Mads Toft Søndergaard

  • Fredrik Bajers Vej 7, H, 3536

    9220 Aalborg

    Denmark

20102019

Research output per year

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Research Output

  • 12 Journal article
  • 3 Conference abstract for conference
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Journal article
Journal article

Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-Mediated Ca2+ Release

Søndergaard, M. T., Tian, X., Liu, Y., Wang, R., Chazin, W. J., Chen, S. R. W. & Overgaard, M. T., 23 Oct 2015, In : Journal of Biological Chemistry. 290, 43, p. 26151-26162 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

29 Citations (Scopus)

Ca2+ dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

Brohus, M., Søndergaard, M. T., Chen, W. S. R., Van Petegem, F. & Overgaard, M. T., 18 Jan 2019, In : Biochemical Journal. 476, 2, p. 193-209 17 p.

Research output: Contribution to journalJournal article

Open Access
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4 Citations (Scopus)
121 Downloads (Pure)

Calmodulin in a Heartbeat

Sorensen, A. B., Søndergaard, M. T. & Overgaard, M. T., 13 May 2013, In : F E B S Journal. 280, 21, p. 5511-5532

Research output: Contribution to journalJournal articleResearchpeer-review

38 Citations (Scopus)

Calmodulin mutations causing catecholaminergic polymorphic ventricular tachycardia confer opposing functional and biophysical molecular changes

Søndergaard, M. T., Sorensen, A. B., Skov, L. L., Kjaer-Sorensen, K., Bauer, M. C., Nyegaard, M., Linse, S., Oxvig, C. & Overgaard, M. T., 14 Jan 2015, In : F E B S Journal. 282, 4, p. 803-816 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

25 Citations (Scopus)

Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations

Søndergaard, M. T., Liu, Y., Brohus, M., Guo, W., Nani, A., Carvajal, C., Fill, M., Overgaard, M. T. & Chen, S. R. W., Nov 2019, In : F E B S Journal. 286, 22, p. 4554-4578 25 p.

Research output: Contribution to journalJournal article

3 Citations (Scopus)

Epigallocatechin gallate remodels overexpressed functional amyloids in pseudomonas aeruginosa and increases biofilm susceptibility to antibiotic treatment

Stenvang, M. R., Dueholm, M. S., Vad, B. S., Seviour, T., Zeng, G., Geifman-Shochat, S., Søndergaard, M. T., Christiansen, G., Meyer, R. L., Kjelleberg, S., Nielsen, P. H. & Otzen, D. E., 16 Dec 2016, In : The Journal of Biological Chemistry. 291, 51, p. 26540-26553 14 p.

Research output: Contribution to journalJournal article

Open Access
21 Citations (Scopus)

Expression of Fap amyloids in Pseudomonas aeruginosa, P. fluorescens, and P. putida results in aggregation and increased biofilm formation

Dueholm, M. S., Søndergaard, M. T., Nilsson, M., Christiansen, G., Stensballe, A., Overgaard, M. T., Givskov, M. C., Tolker-Nielsen, T., Otzen, D. E. & Nielsen, P. H., 18 Mar 2013, In : MicrobiologyOpen. 2, 3, p. 365-382

Research output: Contribution to journalJournal article

69 Citations (Scopus)

Heparin binding mechanism of the insulin-like growth factor (IGF) 2 / IGF binding protein 2 complex

Lund, J., Sondergaard, M. T., Conover, C. A. & Overgaard, M. T., 6 Mar 2014, In : Journal of Molecular Endocrinology. 52, 3, p. 345-355

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
11 Citations (Scopus)
18 Citations (Scopus)

Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death

Nyegaard, M., Overgaard, M. T., Sondergaard, M. T., Vranas, M., Behr, E. R., Hildebrandt, L. L., Lund, J., Hedley, P. L., Camm, A. J., Wettrell, G., Fosdal, I., Christiansen, M. & Borglum, A. D., 2012, In : American Journal of Human Genetics. 91, 4, p. 703-712 10 p.

Research output: Contribution to journalJournal article

203 Citations (Scopus)

Role of cardiac ryanodine receptor calmodulin-binding domains in mediating the action of arrhythmogenic calmodulin N-domain mutation N54I

Søndergaard, M. T., Liu, Y., Guo, W., Wei, J., Wang, R., Brohus, M., Overgaard, M. T. & Chen, S. R. W., 25 Nov 2019, In : The FEBS Journal.

Research output: Contribution to journalJournal articleResearchpeer-review

The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+-binding but not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor

Søndergaard, M. T., Liu, Y., Larsen, K. T., Nani, A., Tian, X., Holt, C., Wang, R., Wimmer, R., Van Petegem, F., Fill, M., Chen, S. R. W. & Overgaard, M. T., Jan 2017, In : Journal of Biological Chemistry. 292, p. 1385-1395 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
14 Citations (Scopus)