• Hobrovej 18-22, Aalborg Universitetshospital, Syd, Mech-Sense

    9000 Aalborg

    Denmark

  • Denmark

1989 …2019
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Research Output 1989 2019

2019

A Clinical Feasible Method for Computed Tomography-Based Assessment of Sarcopenia in Patients With Chronic Pancreatitis

Ozola-Zālīte, I., Frøkjær, J. B., Mark, E. B., Gudauskas, T., Gudauskas, L., Dedelaite, M., Bieliuniene, E., Ignatavicius, P., Pukitis, A., Drewes, A. M. & Olesen, S. S., 1 Nov 2019, In : Pancreas. 48, 10, p. 1354-1359 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Sarcopenia
Chronic Pancreatitis
Psoas Muscles
Tomography
ROC Curve

A clinically feasible method for the assessment and characterization of pain in patients with chronic pancreatitis

Phillips, A. E., Faghih, M., Kuhlmann, L., Larsen, I. M., Drewes, A. M., Singh, V. K., Yadav, D., Olesen, S. S. & Pancreatic Quantitative Sensory Testing (P-QST) Working Group, 20 Nov 2019, In : Pancreatology.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Pancreatitis
Pain Measurement
Pain
Reference Values
Pressure
Chronic Pancreatitis
Pain
Brain
Linear Models
Gray Matter

Ambulatory assessment of colonic motility using the electromagnetic capsule tracking system: Effect of opioids

Mark, E. B., Klinge, M. W., Grønlund, D., Poulsen, J. L., Schlageter, V., Scott, S. M., Krogh, K. & Drewes, A. M., 12 Nov 2019, In : Neurogastroenterology and Motility Online. e13753.

Research output: Contribution to journalJournal articleResearchpeer-review

Oxycodone
Electromagnetic Phenomena
Opioid Analgesics
Capsules
Placebos
5 Citations (Scopus)

Ambulatory assessment of colonic motility using the electromagnetic capsule tracking system

Mark, E. B., Poulsen, J. L., Haase, A-M., Espersen, M., Gregersen, T., Schlageter, V., Scott, S. M., Krogh, K. & Drewes, A. M., Feb 2019, In : Neurogastroenterology and Motility. 31, 2, 11 p., e13451.

Research output: Contribution to journalJournal articleResearchpeer-review

Electromagnetic Phenomena
Capsules
Diarrhea
Healthy Volunteers
Manometry

Analyzing and benchmarking global consumption statistics for opioid analgesics 2015: Inequality continues to increase

Scholten, W., Christensen, A-E., Olesen, A. E. & Drewes, A. M., 22 Nov 2019, In : Journal of Pain & Palliative Care Pharmacotherapy. p. 1-12 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Benchmarking
Opioid Analgesics
Developed Countries
Pain
Drug and Narcotic Control

A pragmatic utility function to describe the risk-benefit composite of opioid and non-opioid analgesic medication

Olesen, A., Broens, S., Olesen, S., Niesters, M., van Velzen, M., Drewes, A., Dahan, A. & Olofsen, E., 1 Nov 2019, In : The Journal of Pharmacology and Experimental Therapeutics. 371, 2, p. 416-421 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Analgesia
Opioid Analgesics
Analgesics
Dizziness
Pharmacokinetics

Association of multiple patient and disease characteristics with the presence and type of pain in chronic pancreatitis

Olesen, S. S., Kuhlmann, L., Novovic, S., Nøjgaard, C., Kalaitzakis, E., Jensen, N. M., Engjom, T., Dimcevski, G., Waage, A., Haas, S. L., Vujasinovic, M., Riauka, R., Pukitis, A., Ozola-Zālīte, I., Okhlobystin, A., Parhiala, M., Laukkarinen, J., Drewes, A. M. & Scandinavian Baltic Pancreatic Club, 17 Jul 2019, In : Journal of Gastroenterology and Hepatology.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Pancreatitis
Pain
Smoking
Alcohol Drinking
Logistic Models
1 Citation (Scopus)
Peripheral Nervous System Diseases
Type 1 Diabetes Mellitus
Creatine
Spectrum Analysis
Brain
4 Downloads (Pure)

Characterisation of the fibroinflammatory process involved in progression from acute to chronic pancreatitis: study protocol for a multicentre, prospective cohort study

Novovic, S., Borch, A., Werge, M., Karran, D., Gluud, L., Schmidt, P. N., Hansen, E. F., Nøjgaard, C., Jensen, A. B., Jensen, F. K., Frøkjær, J. B., Hansen, M. B., Jørgensen, L. N., Drewes, A. M. & Olesen, S. S., 21 Aug 2019, In : BMJ Open. 9, 8, p. 1-9 9 p., e028999.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Chronic Pancreatitis
Cohort Studies
Prospective Studies
Biomarkers
Oxidative Stress

Chronic abdominal pain and persistent opioid use after bariatric surgery

Simoni, A. H., Ladebo, L., Christrup, L. L., Drewes, A. M., Johnsen, S. P. & Olesen, A. E., 22 Nov 2019, In : Scandinavian Journal of Pain.

Research output: Contribution to journalJournal articleResearchpeer-review

Bariatric Surgery
Chronic Pain
Abdominal Pain
Opioid Analgesics
Pharmacokinetics
5 Citations (Scopus)

Chronic Pancreatitis Is Characterized by Distinct Complication Clusters That Associate With Etiological Risk Factors

Olesen, S. S., Nøjgaard, C., Poulsen, J. L., Haas, S. L., Vujasinovic, M., Löhr, M., Lindkvist, B., Bexander, L., Gulbinas, A., Kalaitzakis, E., Ebrahim, M., Erchinger, F., Engjom, T., Roug, S., Novovic, S., Hauge, T., Waage, A., Laukkarinen, J., Parhiala, M., Pukitis, A. & 3 others, Ozola-Zālīte, I., Drewes, A. M. & Scandinavian Baltic Pancreatic Club, Apr 2019, In : The American Journal of Gastroenterology. 114, 4, p. 656-664 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Pancreatitis
Smoking
Exocrine Pancreatic Insufficiency
Odds Ratio
Confidence Intervals
8 Downloads (Pure)

Cingulate glutamate levels associate with pain in chronic pancreatitis patients

Hansen, T. M., Muthulingam, J. A., Drewes, A. M., Olesen, S. S. & Frøkjær, J. B., 2019, In : NeuroImage: Clinical. 23, p. 101925 6 p., 101925.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Chronic Pancreatitis
Glutamic Acid
Pain
Creatine
Gyrus Cinguli

Circadian rhythm seems intact in patients with type 1 diabetes and autonomic dysfunction and enteropathy

Wegeberg, A. -M. L., Meldgaard, T., Wigh, I. M. N., Sorensen, P. S., Jensen, S. L., Zaugg, V. S., Ejskjaer, N., Drewes, A. M. & Brock, C., 1 Aug 2019, In : Neurogastroenterology and Motility. 31, Suppl. 4, p. 86 1 p., 94.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

1 Citation (Scopus)

Clinical evaluation and treatment of chronic bowel symptoms following cancer in the colon and pelvic organs

Larsen, H. M., Borre, M., Christensen, P., Mohr Drewes, A., Laurberg, S., Krogh, K. & Fassov, J., May 2019, In : Acta Oncologica. 58, 5, p. 776–781 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Colonic Neoplasms
Therapeutics
Bile Acids and Salts
Pelvic Neoplasms
Loperamide
1 Citation (Scopus)

Complications to chronic pancreatitis and etiological risk factors: A continental divide?

Olesen, S. S. & Drewes, A. M., Aug 2019, In : The American Journal of Gastroenterology. 114, 8, p. 1353 1 p.

Research output: Contribution to journalComment/debateResearchpeer-review

1 Citation (Scopus)
3 Downloads (Pure)

Controversies on the endoscopic and surgical management of pain in patients with chronic pancreatitis: pros and cons!

Drewes, A. M., Kempeneers, M. A., Andersen, D. K., Arendt-Nielsen, L., Besselink, M. G., Boermeester, M. A., Bouwense, S., Bruno, M., Freeman, M., Gress, T. M., van Hooft, J. E., Morlion, B., Olesen, S. S., van Santvoort, H., Singh, V. & Windsor, J., Aug 2019, In : Gut. 68, 8, p. 1343-1351 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Cortical networks are disturbed in people with cirrhosis even in the absence of neuropsychometric impairment

Olesen, S. S., Jackson, C. D., Gram, M., Zacharias, H. D., Dirks, M., Weissenborn, K., Drewes, A. M. & Morgan, M. Y., 1 Mar 2019, In : Clinical Neurophysiology. 130, 3, p. 419-427 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Fibrosis
Electroencephalography
Hepatic Encephalopathy
Psychometrics
Neuroglia
3 Downloads (Pure)
Open Access
File
Gastrointestinal Transit
Oxycodone
Healthy Volunteers
Opioid Analgesics
Narcotic Antagonists

Effects of Vortioxetine and Escitalopram on electroencephalographic recordings - A randomized, crossover trial in healthy males

Nissen, T. D., Laursen, B., Viardot, G., ĺHostis, P., Danjou, P., Sluth, L. B., Gram, M., Bastlund, J. F., Christensen, S. R. & Drewes, A. M., 31 Oct 2019, In : Neuroscience.

Research output: Contribution to journalJournal articleResearchpeer-review

Citalopram
Cross-Over Studies
Electroencephalography
Placebos
vortioxetine

Functional gastrointestinal differences in gastric bypass patients using the wireless motility capsule

Ladebo, L., Pedersen, P. V., Brock, C., Drewes, A. M., Christrup, L. L. & Olesen, A. E., 1 Aug 2019, In : Neurogastroenterology and Motility. 31, Suppl. 4, p. 78-79 63.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Investigation of changes in the spatial and temporal brain activity with spinal manipulation – a somatosensory evoked potentials based study

Navid, M. S., Niazi, I. K., Lelic, D., Oliveira, A. D. S. C., Drewes, A. M. & Haavik, H., 2019, Proceedings of the 15th World Federation of Chiropractic Biennial Congress .

Research output: Contribution to book/anthology/report/conference proceedingConference abstract in proceedingResearchpeer-review

Open Access
1 Downloads (Pure)

Liraglutide treatment reduced interleukin 6 in adults with type 1 diabetes but did not improve established autonomic or polyneuropathy

Brock, C., Hansen, C. S., Karmisholt, J., Møller, H. J., Juhl, A., Farmer, A. D., Drewes, A. M., Riahi, S., Lervang, H. H., Jakobsen, P. E. & Brock, B., Nov 2019, In : British Journal of Clinical Pharmacology. 85, 11, p. 2512-2523

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Polyneuropathies
Type 1 Diabetes Mellitus
Interleukin-6
Diabetic Neuropathies
Placebos
4 Citations (Scopus)

Mechanism-based pain management in chronic pancreatitis - is it time for a paradigm shift?

Kuhlmann, L., Olesen, S. S., Olesen, A. E., Arendt-Nielsen, L. & Drewes, A. M., 4 Mar 2019, In : Expert Review of Clinical Pharmacology. 12, 3, p. 249-258 10 p.

Research output: Contribution to journalReview articleResearchpeer-review

Chronic Pancreatitis
Pain Management
Visceral Pain
Nociceptive Pain
Pain

MRI analysis of fecal volume and dryness: Validation study using an experimental oxycodone-induced constipation model

Mark, E. B., Bødker, M. B., Grønlund, D., Østergaard, L. R., Frøkjaer, J. B. & Drewes, A. M., Sep 2019, In : Journal of Magnetic Resonance Imaging. 50, 3, p. 733-745 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Oxycodone
Validation Studies
Constipation
Colon
Placebos
1 Citation (Scopus)

Normal pancreatic volume in adults is influenced by visceral fat, vertebral body width and age

Kipp, J. P., Olesen, S. S., Mark, E. B., Frederiksen, L. C., Drewes, A. M. & Frøkjær, J. B., Mar 2019, In : Abdominal Radiology. 44, 3, p. 958–966 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Intra-Abdominal Fat
Body Composition
Pancreas
Sagittal Abdominal Diameter
Pancreatic Diseases

Normative values for region-specific colonic and gastrointestinal transit times in 111 healthy volunteers using the 3D-Transit electromagnet tracking system: Influence of age, gender, and body mass index

Nandhra, G. K., Mark, E. B., Di Tanna, G. L., Haase, A-M., Poulsen, J., Christodoulides, S., Kung, V., Klinge, M. W., Knudsen, K., Borghammer, P., Andersen, K. O., Fynne, L., Sutter, N., Schlageter, V., Krogh, K., Drewes, A. M., Birch, M. & Scott, S. M., 2019, In : Neurogastroenterology and Motility. e13734.

Research output: Contribution to journalJournal articleResearchpeer-review

Pancreas-specific plasma amylase for assessment and diagnosis of chronic pancreatitis: New insights on an old topic

Olesen, S. S., Krarup, H., Poulsen, J. L., Christensen, J. H., Sheel, A. R. G., Sutton, R., Greenhalf, W., Halloran, C. & Drewes, A. M., Aug 2019, In : United European Gastroenterology Journal. 7, 7, p. 955–964 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Pancreatitis
Amylases
Pancreas
Exocrine Pancreatic Insufficiency
ROC Curve

Pancreatic calcifications associate with diverse aetiological risk factors in patients with chronic pancreatitis: A multicentre study of 1500 cases

Olesen, S. S., Lisitskaya, M. V., Drewes, A. M., Novovic, S., Nøjgaard, C., Kalaitzakis, E., Jensen, N. M., Engjom, T., Erchinger, F., Waage, A., Hauge, T., Haas, S. L., Vujasinovic, M., Lindkvist, B., Zviniene, K., Pukitis, A., Ozola-Zālīte, I., Okhlobystin, A., Parhiala, M., Laukkarinen, J. & 2 others, Frøkjær, J. B. & Scandinavian Baltic Pancreatic Club, Oct 2019, In : Pancreatology. 19, 7, p. 922-928 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Chronic Pancreatitis
Multicenter Studies
Pancreatic Ducts
Sample Size
Multivariate Analysis

Pancreatic exocrine insufficiency in diabetes mellitus - prevalence and characteristics

Søfteland, E., Poulsen, J. L., Starup-Linde, J., Christensen, T. T., Olesen, S. S., Singh, S., Vestergaard, P., Drewes, A. M. & Dimcevski, G., Oct 2019, In : European Journal of Internal Medicine. 68, p. 18-22 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Exocrine Pancreatic Insufficiency
Pancreatic Elastase
Diabetes Mellitus
Breath Tests
Type 1 Diabetes Mellitus
1 Citation (Scopus)
2 Downloads (Pure)

Pathophysiology and management of diabetic gastroenteropathy

Meldgaard, T., Keller, J., Olesen, A. E., Olesen, S. S., Krogh, K., Borre, M., Farmer, A., Brock, B., Brock, C. & Drewes, A. M., 2019, In : Therapeutic Advances in Gastroenterology. 12, 17 p., 1756284819852047.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Pharmacology
Enteric Nervous System
Fecal Incontinence
Polyneuropathies
Dyspepsia
5 Citations (Scopus)

Pathophysiology and management of opioid-induced constipation: European expert consensus statement

Farmer, A. D., Drewes, A., Chiarioni, G., De Giorgio, R., O’Brien, T., Morlion, B. & Tack, J., Feb 2019, In : United European Gastroenterology Journal. 7, 1, p. 7-20 14 p.

Research output: Contribution to journalReview articleResearchpeer-review

Constipation
Opioid Analgesics
Laxatives
Narcotic Antagonists
mu Opioid Receptor
2 Downloads (Pure)

Patient and Disease Characteristics Associate with Sensory Testing Results in Chronic Pancreatitis

Kuhlmann, L., Olesen, S. S., Grønlund, D., Olesen, A. E., Phillips, A. E., Faghih, M. & Drewes, A. M., Sep 2019, In : The Clinical Journal of Pain. 35, 9, p. 786-793 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Chronic Pancreatitis
Pain
Hyperalgesia
Pressure
Visceral Pain

Population pharmacokinetic-pharmacodynamic modelling of liquid and controlled-release formulations of oxycodone in healthy volunteers

Ladebo, L., Foster, D. J. R., Abuhelwa, A. Y., Upton, R. N., Kongstad, K. T., Drewes, A. M., Christrup, L. L. & Olesen, A. E., 9 Oct 2019, In : Basic & Clinical Pharmacology & Toxicology.

Research output: Contribution to journalJournal articleResearchpeer-review

Pharmacodynamics
Oxycodone
Pharmacokinetics
Healthy Volunteers
Liquids
1 Citation (Scopus)
Premedication
Azathioprine
Inflammatory Bowel Diseases
Adrenal Cortex Hormones
Pharmacokinetics
2 Citations (Scopus)

Quantifying the Adequacy of Opioid Analgesic Consumption Globally: An Updated Method and Early Findings

Scholten, W. K., Christensen, A-E., Olesen, A. E. & Drewes, A. M., 1 Jan 2019, In : American Journal of Public Health. 109, 1, p. 52-57 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Opioid Analgesics
Developed Countries
Morphine
Human Development
Nigeria
51 Downloads (Pure)

Quantities of comorbidities affects physical, but not mental health related quality of life in type 1 diabetes with confirmed polyneuropathy

Wegeberg, A-M. L., Meldgaard, T., Hyldahl, S., Jakobsen, P. E., Drewes, A. M., Brock, B. & Brock, C., 15 Feb 2019, In : World Journal of Diabetes. 10, 2, p. 87-95 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Polyneuropathies
Type 1 Diabetes Mellitus
Comorbidity
Mental Health
Quality of Life
4 Citations (Scopus)

Reliability and validity of the new VikingSlice software for computed tomography body composition analysis

Ozola-Zālīte, I., Mark, E. B., Gudauskas, T., Lyadov, V., Olesen, S. S., Drewes, A. M., Pukitis, A. & Frokjær, J. B., 1 Jan 2019, In : European Journal of Clinical Nutrition. 73, 1, p. 54-61 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Body Composition
Reproducibility of Results
Software
Tomography
Adipose Tissue
6 Citations (Scopus)

Repeatability and effect of blinding of fructose breath tests in patients with functional gastrointestinal disorders

Wilder-Smith, C. H., Olesen, S. S., Materna, A. & Drewes, A. M., 1 Feb 2019, In : Neurogastroenterology and Motility Online. 31, 2, e13497.

Research output: Contribution to journalJournal articleResearchpeer-review

Breath Tests
Gastrointestinal Diseases
Fructose
Nocebo Effect
Area Under Curve

Reply

Wilder-Smith, C. H., Olesen, S. S., Materna, A. & Drewes, A. M., 1 Mar 2019, In : Gastroenterology. 156, 4, p. 1221-1222 2 p.

Research output: Contribution to journalComment/debateResearchpeer-review

3 Citations (Scopus)

Sarcopenia associates with increased hospitalization rates and reduced survival in patients with chronic pancreatitis

Olesen, S. S., Büyükuslu, A., Køhler, M., Rasmussen, H. H. & Drewes, A. M., 1 Mar 2019, In : Pancreatology. 19, 2, p. 245-251 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Sarcopenia
Chronic Pancreatitis
Hospitalization
Survival Rate
Exocrine Pancreatic Insufficiency

Smertefysiologi og analgetika

Olesen, A. E., Ladebo, L. & Drewes, A. M., 2019, Basal og klinisk farmakologi. Brøsen, K., Simonsen, U. & Dalhoff, K. (eds.). 6. ed. Roskilde: FADL's Forlag, p. 603-627

Research output: Contribution to book/anthology/report/conference proceedingBook chapterEducationpeer-review

2 Downloads (Pure)
Open Access
File
Chronic Pancreatitis
Vagus Nerve Stimulation
Cross-Over Studies
Clinical Trials
Pain

Symptoms of mast cell activation syndrome in functional gastrointestinal disorders

Wilder-Smith, C. H., Drewes, A. M., Materna, A. & Olesen, S. S., 5 Nov 2019, In : Scandinavian Journal of Gastroenterology. 4 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Gastrointestinal Diseases
Dyspepsia
Mast Cells
Irritable Bowel Syndrome
10 Downloads (Pure)
Open Access
File
Chiropractic Manipulation
Spinal Manipulation
Electromagnetic Phenomena
Tomography
Pain
2 Downloads (Pure)
Open Access
File
Somatosensory Evoked Potentials
Bioelectric potentials
Independent component analysis
Cutoff frequency
Healthy Volunteers

The Incidence of Sexual Dysfunction in Patients With Irritable Bowel Syndrome

Sørensen, J., Schantz Laursen, B., Drewes, A. M. & Krarup, A. L., 8 Oct 2019, In : Sexual Medicine.

Research output: Contribution to journalReview articleResearchpeer-review

Open Access
Irritable Bowel Syndrome
Incidence
Quality of Life
Functional Colonic Diseases
Dyspareunia

The sentinel acute pancreatitis event hypothesis revisited

Olesen, S. S., Drewes, A. M., Novovic, S. & Nøjgaard, C., Jun 2019, In : Pancreatology. 19, 4, p. 614-615 2 p.

Research output: Contribution to journalComment/debateResearchpeer-review

2018
1 Citation (Scopus)

Abnormal neuronal response to rectal and anal stimuli in patients treated with primary radiotherapy for anal cancer

Haas, S., Faaborg, P., Gram, M., Lundby, L., Brock, C., Drewes, A. M., Laurberg, S., Krogh, K. & Christensen, P., 2018, In : Radiotherapy and Oncology. 128, 2, p. 369–374 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Anus Neoplasms
Evoked Potentials
Radiotherapy
Fecal Incontinence
Anal Canal

Ambulatory assessment of colonic motility using the electromagnetic capsule tracking system

Mark, E. B., Poulsen, J. L., Haase, A-M., Espersen, M., Gregersen, T., Schlageter, V., Scott, M., Krogh, K. & Drewes, A. M., 2018, In : Neurogastroenterology and Motility. 30, 1, SI, p. 12 1 p., 067.

Research output: Contribution to journalConference abstract in journalResearchpeer-review