Michael Toft Overgaard

MSc, Chemistry-Biotechnology, PhD, Protein Science

  • Fredrik Bajers Vej 7, H, 1-540

    9220 Aalborg

    Denmark

  • Frederik Bajers Vej 7H

    9220 Aalborg Ø

    Denmark

1996 …2023
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Personal profile

Keywords

  • Chemistry and Bioscience
  • Protein engineering
  • Recombinant protein production
  • Proteins
  • Structure
  • Functions

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Projects 2017 2023

Research Output 1996 2020

Emulsifying peptides from potato protein predicted by bioinformatics: Stabilization of fish oil-in-water emulsions

García Moreno, P. J., Jacobsen, C., Marcatili, P., Gregersen, S., Overgaard, M. T., Andersen, M. L., Sørensen, A-D. M. & Hansen, E. B., Apr 2020, In : Food Hydrocolloids. 101, 105529.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Fish Oils
Bioinformatics
Emulsions
Stabilization
Peptides

Allostery in Coagulation Factor VIIa Revealed by Ensemble Refinement of Crystallographic Structures

Sorensen, A. B., Madsen, J. J., Frimurer, T. M., Overgaard, M. T., Gandhi, P. S., Persson, E. & Olsen, O. H., 2 Apr 2019, In : Biophysical Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

Factor VIIa
Thromboplastin
Peptide Hydrolases
Trypsin
Disulfides
2 Citations (Scopus)
81 Downloads (Pure)

Ca2+ dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

Brohus, M., Søndergaard, M. T., Chen, W. S. R., Van Petegem, F. & Overgaard, M. T., 18 Jan 2019, In : Biochemical Journal. 476, 2, p. 193-209

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Ryanodine Receptor Calcium Release Channel
Calmodulin
Fluorescence Polarization
Sensors
Clamping devices

Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

Søndergaard, M. T., Liu, Y., Brohus, M., Guo, W., Nani, A., Carvajal, C., Fill, M., Overgaard, M. T. & Chen, S. R. W., 23 Jun 2019, In : F E B S Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

Ryanodine Receptor Calcium Release Channel
Calmodulin
Mutation
HEK293 Cells
Cardiac Arrhythmias

DNA-analyser af rovdyr-ekskrementer på Bornholm

Pagh, S., Lund Nielsen, J., Pertoldi, C. & Overgaard, M. T., 2019, In : Natur på Bornholm. 17, p. 70-73 4 p.

Research output: Contribution to journalJournal articleCommunication

Activities 2010 2019

Dansk Protein Innovation (External organisation)

Michael Toft Overgaard (Member)
2019 → …

Activity: MembershipsMembership of committees, commissions, boards, councils, associations, organisations, or similar

Thisted Gymnasium (External organisation)

Michael Toft Overgaard (Member (Appointed by AAU))
20192022

Activity: MembershipsMembership of committees, commissions, boards, councils, associations, organisations, or similar

Regulation of autophagy and fibrosis in human ischemic heart disease

Michael Toft Overgaard (External examiner)
1 Sep 2018

Activity: ExaminationExternal examination

Study of PAPP-A and PAPP-A2 in cilia development and the generation of bioactive IGF-II assay

Michael Toft Overgaard (External examiner)
31 Aug 2018

Activity: ExaminationExternal examination

The F141L mutation in human calmodulin disrupts the structure and leads to misregulation of a voltage-gated cardiac calcium channel

Christian Holt (Other), Malene Bredal Brohus (Other), Kaiqian Wang (Other), Filip Van Petegem (Other), Michael Toft Overgaard (Other), Reinhard Wimmer (Lecturer)
19 Aug 201824 Aug 2018

Activity: Talks and presentationsConference presentations

Press / Media

AAU-studerende læser blandt dyrene i Aalborg Zoo

Michael Toft Overgaard & Per Michael Johansen

17/07/2019

3 items of Media coverage

Press/Media: Press / Media

Overkørt rævs ophav stadig ukendt

Michael Toft Overgaard

18/03/2019

1 item of Media coverage

Press/Media: Press / Media

DNA kan afsløre mårhundens oprindelse

Michael Toft Overgaard

06/10/2018

4 items of Media coverage

Press/Media: Press / Media

Millionbevilling styrker biomedicinsk satsning på AAU

Michael Toft Overgaard

16/05/2018

1 item of Media coverage

Press/Media: Press / Media