Mads Toft Søndergaard

  • Fredrik Bajers Vej 7, H, 3536

    9220 Aalborg

    Denmark

20102019
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Calmodulin Medicine & Life Sciences
Ryanodine Receptor Calcium Release Channel Medicine & Life Sciences
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Research Output 2010 2019

  • 12 Journal article
  • 3 Conference abstract for conference
3 Citations (Scopus)
95 Downloads (Pure)

Ca2+ dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

Brohus, M., Søndergaard, M. T., Chen, W. S. R., Van Petegem, F. & Overgaard, M. T., 18 Jan 2019, In : Biochemical Journal. 476, 2, p. 193-209

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Ryanodine Receptor Calcium Release Channel
Calmodulin
Fluorescence Polarization
Sensors
Clamping devices
1 Citation (Scopus)

Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

Søndergaard, M. T., Liu, Y., Brohus, M., Guo, W., Nani, A., Carvajal, C., Fill, M., Overgaard, M. T. & Chen, S. R. W., 23 Jun 2019, In : F E B S Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

Ryanodine Receptor Calcium Release Channel
Calmodulin
Mutation
HEK293 Cells
Cardiac Arrhythmias

Role of cardiac ryanodine receptor calmodulin-binding domains in mediating the action of arrhythmogenic calmodulin N-domain mutation N54I

Søndergaard, M. T., Liu, Y., Guo, W., Wei, J., Wang, R., Brohus, M., Overgaard, M. T. & Chen, S. R. W., 25 Nov 2019, In : The FEBS Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

Ryanodine Receptor Calcium Release Channel
Calmodulin
Mutation
HEK293 Cells
12 Citations (Scopus)

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

Søndergaard, M. T., Liu, Y., Larsen, K. T., Nani, A., Tian, X., Holt, C., Wang, R., Wimmer, R., Van Petegem, F., Fill, M., Chen, S. R. W. & Overgaard, M. T., Jan 2017, In : Journal of Biological Chemistry. 292, p. 1385-1395 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Ryanodine Receptor Calcium Release Channel
Calmodulin
Mutation
20 Citations (Scopus)

Epigallocatechin gallate remodels overexpressed functional amyloids in pseudomonas aeruginosa and increases biofilm susceptibility to antibiotic treatment

Stenvang, M. R., Dueholm, M. S., Vad, B. S., Seviour, T., Zeng, G., Geifman-Shochat, S., Søndergaard, M. T., Christiansen, G., Meyer, R. L., Kjelleberg, S., Nielsen, P. H. & Otzen, D. E., 16 Dec 2016, In : The Journal of Biological Chemistry. 291, 51, p. 26540-26553 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Biofilms
Amyloid
Pseudomonas aeruginosa
Anti-Bacterial Agents
Quorum Sensing