. K. & Graven-Nielsen, T., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access
1 Citation (Scopus)

Cortical somatosensory excitability is modulated in response to several days of muscle soreness

Martino, E. D., Petrini, L., Schabrun, S. & Graven-Nielsen, T., Nov 2018, In : Journal of Pain. 19, 11, p. 1296-1307 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Pain Threshold
Myalgia
Wrist
Motor Evoked Potentials
Somatosensory Evoked Potentials

Corticomotor excitability reduction in response to acute experimental muscle pain is not modulated by engagement in a two-back task

Larsen, D. B., Graven-Nielsen, T., Hirata, R. P., Schabrun, S., Seminowicz, D. & Boudreau, S., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access
1 Citation (Scopus)
66 Downloads (Pure)

Differential corticomotor excitability responses to hypertonic saline-induced muscle pain in forearm and hand muscles

Larsen, D. B., Graven-Nielsen, T., Hirata, R. P. & Boudreau, S. A., 2018, In : Neural Plasticity. 2018, 9 p., 7589601.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Myalgia
Forearm
Hand
Motor Evoked Potentials
Muscles
5 Citations (Scopus)

Disruption of cortical synaptic homeostasis in individuals with chronic low back pain

Thapa, T., Graven-Nielsen, T., Chipchase, L. S. & Schabrun, S. M., May 2018, In : Clinical Neurophysiology. 129, 5, p. 1090-1096 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Low Back Pain
Homeostasis
Motor Evoked Potentials
Neuronal Plasticity
Musculoskeletal Pain
40 Downloads (Pure)

Distinct patterns of variation in the distribution of knee pain

Boudreau, S. A., Royo, A. C., Matthews, M., Graven-Nielsen, T., Kamavuako, E. N., Slabaugh, G., Thorborg, K., Vicenzino, B. & Rathleff, M. S., 8 Nov 2018, In : Scientific Reports. 8, 1, p. 1-12 12 p., 16522.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Knee
Pain
Patella
Principal Component Analysis
Cluster Analysis

Effect of sustained experimental pain on joint position sense

Summers, S., Schabrun, S., Hirata, R. P., Graven-Nielsen, T., Cavaleri, R. & Chipchase, L., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access

Effects of repeated conditioning pain modulation in healthy volunteers

Høgh, M., Petersen, K. K. & Graven-Nielsen, T., 2018, In : European Journal of Pain. 22, 10, p. 1833-1843 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Healthy Volunteers
Pain Threshold
Pain
Pain Measurement
Leg

Exercise-induced muscle soreness in a pre-sensitized muscle: a novel model to provoke central and peripheral neuroplastic effects

De Martino, E., Zandalasini, M., Schabrun, S., Petrini, L. & Graven-Nielsen, T., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access
19 Downloads (Pure)

Experimental low back pain decreased trunk muscle activity in currently asymptomatic recurrent low back pain patients during step tasks

Larsen, L. H., Hirata, R. P. & Graven-Nielsen, T., 2018, In : Journal of Pain. 19, 5, p. 542-551

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Low Back Pain
Muscles
Pain
Back Muscles
Acute Pain
2 Citations (Scopus)

Experimental muscle hyperalgesia modulates sensorimotor cortical excitability, which is partially altered by unaccustomed exercise

De Martino, E., Zandalasini, M., Schabrun, S., Petrini, L. & Graven-Nielsen, T., Dec 2018, In : Pain. 159, 12, p. 2493-2502 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Myalgia
Hyperalgesia
Nerve Growth Factor
Exercise
Muscles
1 Citation (Scopus)

Experimental referred pain extends toward previously injured location: An explorative study

Palsson, T. S., Boudreau, S. A., Krebs, H. J. & Graven-Nielsen, T., 1 Oct 2018, In : Journal of Pain. 19, 10, p. 1189-1200 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Referred Pain
Pain
Pain Threshold
Pressure
Leg

Hypoalgesia after bicycling at lactate threshold is reliable between sessions in pain-free subjects

Vaegter, H., Redin, M., Rasmussen, S., Bjerregaard, L. K. & Graven-Nielsen, T., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access
1 Citation (Scopus)
111 Downloads (Pure)

Increased pain sensitivity in accident-related chronic pain patients with comorbid posttraumatic stress

Vaegter, H. B., Andersen, T. E., Harvold, M., Andersen, P. G. & Graven-Nielsen, T., 2018, In : The Clinical Journal of Pain. 34, 4, p. 313-321

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Chronic Pain
Accidents
Post-Traumatic Stress Disorders
Pain
Pain Threshold
1 Citation (Scopus)
1 Downloads (Pure)

Kinesiophobia is associated with pain intensity but not pain sensitivity before and after exercise: an explorative analysis

Vaegter, H. B., Madsen, A. B., Handberg, G. & Graven-Nielsen, T., 2018, In : Physiotherapy. 104, 2, p. 187-193

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

Left DLPFC rTMS counteracts the sensorimotor cortical excitability changes in the transition to sustained muscle pain

De Martino, E., Seminowicz, D., Schabrun, S., Petrini, L. & Graven-Nielsen, T., 2018.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearchpeer-review

Open Access
1 Citation (Scopus)

Left dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation reduces the development of long-term muscle pain

Seminowicz, D. A., de Martino, E., Schabrun, S. M. & Graven-Nielsen, T., 1 Dec 2018, In : Pain. 159, 12, p. 2486-2492 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Transcranial Magnetic Stimulation
Myalgia
Prefrontal Cortex
Catastrophization
Pain
41 Downloads (Pure)

Light touch contact improves pain-evoked postural instability during quiet standing

Hirata, R. P., Christensen, S. W., Agger, S., Svindt, M., Røssner, N., Abildgaard, J., Vuillerme, N. & Graven-Nielsen, T., 1 Dec 2018, In : Pain Medicine. 19, 12, p. 2487-2495 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Touch
Pain
Injections
Intramuscular Injections
Pressure