Projects per year
Personal profile
Research profile
The aim of my research is to study brain diseases and identify how brain diseases develop and progress. Based on this research I want to develop treatment strategies to help patients suffering from diseases like Multiple Sclerosis, Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease Huntington's disease and others. Give these patients a possibility to treat themselves through diet, food additives, vitamins, and also to develop new classes of medicine. We have come a long way as we published and are publishing, but there is still a way to go.
Keywords
- Medicine
- Biomedicine
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Collaborations from the last five years
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Projects
- 1 Active
Research output
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Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS
Trabjerg, M. S., Andersen, D. C., Huntjens, P., Oklinski, K. E., Bolther, L., Hald, J. L., Baisgaard, A. E., Mørk, K., Warming, N., Kullab, U. B., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J. & Nieland, J. D. V., 30 Apr 2021, In: Communications Biology. 4, 1, 509.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile12 Citations (Scopus)68 Downloads (Pure) -
Dysregulation of metabolic pathways by carnitine palmitoyl-transferase 1 plays a key role in central nervous system disorders: experimental evidence based on animal models
Trabjerg, M. S., Mørkholt, A. S., Lichota, J., Oklinski, M. K. E., Andersen, D. C., Jønsson, K., Mørk, K., Skjønnemand, M-L. N., Kroese, L. J., Pritchard, C. E. J., Huijbers, I. J., Gazerani, P., Corthals, A. & Nieland, J. D. V., 24 Sept 2020, In: Scientific Reports. 10, 1, 15583.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile9 Citations (Scopus)86 Downloads (Pure) -
Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism
Mørkholt, A. S., Wiborg, O., Nieland, J. G. K., Nielsen, S. & Nieland, J. D., 19 May 2017, In: Scientific Reports. 7, 9 p., 2158.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile19 Citations (Scopus)345 Downloads (Pure) -
Identification of brain antigens recognized by autoantibodies in experimental autoimmune encephalomyelitis-induced animals treated with etomoxir or interferon-β
Mørkholt, A. S., Kastaniegaard, K., Trabjerg, M. S., Gopalasingam, G., Niganze, W., Larsen, A., Stensballe, A., Nielsen, S. & Nieland, J. D., 4 May 2018, In: Scientific Reports. 8, 1, 11 p., 7092.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile10 Citations (Scopus)319 Downloads (Pure) -
Antigen presentation by B cells enables epitope spreading across an MHC barrier
Fahlquist-Hagert, C., Wittenborn, T. R., Terczyńska-Dyla, E., Kastberg, K. S., Yang, E., Rallistan, A. N., Markett, Q. R., Winther, G., Fonager, S., Voss, L. F., Pedersen, M. K., van Campen, N., Ferapontov, A., Jensen, L., Huang, J., Nieland, J. D., van der Poel, C. E., Palmfeldt, J., Carroll, M. C., Utz, P. J., & 3 others, 31 Oct 2023, In: Nature Communications. 14, 1, 6941.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile2 Downloads (Pure)
Datasets
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Histological and MRI brain atlas of the common shrew, Sorex araneus, with brain region-specific gene expression profiles
Baldoni, C. (Creator), Thomas, W. (Creator), Von Elverfeldt, D. (Creator), Reisert, M. (Creator), Làzaro, J. (Creator), Muturi, M. (Creator), Dàvalos, L. (Creator) & Nieland, J. D. (Creator), Edmond, 16 Feb 2023
DOI: 10.17617/3.hvw8zn, https://edmond.mpdl.mpg.de/citation?persistentId=doi:10.17617/3.HVW8ZN
Dataset
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16s rRNA sequencing data for Downregulating carnitine palmitoyl transferase 1 strongly affects disease progression in the SOD1 G93A mouse model
Andersen, D. (Contributor), Baisgaard, A. E. (Contributor), Bolther, L. (Contributor), Hald, J. (Contributor), Huijbers, I. (Contributor), Huntjens, P. (Contributor), Kroese, L. (Contributor), Kullab, U. (Contributor), Mørk, K. (Contributor), Nieland, J. D. (Contributor), Oklinski, K. (Contributor), Pritchard, C. (Contributor), Trabjerg, M. (Creator) & Warming, N. (Contributor), Mendeley Data, 12 Mar 2021
DOI: 10.17632/6zt29bjbzd.1, https://data.mendeley.com/datasets/6zt29bjbzd
Dataset: Supplementary material
Activities
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Founder and CSO
John Dirk Nieland (Consultant)
1 Aug 2019 → …Activity: Public/private sector consultancy and other employment › Employment with any other public or private company including your own company
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European Directorate of the Quality of Medicine EDQM (External organisation)
John Dirk Nieland (Chairperson)
1 Mar 2019 → 1 Dec 2021Activity: Memberships › Membership of committees, commissions, boards, councils, associations, organisations, or similar
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Founder and CSO
John Dirk Nieland (Consultant)
1 Dec 2016 → …Activity: Public/private sector consultancy and other employment › Employment with any other public or private company including your own company
Press/Media
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Meet the mammals that eat their own brains
30/11/2022
1 item of Media coverage
Press/Media: Press / Media
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2N Pharma får millionstøtte af det amerikanske forsvarsministerium til at finde kur mod ALS
12/04/2022
1 item of Media coverage
Press/Media: Press / Media
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Forsker udtaler sig om hudsygdommen vitiligio
28/03/2017
1 item of Media coverage
Press/Media: Press / Media