Research output per year
Research output per year
- 1 - 50 out of 177 results
Search results
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2025
A homo-FRET assay for patatin-specific proteolytic activity
Christensen, L. F., Overgaard, M. T., Hansen, E. B. & Gregersen Echers, S., 15 Jan 2025, In: Food Chemistry. 463, Part 1, 14 p., 141105.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Downloads (Pure) -
CALM1, CALM2, and CALM3expression and translation efficiency provide insight into the severity of calmodulinopathy
Christiansen, S. N. N., Jacobsen, S. B., Andersen, J. D., Cui, Y., Li, W., Crotti, L., Spazzolini, C., Schwartz, P. J., Nyegaard, M. & Overgaard, M. T., 15 May 2025Research output: Other contribution › Research
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CALM1, CALM2, and CALM3 expression and translation efficiency provide insight into the severity of calmodulinopathy
Christiansen, S. N. N., Bøttcher Jacobsen, S., Dyrberg Andersen, J., J. Schwartz, P., Overgaard, M. T. & Nyegaard, M., May 2025.Research output: Contribution to conference without publisher/journal › Poster › Research
File4 Downloads (Pure) -
Extracting proteins from Brewers’ spent grain using emerging technologies: Evaluating efficiency and use as emulsifier
Mikkelsen, R. K., Queiroz, L., Echers, S. G., Hobley, T., Overgaard, M., Jacobsen, C. & Svensson, B., Jun 2025, In: Sustainable Food Proteins. 3, 2, 14 p., e70016.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Downloads (Pure) -
Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans
Sun, B., Ni, M., Li, Y., Song, Z., Wang, H., Zhu, H.-L., Wei, J., Belke, D., Cai, S., Guo, W., Yao, J., Tian, S., Estillore, J. P., Wang, R., Søndergaard, M. T., Brohus, M., Rohde, P. D., Mu, Y., Vallmitjana, A. & Benitez, R. & 10 others, , 25 Mar 2025, In: Circulation. 151, 12, p. 847-862 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Downloads (Pure) -
2024
A Homo-Fret Assay for Patatin-Specific Proteolytic Activity
Christensen, L. F., Overgaard, M. T., Hansen, E. B. & Gregersen, S., 13 Mar 2024, SSRN: Social Science Research Network.Research output: Working paper/Preprint › Preprint
Open Access -
Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca2+ coordinating residues.
Holler, C. V., Petersson, N. M., Brohus, M., Niemelä, M. A., Iversen, E. D., Overgaard, M. T., Iwaï, H. & Wimmer, R., Jan 2024, In: Cell Calcium. 117, 10 p., 102831.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile26 Downloads (Pure) -
Brown Bears activates a Satiety Hormone Cholecystokinin (CCK) pathway in adipose tissue during hibernation
Henriksen, T. I., Engelhard, C., Frøbert, A., Schrölkamp, M., Friebe, A., Overgaard, M., Poulsen, S., Rehfeld, J., Nielsen, J., Fröbert, O., Scheele, C., Feizi, A. & Nielsen, S., 21 Dec 2024, bioRxiv.Research output: Working paper/Preprint › Preprint
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Calmodulin, sudden death, and the Folbigg case: genes in court
Schwartz, P. J., Crotti, L., Nyegaard, M. & Overgaard, M. T., 27 May 2024, In: European Heart Journal. 45, 20, p. 1801-1803 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
3 Citations (Scopus) -
Calmodulin variants in schizophrenia patients display gain-offunction or loss-of-function effects
Jensen, H. H., Brohus, M. B., W. Hussey, J., Busuioc, A.-O., Iversen, E. D., Darki, F., Nikolova, G. D., Baisgaard, A. E., Rohde, P. D., Holm, I. E. G., McQuillin, A., Moos, T., E. Dick, I., Overgaard, M. T. & Nyegaard, M., 26 May 2024, medRxiv, 27 p.Research output: Working paper/Preprint › Preprint
Open Access -
Decoding the Impact of Neighboring Amino Acid on ESI-MS Intensity Output through Deep Learning
Abdul-Khalek, N., Wimmer, R., Overgaard, M. T. & Echers, S. G., 6 Feb 2024, bioRxiv, 28 p.Research output: Working paper/Preprint › Preprint
Open AccessFile3 Downloads (Pure) -
Decoding the impact of neighboring amino acids on ESI-MS intensity output through deep learning
Abdul-Khalek, N., Wimmer, R., Overgaard, M. T. & Gregersen Echers, S., 30 Oct 2024, In: Journal of Proteomics. 309, 105322.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)16 Downloads (Pure) -
Extracting proteins from Brewers’ spent grain using emerging technologies: Evaluating efficiency and use as emulsifier
Mikkelsen, R. K., Queiroz, L., Echers, S. G., Hobley, T., Overgaard, M., Jacobsen, C. & Svensson, B., 1 Nov 2024, Authorea, 17 p.Research output: Working paper/Preprint › Preprint
Open Access -
Role of Calmodulin in Cardiac Disease: Insights on Genotype and Phenotype
Schwartz, P. J., Crotti, L., Nyegaard, M. & Overgaard, M. T., Oct 2024, In: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 17, 5, p. e004542 e004542.Research output: Contribution to journal › Review article › peer-review
1 Citation (Scopus) -
To fly, or not to fly, that is the question: A deep learning model for peptide detectability prediction in mass spectrometry
Abdul-Khalek, N., Picciani, M., Wimmer, R., Overgaard, M. T., Wilhelm, M. & Echers, S. G., 31 Oct 2024, bioRxiv, 31 p.Research output: Working paper/Preprint › Preprint
Open AccessFile15 Downloads (Pure) -
2023
Addendum to the report dated October 18th, 2022 Report on analysis of the Folbigg CALM2 G114R mutation and its impact on calmodulin protein function: – prepared in connection with the 2022 Folbigg Inquiry
Overgaard, M. T. & Nyegaard, M., 15 Jan 2023, 15 p.Research output: Book/Report › Report › Commissioned
File81 Downloads (Pure) -
Antioxidant peptides from alternative sources reduce lipid oxidation in 5% fish oil-in-water emulsions (pH 4) and fish oil-enriched mayonnaise
Varona, E., García-Moreno, P. J., Echers, S. G., Olsen, T. H., Marcatili, P., Guardiola, F., Overgaard, M. T., Hansen, E. B., Jacobsen, C. & Yesiltas, B., 15 Nov 2023, In: Food Chemistry. 426, 136498.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)80 Downloads (Pure) -
Bioinformatically predicted emulsifying peptides and potato protein hydrolysate improves the oxidative stability of microencapsulated fish oil
Bjørlie, M., Yesiltas, B., García Moreno, P. J., Carpio, F. J. E., Rahmani-Manglano, N. E., Guadix, E. M., Jafarpour, A., Hansen, E. B., Marcatili, P., Overgaard, M. T., Echers, S. G. & Jacobsen, C., Dec 2023, In: Food Chemistry Advances. 3, 100441.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile4 Citations (Scopus)44 Downloads (Pure) -
Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain
Brohus, M., Busuioc, A.-O., Wimmer, R., Nyegaard, M. & Overgaard, M. T., 16 Aug 2023, In: Frontiers in Pharmacology. 14, 1210140.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile7 Citations (Scopus)85 Downloads (Pure) -
Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry
Crotti, L., Spazzolini, C., Nyegaard, M., Overgaard, M. T., Kotta, M.-C., Dagradi, F., Sala, L., Aiba, T., Ayers, M. D., Baban, A., Barc, J., Beach, C. M., Behr, E. R., Bos, J. M., Cerrone, M., Covi, P., Cuneo, B., Denjoy, I., Donner, B. & Elbert, A. & 35 others, , 14 Sept 2023, In: European Heart Journal. 44, 35, p. 3357-3370 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile35 Citations (Scopus)151 Downloads (Pure) -
Disease-associated calmodulin variants impair regulation of neuronal voltage-gated calcium channels
Hussey, J. W., DeMarco, E., DiSilvestre, D., Jensen, H. H., Ben-Johny, M., Nyegaard, M., Overgaard, M. T. & Dick, I. E., 10 Feb 2023, In: Biophysical Journal. 122, 3, Suppl. 1, p. 105aResearch output: Contribution to journal › Conference abstract in journal › Research
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Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans
Jensen, H. H., Frantzen, M. T., Wesseltoft, J. L., Busuioc, A.-O., Møller, K. V., Brohus, M., Duun, P. R., Nyegaard, M., Overgaard, M. T. & Olsen, A., 15 Jun 2023, In: Human Molecular Genetics. 32, 12, p. 2068-2083 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Citations (Scopus)123 Downloads (Pure) -
Hypothyroidism in hibernating brown bears
Frøbert, A. M., Nielsen, C. G., Brohus, M., Kindberg, J., Fröbert, O. & Overgaard, M. T., 1 Feb 2023, In: Thyroid research. 16, 1, 3.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile3 Citations (Scopus)105 Downloads (Pure) -
Insight on Physicochemical Properties Governing Peptide MS1 Response in HPLC-ESI-MS/MS: A Deep Learning Approach
Abdul-Khalek, N., Wimmer, R., Overgaard, M. T. & Echers, S. G., 27 Jul 2023, In: Computational and Structural Biotechnology Journal. 21, p. 3715-3727 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile5 Citations (Scopus)87 Downloads (Pure) -
Insight on physicochemical properties governing peptide MS1 response in HPLC-ESI-MS/MS proteomics: A deep learning approach
Khalek, N. A., Wimmer, R., Overgaard, M. T. & Echers, S. G., 13 Feb 2023, bioRxiv, 32 p.Research output: Working paper/Preprint › Preprint
Open Access -
Physical and oxidative stability of fish oil-in-water emulsions stabilized with emulsifier peptides derived from seaweed, methanotrophic bacteria and potato proteins
Yesiltas, B., Caindec, A. M. S., García Moreno, P. J., Echers, S. G., Hegelund Olsen, T., Jones, N. C., Hoffmann, S. V., Marcatili, P., Overgaard, M. T., Hansen, E. B. & Jacobsen, C., 20 Apr 2023, In: Colloids and Surfaces A: Physicochemical and Engineering Aspects. 663, 131069.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)52 Downloads (Pure) -
Provision of additional material including comments to evidence of Prof. MacRae: – prepared in connection with the 2023 Folbigg Inquiry
Overgaard, M. T. & Nyegaard, M., 1 Mar 2023, 14 p.Research output: Book/Report › Report › Commissioned
File48 Downloads (Pure) -
Recent advances in the production of emulsifying peptides with the aid of proteomics and bioinformatics
Moreno, P. J. G., Yesiltas, B., Echers, S. G., Marcatili, P., Overgaard, M. T., Hansen, E. B. & Jacobsen, C., Jun 2023, In: Current Opinion in Food Science. 51, 101039.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)87 Downloads (Pure) -
Report on analysis of the Folbigg CALM2 G114R mutation and its impact on calmodulin protein function: – prepared in connection with the 2022 Folbigg Inquiry
Overgaard, M. T. & Nyegaard, M., 15 Jan 2023, 17 p.Research output: Book/Report › Report › Communication
File198 Downloads (Pure) -
Targeted hydrolysis of native potato protein: A novel workflow for obtaining hydrolysates with improved interfacial properties
Gregersen Echers, S., Jafarpour, A., Yesiltas, B., García Moreno, P. J., Greve-Poulsen, M., Hansen, D. K., Jacobsen, C., Overgaard, M. T. & Hansen, E. B., Apr 2023, In: Food Hydrocolloids. 137, 108299.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Citations (Scopus)122 Downloads (Pure) -
2022
A gain-of-function mutation in the ITPR1 gating domain causes male infertility in mice
Sun, B., Ni, M., Tian, S., Guo, W., Cai, S., Sondergaard, M. T., Chen, Y., Mu, Y., Estillore, J. P., Wang, R., Chen, J., Overgaard, M. T., Fill, M., Ramos-Franco, J., Nyegaard, M. & Wayne Chen, S. R., Aug 2022, In: Journal of cellular physiology. 237, 8, p. 3305-3316 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
9 Citations (Scopus) -
Antioxidant peptides derived from potato, seaweed, microbial and spinach proteins: Oxidative stability of 5% fish oil-in-water emulsions
Yesiltas, B., García Moreno, P. J., Gregersen Echers, S., Olsen, T. H., Jones, N. C., Hoffmann, S. V., Marcatili, P., Overgaard, M. T., Hansen, E. B. & Jacobsen, C., 15 Aug 2022, In: Food Chemistry. 385, 13 p., 132699.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile52 Citations (Scopus)117 Downloads (Pure) -
Antioxidant peptides from alternative sources reduce lipid oxidation in 5% fish oil-in-water 2 emulsions (pH 4) and fish oil-enriched mayonnaise
Varona, E., García Moreno, P. J., Gregersen Echers, S., Olsen, T. H., Marcatili, P., Guardiola, F., Overgaard, M. T., Hansen, E. B., Jacobsen, C. & Yesiltas, B., 16 Nov 2022, SSRN: Social Science Research Network.Research output: Working paper/Preprint › Preprint
File86 Downloads (Pure) -
A potent peptide emulsifier from potato storage proteins and its natural isoforms: Insight into the structure/function relationship of amphipathic, α-helical peptide emulsifiers, their targeted release, and applicability.
Gregersen Echers, S., García Moreno, P. J., Yesiltas, B., Jafarpour, A., Bjørlie, M., Hansen, E. B., Marcatili, P., Jacobsen, C., Jones, N. C., Hoffmann, S. V., Wimmer, R. & Overgaard, M. T., 11 Apr 2022.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
Open AccessFile59 Downloads (Pure) -
A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa
Sorensen, A. B., Greisen, P. J., Madsen, J. J., Lund, J., Andersen, G., Wulff-Larsen, P. G., Pedersen, A. A., Gandhi, P. S., Overgaard, M. T., Østergaard, H. & Olsen, O. H., 8 Mar 2022, In: Scientific Reports. 12, 1, 3747.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)51 Downloads (Pure) -
Bioinformatically predicted emulsifying peptides and potato protein hydrolysate improves the oxidative stability of microencapsulated fish oil
Bjørlie, M., Yesiltas, B., García Moreno, P. J., Javier, E.-C., Rahmani-Manglano, N. E., Gaudix, E., Jafarpour, A., Hansen, E. B., Marcatili, P., Overgaard, M. T., Gregersen Echers, S. & Jacobsen, C., 20 Nov 2022, bioRxiv.Research output: Working paper/Preprint › Preprint
Open Access -
Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin
Frøbert, A. M., Brohus, M., Toews, J. N. C., Round, P., Fröbert, O., Hammond, G. L. & Overgaard, M. T., Feb 2022, In: FEBS open bio. 12, 2, p. 362-378 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)145 Downloads (Pure) -
Circulating insulin-like growth factor system adaptations in hibernating brown bears indicate increased tissue IGF availability
Frøbert, A. M., Brohus, M., Roesen, T. S., Kindberg, J., Fröbert, O., Conover, C. A. & Overgaard, M. T., 1 Sept 2022, In: American Journal of Physiology: Endocrinology and Metabolism. 323, 3, p. E307-E318Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats
Frøbert, A. M., Toews, J. N. C., Nielsen, C. G., Brohus, M., Kindberg, J., Jessen, N., Fröbert, O., Hammond, G. L. & Overgaard, M. T., 1 Sept 2022, In: Physiological and Biochemical Zoology. 95, 5, p. 365-378 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
2 Citations (Scopus) -
Is Gigartina a potential source of food protein and functional peptide-based ingredients? Evaluating an industrial, pilot-scale extract by proteomics and bioinformatics
Gregersen Echers, S., Abdul-Khalek, N., Mikkelsen, R. K., Holdt, S. L., Jacobsen, C., Hansen, E. B., Olsen, T. H., Sejberg, J. J. P. & Overgaard, M. T., Dec 2022, In: Future Foods. 6, 100189.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile11 Citations (Scopus)223 Downloads (Pure) -
Peptide emulsifiers from potato: Structure/function and targeted release
Gregersen Echers, S., García Moreno, P. J., Yesiltas, B., Jafarpour, A., Bjørlie, M., Hansen, E. B., Marcatili, P., Jacobsen, C., Jones, N. C., Hoffmann, S. V., Wimmer, R. & Overgaard, M. T., 22 Sept 2022.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
Open AccessFile19 Downloads (Pure) -
Plasma proteomics data from hibernating and active Scandinavian brown bears
Frøbert Harbo, A. M., Gregersen Echers, S., Brohus, M., Welinder, K. G., Kindberg, J., Fröbert, O. & Overgaard, M. T., Apr 2022, In: Data in Brief. 41, 107959.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)68 Downloads (Pure) -
Production of emulsifying peptides from seaweed protein by enzymatic hydrolysis
Mikkelsen, R. K., Yesiltas, B., Gregersen Echers, S., Overgaard, M. T., Marcatili, P., Hansen, E. B. & Jacobsen, C., 22 Sept 2022.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Proteomic characterization of pilot scale hot-water extracts from the industrial carrageenan red seaweed Eucheuma denticulatum
Gregersen Echers, S., Pertseva, M., Marcatili, P., Holdt, S. L., Jacobsen, C., García Moreno, P. J., Hansen, E. B. & Overgaard, M. T., Mar 2022, In: Algal Research. 62, 15 p., 102619.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)65 Downloads (Pure) -
Targeted hydrolysis of native potato protein: A novel route for obtaining hydrolysates with improved interfacial properties
Gregersen Echers, S., Jafarpour, A., Yesiltas, B., García Moreno, P. J., Greve-Poulsen, M., Hansen, D. K., Jacobsen, C., Overgaard, M. T. & Hansen, E. B., 25 May 2022, bioRxiv.Research output: Working paper/Preprint › Preprint
Open Access -
2021
Applying Quantitative Proteomics for Evaluation of Protein Quality, Nutritional Value, and Extraction Methods in Side-Streams of Industrial Carrageenan Production from the Red Seaweed Eucheuma denticulatum (Spinosum)
Gregersen Echers, S., Yesiltas, B., García Moreno, P. J., Naseri, A., Holdt, S. L., Jacobsen, C., Hansen, E. B., Marcatili, P. & Overgaard, M. T., 1 Oct 2021.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
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Characterizing patatin specific protease activity by high-throughput homo-FRET assay and mass spectrometry
Friis Christensen, L., Gregersen Echers, S., Overgaard, M. T. & Hansen, E. B., 1 Oct 2021.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
Open AccessFile103 Downloads (Pure) -
Emulsifier peptides derived from seaweed, methanotrophic bacteria, and potato proteins identified by quantitative proteomics and bioinformatics
Yesiltas, B., Gregersen Echers, S., Lægsgaard, L., Brinch, M. L., Olsen, T. H., Marcatili, P., Overgaard, M. T., Hansen, E. B., Jacobsen, C. & García-Moreno, P. J., 15 Nov 2021, In: Food Chemistry. 362, 12 p., 130217.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile33 Citations (Scopus)75 Downloads (Pure) -
Infanticide vs. inherited cardiac arrhythmias
Brohus, M., Arsov, T., Wallace, D. A., Jensen, H. H., Nyegaard, M., Crotti, L., Adamski, M., Zhang, Y., Field, M. A., Athanasopoulos, V., Baró, I., Ribeiro de Oliveira-Mendes, B. B., Redon, R., Charpentier, F., Raju, H., DiSilvestre, D., Wei, J., Wang, R., Rafehi, H. & Kaspi, A. & 7 others, , Mar 2021, In: Europace. 23, 3, p. 441-450 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile29 Citations (Scopus)86 Downloads (Pure) -
Microbial proteins: Moving from feed to food applications aided by proteomics and bioinformatics
Gregersen Echers, S., Yesiltas, B., García Moreno, P. J., Hegelund Olsen, T., Marcatili, P., Jacobsen, C., Hansen, E. B., Ntokou, E., Christensen, I. & Overgaard, M. T., 1 Oct 2021.Research output: Contribution to conference without publisher/journal › Conference abstract for conference › Research › peer-review
Open AccessFile186 Downloads (Pure)