20032020

Research output per year

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Journal article
2020
Open Access
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36 Downloads (Pure)

Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact

Schönherz, A. A., Bødker, J. S., Schmitz, A., Brøndum, R. F., Jakobsen, L. H., Roug, A. S., Severinsen, M. T., El-Galaly, T. C., Jensen, P., Johnsen, H. E., Bøgsted, M. & Dybkær, K., Apr 2020, In : PLOS ONE. 15, 4, p. 1-21 21 p., e0229593.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
36 Downloads (Pure)
2019

High CXCR4 expression impairs rituximab response and the prognosis of R-CHOP-treated diffuse large B-cell lymphoma patients

Laursen, M. B., Reinholdt, L., Schönherz, A. A., Due, H., Jespersen, D. S., Grubach, L., Ettrup, M. S., Røge, R., Falgreen, S., Sørensen, S., Bødker, J. S., Schmitz, A., Johnsen, H. E., Bøgsted, M. & Dybkær, K., 22 Jan 2019, In : Oncotarget. 10, 7, p. 717-731 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
7 Citations (Scopus)
87 Downloads (Pure)

I 2039 kan myelomatose helbredes

Jørgensen, N. G., Kristensen, I. B., Bødker, J. S., Krejcik, J., Dimopoulos, K. & Andersen, M. N., Mar 2019, In : Myelomatosebladet. Marts 2019, Jubilæumsnummer 1999-2019, p. 16-21 6 p.

Research output: Contribution to journalJournal articleCommunication

Open Access
2018

A multiple myeloma classification system that associates normal B-cell subset phenotypes with prognosis

Bødker, J. S., Brøndum, R. F., Schmitz, A., Schönherz, A. A., Jespersen, D. S., Sønderkær, M., Vesteghem, C., Due, H., Nørgaard, C. H., Perez-Andres, M., Samur, M. K., Davies, F., Walker, B., Pawlyn, C., Kaiser, M., Johnson, D., Bertsch, U., Broyl, A., van Duin, M., Shah, R. & 12 others, Johansen, P., Nørgaard, M. A., Samworth, R. J., Sonneveld, P., Goldschmidt, H., Morgan, G. J., Orfao, A., Munshi, N., Johnsen, H. E., El-Galaly, T., Dybkær, K. & Bøgsted, M., 2018, In : Blood advances. 2, 18, p. 2400-2411 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
1 Citation (Scopus)

Oral mucosa tissue gene expression profiling before, during, and after radiation therapy for tonsil squamous cell carcinoma

Marcussen, M., Sønderkær, M., Bødker, J. S., Andersen, M., Nielsen, S., Vesteghem, C., Christiansen, I., Bergmann, O. J., Bøgsted, M., Dybkær, K., Vyberg, M. & Johnsen, H. E., 2018, In : PLOS ONE. 13, 1, 16 p., e0190709.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
4 Citations (Scopus)
144 Downloads (Pure)

Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow – A proof of concept study

Nørgaard, C. H., Jakobsen, L. H., Gentles, A. J., Dybkær, K., El-Galaly, T. C., Bødker, J. S., Schmitz, A., Johansen, P., Herold, T., Spiekermann, K., Brown, J. R., Klitgaard, J. L., Johnsen, H. E. & Bøgsted, M., 1 Mar 2018, In : PLOS ONE. 13, 3, p. e0193249 15 p., e0193249.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
3 Citations (Scopus)
220 Downloads (Pure)
2017

Immunoparesis in newly diagnosed Multiple Myeloma patients: Effects on overall survival and progression free survival in the Danish population

Sørrig, R., Klausen, T. W., Salomo, M., Vangsted, A. J., Frølund, U. C., Andersen, K. T., Klostergaard, A., Helleberg, C., Pedersen, R. S., Pedersen, P. T., Helm-Petersen, S., Teodorescu, E. M., Preiss, B., Abildgaard, N., Gimsing, P., Danish Myeloma Study Group, Svirskaite, A., Teodorescu, E. M., Johnsen, H. E., Gregersen, H. & 2 others, Gade, I. L. & Bødker, J. S., 2017, In : PLOS ONE. 12, 12, 15 p., e0188988.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
10 Citations (Scopus)

Interactions between SNPs affecting inflammatory response genes are associated with multiple myeloma disease risk and survival

Nielsen, K. R., Rodrigo-Domingo, M., Steffensen, R., Baech, J., Bergkvist, K. S., Oosterhof, L., Schmitz, A., Bødker, J. S., Johansen, P., Vogel, U., Vangsted, A., Dybkær, K., Bøgsted, M. & Johnsen, H. E., 2017, In : Leukemia and Lymphoma. 58, 11, p. 2695-2704 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

5 Citations (Scopus)

Molecular Characteristics of High-Dose Melphalan Associated Oral Mucositis in Patients with Multiple Myeloma: A Gene Expression Study on Human Mucosa

Marcussen, M., Bødker, J. S., Christensen, H. S., Johansen, P., Nielsen, S., Christiansen, I., Bergmann, O. J., Bøgsted, M., Dybkær, K., Vyberg, M. & Johnsen, H. E., 2017, In : P L o S One. 12, 1, 18 p., e0169286.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
5 Citations (Scopus)

Molecular classification of tissue from a transformed non-Hogkin's lymphoma case with unexpected long-time remission

Bødker, J. S., Severinsen, M. T., El-Galaly, T. C., Brøndum, R. F., Laursen, M. B., Larsen, S. F., Nyegaard, M., Schmitz, A., Jakobsen, L. H., Schönherz, A. A., Due, H., Reinholdt, L., Bøgsted, M., Dybkær, K. & Johnsen, H. E., 2017, In : Experimental Hematology & Oncology. 6, 3.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
1 Citation (Scopus)
2016

Characterization of Memory B-Cells from Thymus and its Impact for DLBCL Classification

Bergkvist, K. S., Nørgaard, M. A., Bøgsted, M., Schmitz, A., Nyegaard, M., Gaihede, M., Bæch, J., Grønholdt, M-L., Jensen, F. S., Johansen, P., Urup, T., El-Galaly, T., Madsen, J., Bødker, J. S., Dybkær, K. & Johnsen, H. E., 2016, In : Experimental Hematology. 44, 10, p. 982-990.e11 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

3 Citations (Scopus)

hemaClass.org: Online One-By-One Microarray Normalization and Classification of Hematological Cancers for Precision Medicine

Larsen, S. F., Ellern Bilgrau, A., Brøndum, R. F., Hjort Jakobsen, L., Have, J., Lindblad Nielsen, K., El-Galaly, T. C., Bødker, J. S., Schmitz, A., H Young, K., Johnsen, H. E., Dybkær, K. & Bøgsted, M., 2016, In : P L o S One. 11, 10, 20 p., e0163711.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
6 Citations (Scopus)

High miR-34a expression improves response to doxorubicin in diffuse large B-cell lymphoma

Marques, S. C., Ranjbar, B., Laursen, M. B., Larsen, S. F., Bilgrau, A. E., Bødker, J. S., Jørgensen, L. T. K., Primo, M. N., Schmitz, A., Ettrup, M. S., Johnsen, H. E., Bøgsted, M., Mikkelsen, J. G. & Dybkær, K., 2016, In : Experimental Hematology. 44, 4, p. 238-246.e2 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

27 Citations (Scopus)

The CXCR4 antagonist plerixafor enhances the effect of rituximab in diffuse large B-cell lymphoma cell lines

Reinholdt, L., Laursen, M. B., Schmitz, A., Bødker, J. S., Jakobsen, L. H., Bøgsted, M., Johnsen, H. E. & Dybkær, K., 2016, In : Biomarker Research. 4, 12 p., 12.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
22 Citations (Scopus)

Unaccounted uncertainty from qPCR efficiency estimates entails uncontrolled false positive rates

Bilgrau, A. E., Larsen, S. F., Petersen, A., Kjeldsen, M. K., Bødker, J. S., Johnsen, H. E., Dybkær, K. & Bøgsted, M., 2016, In : BMC Bioinformatics. 17, 1, 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
1 Citation (Scopus)
185 Downloads (Pure)
2015

Diffuse Large B-Cell Lymphoma Classification System That Associates Normal B-Cell Subset Phenotypes With Prognosis

Dybkær, K., Bøgsted, M., Larsen, S. F., Bødker, J. S., Kjeldsen, M. K., Schmitz, A., Bilgrau, A. E., Xu-Monette, Z. Y., Li, L., Bergkvist, K. S., Laursen, M. B., Rodrigo, M., Marques, S. C., Rasmussen, S. B., Nyegaard, M., Gaihede, M., Møller, M. B., Samworth, R. J., Shah, R. D., Johansen, P. & 3 others, El-Galaly, T. C., Young, K. H. & Johnsen, H. E., 23 Mar 2015, In : Journal of Clinical Oncology. 33, 12, p. 1379-1388

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
53 Citations (Scopus)

Inherited Inflammatory Response Genes Are Associated with B-Cell Non-Hodgkin's Lymphoma Risk and Survival

Nielsen, K. R., Steffensen, R., Bendtsen, M. D., Rodrigo, M., Baech, J., Haunstrup, T. M., Bergkvist, K. S., Schmitz, A., Boedker, J. S., Johansen, P., Dybkær, K., Bøgsted, M. & Johnsen, H. E., 2015, In : PLOS ONE. 10, 10, 18 p., e0139329.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
5 Citations (Scopus)

Inherited variation in immune response genes in follicular lymphoma and diffuse large B-cell lymphoma

Nielsen, K. R., Steffensen, R., Haunstrup, T. M., Bødker, J. S., Dybkær, K., Baech, J., Bøgsted, M. & Johnsen, H. E., 2015, In : Leukemia and Lymphoma. 56, 12, p. 3257-3266 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

2 Citations (Scopus)

Long Noncoding RNA Expression during Human B-Cell Development

Petri, A., Dybkær, K., Bøgsted, M., Thrue, C. A., Hagedorn, P. H., Schmitz, A., Bødker, J. S., Johnsen, H. E. & Kauppinen, S., 2015, In : PLOS ONE. 10, 9, 19 p., e0138236.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
29 Citations (Scopus)

MicroRNAs in B-cells: from normal differentiation to treatment of malignancies

Marques, S. C., Laursen, M. B., Bødker, J. S., Kjeldsen, M. K., Larsen, S. F., Schmitz, A., Bøgsted, M., Johnsen, H. E. & Dybkær, K., 1 Jan 2015, In : OncoTarget. 6, 1, p. 7-25 19 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
18 Citations (Scopus)

Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models

Larsen, S. F., Dybkær, K., Young, K. H., Xu-Monette, Z. Y., El-Galaly, T. C., Laursen, M. B., Bødker, J. S., Kjeldsen, M. K., Schmitz, A., Nyegaard, M., Johnsen, H. E. & Bøgsted, M., 2015, In : B M C Cancer. 15, 1, 15 p., 235.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
26 Citations (Scopus)

Stable Phenotype Of B-Cell Subsets Following Cryopreservation and Thawing of Normal Human Lymphocytes Stored in a Tissue Biobank

Rasmussen, S. M., Bilgrau, A. E., Schmitz, A., Larsen, S. F., Bergkvist, K. S., Tramm, A. M., Baech, J., Jacobsen, C. L., Gaihede, M., Kjeldsen, M. K., Bødker, J. S., Dybkær, K., Bøgsted, M. & Johnsen, H. E., 2015, In : Cytometry. Part B: Clinical Cytometry. 88, 1, p. 40-49 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
20 Citations (Scopus)
2014

Exposure time independent summary statistics for assessment of drug dependent cell line growth inhibition

Larsen, S. F., Laursen, M. B., Bødker, J. S., Kjeldsen, M. K., Schmitz, A., Nyegaard, M., Johnsen, H. E., Dybkær, K. & Bøgsted, M., 2014, In : B M C Bioinformatics. 15, 168.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
14 Citations (Scopus)

Human B-cell cancer cell lines as a preclinical model for studies of drug effect in diffuse large B-cell lymphoma and multiple myeloma

Laursen, M. B., Larsen, S. F., Bødker, J. S., Schmitz, A., Kjeldsen, M. K., Sørensen, S., Madsen, J., El-Galaly, T. C., Bøgsted, M., Dybkær, K., Johnsen, H. E. & Myeloma Stem Cell Network (MSCNET), 26 Jul 2014, In : Experimental Hematology. 42, 11, p. 927-938 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

12 Citations (Scopus)

Reproducible probe-level analysis of the Affymetrix Exon 1.0 ST array with R/ Bioconductor

Rodrigo, M., Waagepetersen, R., Bødker, J. S., Larsen, S. F., Kjeldsen, M. K., Johnsen, H. E., Dybkær, K. & Bøgsted, M., 2014, In : Briefings in Bioinformatics. 15, 4, p. 519-533 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
7 Citations (Scopus)

SOX11 as a minimal residual disease marker for Mantle cell lymphoma

Simonsen, A. T., Sørensen, C. D., Ebbesen, L. H., Bødker, J. S., Bentzen, H. H. N. & Nyvold, C. G., 28 Apr 2014, In : Leukemia Research. 38, 8, p. 918-924

Research output: Contribution to journalJournal articleResearchpeer-review

10 Citations (Scopus)

Validation and implementation of a method for microarray gene expression profiling of minor B-cell subpopulations in man

Bergkvist, K. S., Nyegaard, M., Bøgsted, M., Schmitz, A., Bødker, J. S., Rasmussen, S. M., Perez-Andres, M., Larsen, S. F., Bilgrau, A. E., Kjeldsen, M. K., Gaihede, M., Nørgaard, M. A., Bæch, J., Grønholdt, M-L., Jensen, F. S., Johansen, P., Dybkær, K. & Johnsen, H. E., 31 Jan 2014, In : B M C Immunology. 15, 1, p. 3

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
9 Citations (Scopus)
2013

Performance Comparison of Affymetrix SNP6.0 and Cytogenetic 2.7M Whole-Genome Microarrays in Complex Cancer Samples

Bødker, J. S., Nielsen, C. G., Johansen, P., Schmitz, A., Madsen, J., Johnsen, H. E., Bøgsted, M., Dybkær, K. & Nyegaard, M., 2013, In : Cytogenetic and Genome Research. 139, 2, p. 80-87 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

5 Citations (Scopus)

Proof of the concept to use a malignant B cell line drug screen strategy for identification and weight of melphalan resistance genes in multiple myeloma

Bøgsted, M., Bilgrau, A. E., Wardell, C. P., Bertsch, U., Schmitz, A., Bødker, J. S., Kjeldsen, M. K., Goldschmidt, H., Morgan, G. J., Dybkær, K. & Johnsen, H. E., 20 Dec 2013, In : P L o S One. 8, 12, e83252.

Research output: Contribution to journalJournal articleResearchpeer-review

10 Citations (Scopus)
2012

A model system for assessing and comparing the ability of exon microarray and tag sequencing to detect genes specific for malignant B-cells

Kloster, M. B., Bilgrau, A. E., Rodrigo, M., Bergkvist, K. S., Schmitz, A., Sønderkær, M., Bødker, J. S., Larsen, S. F., Nyegaard, M., Johnsen, H. E., Nielsen, K. L., Dybkær, K. & Bøgsted, M., 2012, In : B M C Genomics. 13, 596, p. 1-13 596.

Research output: Contribution to journalJournal articleResearchpeer-review

1 Citation (Scopus)
2011

Increased expression of Transcription Factor TFAP2α correlates with chemosensitivity in advanced bladder cancer

Nordentoft, I. K., Andersen, L. D., Bødker, J. S., Wild, P., Hartmann, A., Bertz, S., Lehmann, J., Ørntoft, T. F. & Birkenkamp-Demtröder, K., 2011, In : B M C Cancer.

Research output: Contribution to journalJournal articleResearchpeer-review

24 Citations (Scopus)
2005

Additivity in effects of vitronectin and monoclonal antibodies against a-helix F of plasminogen activator inhibitor-1 on its reaction with target proteinases

Komissarov, A. A., Andreasen, P., Bødker, J. S., Declerck, P. J., Anagli, J. Y. & Shore, J. D., 2005, In : Journal of Biological Chemistry. 280, p. 1482-1489

Research output: Contribution to journalJournal articleResearchpeer-review

21 Citations (Scopus)
2004

Construction of a plasminogen activator inhibitor-1 variant without measurable affinity to vitronection buth otherwise normal

Jensen, J. K., Durand, M. K. V., Skeldal, S., Dupont, D. M., Bødker, J. S., Wind, T. & Andreasen, P., 2004, In : FEBS Letters. 556, p. 175-179 5 p.

Research output: Contribution to journalJournal articleResearchpeer-review

26 Citations (Scopus)

Plasminogen activator inhibitor-1 and tumour growth, invasion, and metastasis

Durand, M. K. V., Bødker, J. S., Christensen, A., Dupont, D. M., Hansen, M., Jensen, J. K., Kjelgaard, S., Mathiasen, L., Pedersen, K. E., Skeldal, S., Wind, T. & Andreasen, P. A., 2004, In : Thromb. Haemostas.. 91, p. 438-449 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

134 Citations (Scopus)
2003

Biochemical mechanism of action of a diketopiperazine inactivator of plasminogen activator inhibitor-1.

Einholm, A. P., Pedersen, K. E., Wind, T., Kulig, P., Overgaard, M. T., Jensen, J. K., Bødker, J. S., Christensen, A., Charlton, P. & Andreasen, P. A., 2003, In : Biochemical Journal. 373, Pt 3, p. 723-732 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

40 Citations (Scopus)

Mapping of the epitope for a monoclonal anti-plasminogen activator inhibitor-1 antibody protecting against inactivating agents

Bødker, J. S., Wind, T., Jensen, J. K., Hansen, M., Pedersen, K. E. & Andreasen, P. A., 2003, In : The FEBS Journal. 270, p. 1672-1679 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review