Photo of Annette Burkhart Larsen

Annette Burkhart Larsen

Kandidat i Medicin med Industriel Specialisering - Biomedicin

  • Fredrik Bajers Vej 7, D, D2-111

    9220 Aalborg Ø

    Denmark

20112019
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Research Output 2011 2019

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Journal article
2019
1 Citation (Scopus)
Hepcidins
PC12 Cells
Iron
Messenger RNA
Deferoxamine
8 Citations (Scopus)

Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor-targeted gold nanoparticles and liposomal cargo

Johnsen, K. B., Bak, M., Melander, F., Thomsen, M. S., Burkhart, A., Kempen, P. J., Andresen, T. L. & Moos, T., 10 Feb 2019, In : Journal of Controlled Release. 295, p. 237-249 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Transferrin Receptors
Blood-Brain Barrier
Gold
Nanoparticles
Antibodies
2018
12 Citations (Scopus)
538 Downloads (Pure)

Antibody affinity and valency impact brain uptake of transferrin receptor-targeted gold nanoparticles

Johnsen, K. B., Bak, M., Kempen, P. J., Melander, F., Burkhart, A., Thomsen, M. S., Nielsen, M. S., Moos, T. & Andresen, T. L., 2018, In : Theranostics. 8, 12, p. 3416-3436

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Transferrin Receptors
Antibody Affinity
Gold
Nanoparticles
Nanomedicine
2017
13 Citations (Scopus)
Endothelial cells
Pericytes
Blood-Brain Barrier
Basement Membrane
Brain
36 Citations (Scopus)
44 Downloads (Pure)

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Johnsen, K. B., Burkhart, A., Melander, F., Kempen, P. J., Vejlebo, J. B., Siupka, P., Nielsen, M. S., Andresen, T. L. & Moos, T., 1 Dec 2017, In : Scientific Reports. 7, 13 p., 10396.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Transferrin Receptors
Blood-Brain Barrier
Brain
Endothelium
Transcytosis
2 Citations (Scopus)
Erythropoietin
Transfection
Endothelial Cells
Brain
Proteins
2016
26 Citations (Scopus)

Expression of iron-related proteins at the neurovascular unit supports reduction and reoxidation of iron for transport through the blood-brain barrier

Burkhart, A., Skjørringe, T., Johnsen, K. B., Siupka, P., Thomsen, L. B., Nielsen, M. S., Thomsen, L. L. & Moos, T., 2016, In : Molecular Neurobiology. 53, 10, p. 7237-7253

Research output: Contribution to journalJournal articleResearchpeer-review

Blood-Brain Barrier
Iron
Ceruloplasmin
Brain
Endothelial Cells
2015
50 Citations (Scopus)
211 Downloads (Pure)

A triple culture model of the blood-brain barrier using porcine brain endothelial cells, astrocytes and pericytes

Thomsen, L. B., Burkhart, A. & Moos, T., 2015, In : PLOS ONE. 10, 8, 16 p., e0134765.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Pericytes
blood-brain barrier
astrocytes
Endothelial cells
Blood-Brain Barrier
52 Citations (Scopus)
212 Downloads (Pure)
Open Access
File
20 Citations (Scopus)
239 Downloads (Pure)

Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties

Larsen, A. B., Thomsen, L. B., Thomsen, M. S., Lichota, J., Fazakas, C., Krizbai, I. & Moos, T., 2015, In : Fluids and Barriers of the CNS. 12, 1, 14 p., 19.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Blood-Brain Barrier
Transfection
Endothelial Cells
Brain
Astrocytes
2014
8 Citations (Scopus)

Accessing targeted nanoparticles to the brain: the vascular route

Burkhart, A., Azizi, M., Thomsen, M. S., Thomsen, L. B. & Moos, T., 2014, In : Current Medicinal Chemistry. 21, 36, p. 4092-4099

Research output: Contribution to journalJournal articleResearchpeer-review

2011
8 Citations (Scopus)