Research output per year
Research output per year
Research output
- 19 results
Search results
-
2023
A novel strategy for delivering Niemann-Pick type C2 proteins across the blood-brain barrier using the brain endothelial-specific AAV-BR1 virus
Rasmussen, C. L. M., Hede, E., Routhe, L. J., Körbelin, J., Helgudottir, S. S., Thomsen, L. B., Schwaninger, M., Burkhart, A. & Moos, T., Jan 2023, In: Journal of Neurochemistry. 164, 1, p. 6-28 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)14 Downloads (Pure) -
The Npc2Gt(LST105)BygNya mouse signifies pathological changes comparable to human Niemann-Pick type C2 disease
Rasmussen, C. L. M., Thomsen, L. B., Heegaard, C. W., Moos, T. & Burkhart, A., Sept 2023, In: Molecular and Cellular Neuroscience. 126, 103880.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
2021
The blood-brain barrier studied in vitro across species
Thomsen, M. S., Humle, N., Hede, E., Moos, T., Burkhart, A. & Thomsen, L. B., 12 Mar 2021, In: PLOS ONE. 16, 3, e0236770.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile24 Citations (Scopus)47 Downloads (Pure) -
2019
Evaluation of Targeted Delivery to the Brain Using Magnetic Immunoliposomes and Magnetic Force
Thomsen, L. B., Linemann, T., Birkelund, S., Tarp, G. A. & Moos, T., 31 Oct 2019, In: Materials. 12, 21, 3576.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)33 Downloads (Pure) -
2018
The endo-lysosomal system of brain endothelial cells is influenced by astrocytes in vitro
Toth, A. E., Siupka, P., P Augustine, T. J., Venø, S. T., Thomsen, L. B., Moos, T., Lohi, H. T., Madsen, P., Lykke-Hartmann, K. & Nielsen, M. S., Nov 2018, In: Molecular Neurobiology. 55, 11, p. 8522-8537 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
11 Citations (Scopus) -
2017
Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells
Siupka, P., Hersom, M. N. S., Lykke-Hartmann, K., Johnsen, K. B., Thomsen, L. B., Andresen, T. L., Moos, T., Abbott, N. J., Brodin, B. & Nielsen, M. S., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 7, p. 2598–2613Research output: Contribution to journal › Journal article › Research › peer-review
17 Citations (Scopus) -
Transfection of primary brain capillary endothelial cells for protein synthesis and secretion of recombinant erythropoietin: a strategy to enable protein delivery to the brain
Larsen, A. B., Andresen, T. L., Aigner, A., Thomsen, L. B. & Moos, T., 2017, In: Cellular and Molecular Life Sciences. 74, 13, p. 2467-2485Research output: Contribution to journal › Journal article › Research › peer-review
11 Citations (Scopus) -
2016
Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier
Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, In: Molecular Neurobiology. 53, 10, p. 7237-7253Research output: Contribution to journal › Journal article › Research › peer-review
71 Citations (Scopus) -
2015
A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes
Thomsen, L. B., Burkhart, A. & Moos, T., 2015, In: PLOS ONE. 10, 8, 16 p., e0134765.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile106 Citations (Scopus)349 Downloads (Pure) -
Targeted drug delivery to the brain using magnetic nanoparticles
Thomsen, L. B., Thomsen, M. S. & Moos, T., 2015, In: Therapeutic Delivery. 6, 10, p. 1145-1155Research output: Contribution to journal › Journal article › Research › peer-review
70 Citations (Scopus) -
Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties
Larsen, A. B., Thomsen, L. B., Thomsen, M. S., Lichota, J., Fazakas, C., Krizbai, I. & Moos, T., 2015, In: Fluids and Barriers of the CNS. 12, 1, 14 p., 19.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile39 Citations (Scopus)344 Downloads (Pure) -
2014
Accessing targeted nanoparticles to the brain: the vascular route
Burkhart, A., Azizi, M., Thomsen, M. S., Thomsen, L. B. & Moos, T., 2014, In: Current Medicinal Chemistry. 21, 36, p. 4092-4099Research output: Contribution to journal › Journal article › Research › peer-review
12 Citations (Scopus) -
2013
Development of a Novel Lipophilic, Magnetic Nanoparticle for in Vivo Drug Delivery
Linemann, T., Thomsen, L. B., du Jardin, K. G., Laursen, J. C., Jensen, J. B., Lichota, J. & Moos, T., 2013, In: Pharmaceutics. 5, 2, p. 246-260Research output: Contribution to journal › Journal article › Research › peer-review
13 Citations (Scopus) -
Uptake and transport of superparamagnetic iron oxide nanoparticles through human brain capillary endothelial cells
Thomsen, L. B., Linemann, T., Pondman, K. M., Lichota, J., Kim, K. S., Pieters, R. J., Visser, G. M. & Moos, T., 2013, In: ACS Chemical Neuroscience. 4, 10, p. 1352-1360Research output: Contribution to journal › Journal article › Research › peer-review
71 Citations (Scopus) -
2012
Brain delivery systems via mechanism independent of receptor-mediated endocytosis and adsorptive-mediated endocytosis
Thomsen, L. B., Lichota, J., Eskehave, T. N., Linemann, T., Mortensen, J. H., du Jardin, K. G. & Moos, T., 2012, In: Current Pharmaceutical Biotechnology. 13, 12, p. 2349-2354Research output: Contribution to journal › Journal article › Research › peer-review
15 Citations (Scopus) -
2011
Gene delivery by pullulan derivatives in brain capillary endothelial cells for protein secretion
Thomsen, L. B., Lichota, J., Kim, K. S. & Moos, T., 2011, In: Journal of Controlled Release. 151, 1, p. 45-50Research output: Contribution to journal › Journal article › Research › peer-review
63 Citations (Scopus) -
Nanoparticle-derived non-viral genetic transfection at the blood-brain barrier to enable neuronal growth factor delivery by secretion from brain endothelium
Thomsen, L. B., Larsen, A. B., Lichota, J. & Moos, T., 2011, In: Current Medicinal Chemistry. 18, 22, p. 3330-3334Research output: Contribution to journal › Journal article › Research › peer-review
10 Citations (Scopus) -
2010
Macromolecular drug transport into the brain using targeted therapy
Lichota, J., Skjørringe, T., Thomsen, L. B. & Moos, T., 2010, In: Journal of Neurochemistry. 113, 1, p. 1-13 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
65 Citations (Scopus) -
Presynaptic calcium signalling in cerebellar mossy fibres
Thomsen, L. B., Jörntell, H. & Midtgaard, J., 2010, In: Frontiers in Neural Circuits. 4, p. Article No. 1 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
6 Citations (Scopus)