Projects per year
Personal profile
Research profile
My research field is molecular bacterial pathogenesis, specifically in bacterial interaction with both the innate and adaptive immune systems. Recently the focus is on the activation of the complement system by Klebsiella pneumoniae in the blood of and the elimination of the bacteria in the bloodstream.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
DMSc, University of Aarhus
Award Date: 27 Apr 1992
PhD, University of Aarhus
Award Date: 27 Jan 1989
MD, University of Copenhagen
Award Date: 30 Jun 1983
Keywords
- Medicine
- Microbiology
- Chlamydia
- Klebsiella
- Immunology
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Collaborations from the last five years
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Projects
- 6 Finished
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Elimination of microorganisms by the innate immune system - Obel Family Foundation - 34260
01/09/2018 → 31/08/2022
Project: Research
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Gastrointestinal biomarkers
Stensballe, A., Andersen, V., Bennike, T. B. & Birkelund, S.
01/09/2014 → 31/08/2016
Project: Research
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Biomarkers in Osteoarthritis
Bennike, T. B., Stensballe, A. & Birkelund, S.
01/09/2012 → 01/09/2015
Project: Research
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Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
Carlsen, T. G. & Birkelund, S.
10/04/2012 → 01/12/2014
Project: Research
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Inflammatory Diseases - Analysis of the Underlying Biological Triggers
Carlsen, T. G., Birkelund, S., Bennike, T. B. & Stensballe, A.
01/12/2011 → 01/12/2014
Project: Research
Research output
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Beta-lactam induced morphological changes in serum of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae blood isolates
Opstrup, K. V., Christiansen, G. & Birkelund, S., Jan 2023, In: Microbes and Infection. 25, 1-2, 105036.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Complement killing of clinical Klebsiella pneumoniae isolates is serum concentration dependent
Opstrup, K. V., Bennike, T. B., Christiansen, G. & Birkelund, S., May 2023, In: Microbes and Infection. 25, 4, 105074.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition
Stensballe, A., Bennike, T. B., Ravn-Haren, G., Mortensen, A., Aboo, C., Knudsen, L. A., Rühlemann, M. C., Birkelund, S., Bang, C., Franke, A., Vogel, U., Hansen, A. K. & Andersen, V., 31 Jul 2023, In: Frontiers in Medicine. 10, 1200317.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile6 Downloads (Pure) -
Lack of neutralization of Chlamydia trachomatis infection by high avidity monoclonal antibodies to surface-exposed major outer membrane protein variable domain IV
Degn, L. L. T., Bech, D., Christiansen, G. & Birkelund, S., Nov 2023, In: Molecular Immunology. 163, p. 163-173 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Downloads (Pure) -
Trypanosoma brucei Invariant Surface gp65 Inhibits the Alternative Pathway of Complement by Accelerating C3b Degradation
Lorentzen, J., Olesen, H. G., Hansen, A. G., Thiel, S., Birkelund, S., Andersen, C. B. F. & Andersen, G. R., 20 Sept 2023, In: Journal of Immunology. 211, 5, p. 862-873 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus)
Datasets
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Additional file 1 of Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Creator), Bennike, T. B. (Creator), Kastaniegaard, K. (Creator), Lausen, M. (Creator), Poulsen, T. B. G. (Creator), Kragstrup, T. W. (Creator), Deleuran, B. W. (Creator), Christiansen, G. (Creator) & Stensballe, A. (Creator), Figshare, 6 Aug 2020
DOI: 10.6084/m9.figshare.12775188.v1, https://springernature.figshare.com/articles/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188/1 and one more link, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/12775188 (show fewer)
Dataset
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Complement deposition on Chlamydia trachomatis
Bennike, T. B. (Creator), Nielsen, M. L. (Creator), Thomsen, M. E. (Creator), Christiansen, G. (Creator), Karred, N. (Creator), Stensballe, A. (Creator) & Birkelund, S. (Creator), PRoteomics IDEntifications Database (PRIDE), 26 May 2020
https://www.ebi.ac.uk/pride/archive/projects/PXD019393
Dataset
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Creator), Bennike, T. B. (Creator), Kastaniegaard, K. (Creator), Lausen, M. (Creator), Poulsen, T. B. G. (Creator), Kragstrup, T. W. (Creator), Deleuran, B. W. (Creator), Christiansen, G. (Creator) & Stensballe, A. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102.v1, https://doi.org/10.6084%2Fm9.figshare.c.5085102.v1
Dataset
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Proteomic analysis of synovial fluid from rheumatic arthritis and spondyloarthritis patients
Birkelund, S. (Creator), Bennike, T. B. (Creator), Kastaniegaard, K. (Creator), Lausen, M. (Creator), Poulsen, T. B. G. (Creator), Kragstrup, T. W. (Creator), Deleuran, B. W. (Creator), Christiansen, G. (Creator) & Stensballe, A. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5085102, https://springernature.figshare.com/collections/Proteomic_analysis_of_synovial_fluid_from_rheumatic_arthritis_and_spondyloarthritis_patients/5085102
Dataset
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Additional file 4: Table S3. of Mass spectrometry analysis of adipose-derived stem cells reveals a significant effect of hypoxia on pathways regulating extracellular matrix
Pennisi, P. (Creator), Stensballe, A. (Creator), Birkelund, S. (Creator), Porsborg, S. R. (Creator), Emmersen, J. (Creator), Fink, T. (Creator) & Zachar, V. (Creator), Figshare, 15 Dec 2016
DOI: 10.6084/m9.figshare.c.3624224_d2.v1, https://doi.org/10.6084%2Fm9.figshare.c.3624224_d2.v1
Dataset
Press/Media
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Læger efterlyser viden om alternativ behandling
17/08/2020
2 items of Media coverage
Press/Media: Press / Media
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Sexologi fylder meget lidt på lægeuddannelsen
Christian Graugaard & Svend Birkelund
24/01/2020
4 items of Media coverage
Press/Media: Press / Media
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Regler for dyreforsøg kan ødelægge patentmuligheder
09/10/2015
1 item of Media coverage
Press/Media: Press / Media
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Gigtforeningen støtter en række nye forskningsprojekter
20/12/2013
2 items of Media coverage
Press/Media: Press / Media