Michael Toft Overgaard

MSc, Chemistry-Biotechnology, PhD, Protein Science

Head of Department, Department of Chemistry and Bioscience
Head of Department, The Faculty of Engineering and Science
Professor (with special responsibilities), Section of Biotechnology
Head of Department, Section of Biotechnology
Medical Biotechnology

https://orcid.org/0000-0002-1423-2481

Phone2446 3066, 9940 8525
Emailmto@bio.aau.dk

Fredrik Bajers Vej 7, H, 1-540
9220 Aalborg
Denmark
Frederik Bajers Vej 7H
9220 Aalborg Ø
Denmark

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Personal profile

Keywords

Chemistry and Bioscience
Protein engineering
Recombinant protein production
Proteins
Structure
Functions

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Projects 2017 2023

1 Not started
1 Active

Protein valorization through informatics, hydrolysis, and separation

Gregersen, S., Overgaard, M. T., Hansen, E. B., Bang-Berthelsen, I., Jacobsen, C., García Moreno, P. J. & Marcatili, P.

Department of Chemistry and Bioscience, Faculty of Engineering and Sciences , Aalborg University , Aalborg , Denmark.

01/09/2017 → 30/09/2022

Project: Research

methodology

project

science

Q-BIOPEP: KVANTIFICERING AF BIOAKTIVE FØDEVAREPEPTIDER FRA KARTOFFELPROTEIN

Gregersen, S. & Overgaard, M. T.

Karl Pedersen og Hustrus Industrifond

03/08/2020 → 31/07/2023

Project: Research

peptides

ions

Research Output 1996 2020

89 Journal article
5 Conference abstract for conference
5 Poster
3 Conference abstract in journal
7 More

Emulsifying peptides from potato protein predicted by bioinformatics: Stabilization of fish oil-in-water emulsions

García Moreno, P. J., Jacobsen, C., Marcatili, P., Gregersen, S., Overgaard, M. T., Andersen, M. L., Sørensen, A-D. M. & Hansen, E. B., Apr 2020, In : Food Hydrocolloids. 101, 105529.

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

Fish Oils

Bioinformatics

Emulsions

Stabilization

Peptides

Allostery in Coagulation Factor VIIa Revealed by Ensemble Refinement of Crystallographic Structures

Sorensen, A. B., Madsen, J. J., Frimurer, T. M., Overgaard, M. T., Gandhi, P. S., Persson, E. & Olsen, O. H., 2 Apr 2019, In : Biophysical Journal.

Research output: Contribution to journal › Journal article › Research › peer-review

Factor VIIa

Thromboplastin

Peptide Hydrolases

Trypsin

Disulfides

2 Citations (Scopus)

81 Downloads (Pure)

Ca²⁺ dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

Brohus, M., Søndergaard, M. T., Chen, W. S. R., Van Petegem, F. & Overgaard, M. T., 18 Jan 2019, In : Biochemical Journal. 476, 2, p. 193-209

Research output: Contribution to journal › Journal article › Research › peer-review

Open Access

File

Ryanodine Receptor Calcium Release Channel

Calmodulin

Fluorescence Polarization

Sensors

Clamping devices

Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

Søndergaard, M. T., Liu, Y., Brohus, M., Guo, W., Nani, A., Carvajal, C., Fill, M., Overgaard, M. T. & Chen, S. R. W., 23 Jun 2019, In : F E B S Journal.

Research output: Contribution to journal › Journal article › Research › peer-review

Ryanodine Receptor Calcium Release Channel

Calmodulin

Mutation

HEK293 Cells

Cardiac Arrhythmias

DNA-analyser af rovdyr-ekskrementer på Bornholm

Pagh, S., Lund Nielsen, J., Pertoldi, C. & Overgaard, M. T., 2019, In : Natur på Bornholm. 17, p. 70-73 4 p.

Research output: Contribution to journal › Journal article › Communication

Activities 2010 2019

10 External examination
4 Membership of committees, commissions, boards, councils, associations, organisations, or similar
1 Conference organisation or participation
1 Conference presentations
1 More
- 1 Talks and presentations in private or public companies