Research output per year
Research output per year
Research output
- 24 results
Search results
-
2024
Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca2+ coordinating residues.
Holler, C. V., Petersson, N. M., Brohus, M., Niemelä, M. A., Iversen, E. D., Overgaard, M. T., Iwaï, H. & Wimmer, R., Jan 2024, In: Cell Calcium. 117, p. 102831 1 p., 102831.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
2023
Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain
Brohus, M., Busuioc, A-O., Wimmer, R., Nyegaard, M. & Overgaard, M. T., 16 Aug 2023, In: Frontiers in Pharmacology. 14, 1210140.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)38 Downloads (Pure) -
Human calmodulin mutations cause arrhythmia and affect neuronal function in C. elegans
Jensen, H. H., Frantzen, M. T., Wesseltoft, J. L., Busuioc, A-O., Møller, K. V., Brohus, M., Duun, P. R., Nyegaard, M., Overgaard, M. T. & Olsen, A., 15 Jun 2023, In: Human Molecular Genetics. 32, 12, p. 2068-2083 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Citations (Scopus)68 Downloads (Pure) -
Hypothyroidism in hibernating brown bears
Frøbert, A. M., Nielsen, C. G., Brohus, M., Kindberg, J., Fröbert, O. & Overgaard, M. T., 1 Feb 2023, In: Thyroid research. 16, 1, 3.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)44 Downloads (Pure) -
2022
Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin
Frøbert, A. M., Brohus, M., Toews, J. N. C., Round, P., Fröbert, O., Hammond, G. L. & Overgaard, M. T., Feb 2022, In: FEBS open bio. 12, 2, p. 362-378 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)77 Downloads (Pure) -
Circulating insulin-like growth factor system adaptations in hibernating brown bears indicate increased tissue IGF availability
Frøbert, A. M., Brohus, M., Roesen, T. S., Kindberg, J., Fröbert, O., Conover, C. A. & Overgaard, M. T., 1 Sept 2022, In: American Journal of Physiology: Endocrinology and Metabolism. 323, 3, p. E307-E318Research output: Contribution to journal › Journal article › Research › peer-review
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Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats
Frøbert, A. M., Toews, J. N. C., Nielsen, C. G., Brohus, M., Kindberg, J., Jessen, N., Fröbert, O., Hammond, G. L. & Overgaard, M. T., 1 Sept 2022, In: Physiological and Biochemical Zoology. 95, 5, p. 365-378 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
1 Citation (Scopus) -
Exploring Approaches for Blended Learning in Life Sciences
Brohus, M., Rohde, P. D., Gregersen Echers, S., Westphal, K., Ern, R. & Jensen, H. H., 24 Nov 2022, In: Journal of Problem Based Learning in Higher Education. 10, 1, p. 88-100 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access -
Plasma proteomics data from hibernating and active Scandinavian brown bears
Frøbert Harbo, A. M., Gregersen Echers, S., Brohus, M., Welinder, K. G., Kindberg, J., Fröbert, O. & Overgaard, M. T., Apr 2022, In: Data in Brief. 41, 107959.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile1 Citation (Scopus)35 Downloads (Pure) -
2021
Infanticide vs. inherited cardiac arrhythmias
Brohus, M., Arsov, T., Wallace, D. A., Jensen, H. H., Nyegaard, M., Crotti, L., Adamski, M., Zhang, Y., Field, M. A., Athanasopoulos, V., Baró, I., Ribeiro de Oliveira-Mendes, B. B., Redon, R., Charpentier, F., Raju, H., DiSilvestre, D., Wei, J., Wang, R., Rafehi, H., Kaspi, A., & 7 others, Mar 2021, In: Europace. 23, 3, p. 441-450 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile20 Citations (Scopus)42 Downloads (Pure) -
The first junior European Calcium Society meeting: calcium research across scales, Kingdoms and countries
Diercks, B-P., Jensen, H. H., Chalmers, S. B., Coode, E., Vaughan, M. B., Tadayon, R., Sáez, P. J., Davis, F. M. & Brohus, M. B., 2021, In: BBA Molecular Cell Research. 1868, 6, 118999.Research output: Contribution to journal › Conference article in Journal › Research › peer-review
1 Citation (Scopus) -
University Pedagogy Report: Exploring approaches for blended learning
Jensen, H. H., Westphal, K. R., Brohus, M. B., Rohde, P. D., Andersen, R. E. & Gregersen Echers, S., 2021Research output: Other contribution › Education
Open AccessFile110 Downloads (Pure) -
2020
Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+ binding and cause misfolding
Wang, K., Brohus, M., Holt, C., Overgaard, M. T., Wimmer, R. & Van Petegem, F., Mar 2020, In: The Journal of Physiology. 598, 6, p. 1169-1186 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile22 Citations (Scopus)55 Downloads (Pure) -
Role of cardiac ryanodine receptor calmodulin-binding domains in mediating the action of arrhythmogenic calmodulin N-domain mutation N54I
Søndergaard, M. T., Liu, Y., Guo, W., Wei, J., Wang, R., Brohus, M., Overgaard, M. T. & Chen, S. R. W., Jun 2020, In: The FEBS Journal. 287, 11, p. 2256-2280 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)61 Downloads (Pure) -
The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor
Holt, C., Hamborg, L., Lau, K., Brohus, M., Sørensen, A. B., Larsen, K. T., Sommer, C., Van Petegem, F., Overgaard, M. T. & Wimmer, R., 29 May 2020, In: Journal of Biological Chemistry. 295, 22, p. 7620-7634 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
20 Citations (Scopus) -
2019
A novel mutation in calmodulin causes dysregulation of calcium channels
Jensen, H. H., Brohus, M. B., Dick, I. E., Søndergaard, M. T., Liu, Y., Chen, W. S. R., Nyegaard, M., Kjærulf Jensen, H. & Overgaard, M. T., 18 Sept 2019.Research output: Contribution to conference without publisher/journal › Poster › Research
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Ca2+ dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains
Brohus, M., Søndergaard, M. T., Chen, W. S. R., Van Petegem, F. & Overgaard, M. T., 18 Jan 2019, In: Biochemical Journal. 476, 2, p. 193-209 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile22 Citations (Scopus)228 Downloads (Pure) -
Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations
Søndergaard, M. T., Liu, Y., Brohus, M., Guo, W., Nani, A., Carvajal, C., Fill, M., Overgaard, M. T. & Chen, S. R. W., Nov 2019, In: F E B S Journal. 286, 22, p. 4554-4578 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile17 Citations (Scopus)74 Downloads (Pure) -
2018
Arrhythmia mutations in calmodulin cause conformational changes that affect interactions with the cardiac voltage-gated calcium channel
Wang, K., Holt, C., Lu, J., Brohus, M., Larsen, K. T., Overgaard, M. T., Wimmer, R. & Van Petegem, F., 6 Nov 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10556-E10565 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access30 Citations (Scopus) -
Human calmodulin mutations
Jensen, H. H., Brohus, M., Nyegaard, M. & Overgaard, M. T., 13 Nov 2018, In: Frontiers in Molecular Neuroscience. 11, 9 p., 396.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile75 Citations (Scopus)229 Downloads (Pure) -
The Arrhythmogenic Calmodulin interactome: elucidation of molecular mechanisms
Brohus, M., 2018Research output: PhD thesis
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2016
Abnormal IGF-Binding Protein Profile in the Bone Marrow of Multiple Myeloma Patients
Bieghs, L., Brohus, M., Kristensen, I. B., Abildgaard, N., Bøgsted, M., Johnsen, H. E., Conover, C. A., De Bruyne, E., Vanderkerken, K., Overgaard, M. T. & Nyegaard, M., 2016, In: PLOS ONE. 11, 4, 10 p., e0154256.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile8 Citations (Scopus)279 Downloads (Pure) -
Biochemical Foundations of Health and Energy Conservation in Hibernating Free-Ranging Subadult Brown Bear Ursus arctos
Welinder, K. G., Hansen, R., Overgaard, M. T., Brohus, M., Sønderkær, M., von Bergen, M., Rolle-Kampczyk, U., Otto, W., Lindahl, T. L., Arinell, K., Evans, A. L., Swenson, J. E., Revsbech, I. G. & Frobert, O., 21 Oct 2016, In: Journal of Biological Chemistry. 291, 43, p. 22509-22523 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access31 Citations (Scopus) -
2015
The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat
Brohus, M., Gorbunova, V., Faulkes, C. G., Overgaard, M. T. & Conover, C. A., 2015, In: PLOS ONE. 10, 12, p. 1-17 e0145587.Research output: Contribution to journal › Journal article › Research › peer-review
Open Access15 Citations (Scopus)